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Anatomical predictors for the postoperative outcome after deep brain stimulation based on microstructure in Parkinson's disease (predictDBS)

Description

Deep brain stimulation (DBS) in the area of the subthalamic nucleus (STN) is an established therapy for treating the core motor symptoms of Parkinson's disease. However, its effects on so-called axial symptoms such as freezing of gait (FOG) and on cognitive performance are less well understood. The aim of this retrospective study is to identify microstructural properties associated with the individual response to STN-THS in Parkinson's patients. In the long term, the results should contribute to the development of predictive markers that enable more precise patient selection, individualised programming of stimulation parameters and better clarification of possible therapy expectations.

Contact

Dr. med. Alexander Calvano
Dr. med. Philipp Löhrer, Prof. Dr. Miriam Bopp, Inga Zeilfelder
Telefone: 06421/58 - 65299
Telefax: 06421/58 - 67055
Mail: alexander.calvano@staff.*

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