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Investigating the effects of different settings of deep brain stimulation on gait using mobile sensors

Description

People with Parkinson's disease often report problems with walking. In addition to pathognomonic phenomena such as freezing of gait (FoG), gait is often slower and steps are smaller. Current methods of adjusting deep brain stimulation (DBS) often neglect this aspect of the disease.

This study investigates the effects of different DBS settings on gait. The frequency, stimulation intensity and pulse duration of the stimulation are systematically changed. Meanwhile, the gait pattern will be recorded using portable sensors that may in the future be used at home. We hope that this study will help us to find out which DBS settings have a positive effect on walking.

Publications

Mügge, F., Kleinholdermann, U., Heun, A., Ollenschläger, M., Hannink, J., & Pedrosa, D. J. (2023). Subthalamic 85 Hz deep brain stimulation improves walking pace and stride length in Parkinson’s disease patients. Neurological Research and Practice, 5(1), 1-11. https://doi.org/10.1186/s42466-023-00263-7

Contact

Herr Dr. rer nat. Urs Kleinholdermann,
Frau Amelie Heun
Telefon: 06421/58 - 65299
Telefax: 06421/58 - 67055
kleinhol@staff.*

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