Main Content
Publication list of the institute from 2019
Badr M & K Jöhrens & M Allgäuer & M Boxberg & W Weichert & I Tinhofer & C Denkert & P Schirmacher & A Stenzinger & J Budczies (2019)
Morphomolecular analysis of the immune tumor microenvironment in human head and neck cancer
in: Cancer immunology, immunotherapy (68)
10.1007/s00262-019-02378-w
Barupal D K & B Gao & J Budczies & B S Phinney & B Perroud & C Denkert & O Fiehn (2019)
Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining
in: Oncotarget (10)
10.18632/oncotarget.26995
Basudan A & N Priedigkeit & R J Hartmaier & E S Sokol & A Bahreini & R J Watters & M M Boisen & R Bhargava & K R Weiss & M M Karsten & C Denkert & J-U Blohmer & J P Leone & R L Hamilton & A M Brufsky & E Elishaev & P C Lucas & A V Lee & S Oesterreich (2019)
Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer
in: Molecular cancer research (17)
10.1158/1541-7786.MCR-18-0946
Budau L & C Wilhelm & R Moll & J Jäkel & C Hirt & G Dölken & G Maschmeyer & E Neubauer & K Strauch & A Burchert & M Herold & A Neubauer (2019)
Low number of intrafollicular T cells may predict favourable response to rituximab-based immuno-chemotherapy in advanced follicular lymphoma: a secondary analysis of a randomized clinical trial
in: Journal of Cancer Research and Clinical Oncology (145)
10.1007/s00432-019-02961-9
Burstein H J & G Curigliano & S Loibl & P Dubsky & M Gnant & P Poortmans & M Colleoni & C Denkert & M Piccart-Gebhart & M Regan & H-J Senn & E P Winer & B Thurlimann & Members of the St. Gallen International Consensus Panel on the Primary Therapy of Early Breast Cancer 2019 (2019)
Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019
in: Annals of Oncology (30)
10.1093/annonc/mdz235
Denkert C & J Budczies & M M Regan & S Loibl & P Dell'Orto & G von Minckwitz & M G Mastropasqua & C Solbach & B Thürlimann & K Mehta & J-U Blohmer & M Colleoni & V Müller & F Klauschen & B Ataseven & K Engels & R Kammler & B M Pfitzner & M Dietel & P A Fasching & G Viale (2019)
Clinical and analytical validation of Ki-67 in 9069 patients from IBCSG VIII + IX, BIG1-98 and GeparTrio trial: systematic modulation of interobserver variance in a comprehensive in silico ring trial
in: Breast Cancer Research and Treatment (176)
10.1007/s10549-018-05112-9
Guan J & S Darb-Esfahani & R Richter & E T Taube & I Ruscito & S Mahner & L Woelber & K Prieske & N Concin & I Vergote & E Van Nieuwenhuysen & P Achimas-Cadariu & J Glajzer & H Woopen & M Stanske & H Kulbe & C Denkert & J Sehouli & E I Braicu (2019)
Vascular endothelial growth factor receptor 2 (VEGFR2) correlates with long-term survival in patients with advanced high-grade serous ovarian cancer (HGSOC): a study from the Tumor Bank Ovarian Cancer (TOC) Consortium
in: Journal of Cancer Research and Clinical Oncology (145)
10.1007/s00432-019-02877-4
Heitz F & S Kümmel & B Lederer & C Solbach & K Engels & B Ataseven & B Sinn & J U Blohmer & C Denkert & J Barinoff & A Fisseler-Eckhoff & S Loibl (2019)
Impact of Nuclear Oestrogen Receptor Beta Expression in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
in: Geburtshilfe Und Frauenheilkunde (79)
10.1055/a-0987-9898
Janning M & V Müller & E Vettorazzi & M Cubas-Cordova & V Gensch & I Ben-Batalla & C Zu Eulenburg & C Schem & P A Fasching & B Schnappauf & T Karn & T Fehm & M Just & T Kühn & F Holms & F Overkamp & P Krabisch & B Rack & C Denkert & M Untch & H Tesch & M Rezai & K Kittel & K Pantel & C Bokemeyer & S Loibl & G von Minckwitz & S Loges (2019)
Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial
in: International Journal of Cancer (145)
10.1002/ijc.32163
Jurmeister P & A Schöler & A Arnold & F Klauschen & D Lenze & M Hummel & L Schweizer & H Bläker & B M Pfitzner & S Mamlouk & C Sers & C Denkert & D Stichel & N Frost & D Horst & M von Laffert & D Capper (2019)
DNA methylation profiling reliably distinguishes pulmonary enteric adenocarcinoma from metastatic colorectal cancer
in: Modern Pathology (32)
10.1038/s41379-019-0207-y
Klein O & F Kanter & H Kulbe & P Jank & C Denkert & G Nebrich & W D Schmitt & Z Wu & C A Kunze & J Sehouli & S Darb-Esfahani & I Braicu & J Lellmann & H Thiele & E T Taube (2019)
MALDI-Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods
in: Proteomics. Clinical Applications (13)
10.1002/prca.201700181
Krug D & B Lederer & F Seither & V Nekljudova & B Ataseven & J-U Blohmer & S D Costa & C Denkert & N Ditsch & B Gerber & C Hanusch & J Heil & J Hilfrich & J B Huober & C Jackisch & S Kümmel & S Paepke & C Schem & A Schneeweiss & M Untch & J Debus & G von Minckwitz & T Kühn & S Loibl (2019)
Post-Mastectomy Radiotherapy After Neoadjuvant Chemotherapy in Breast Cancer: A Pooled Retrospective Analysis of Three Prospective Randomized Trials
in: Annals of Surgical Oncology (26)
10.1245/s10434-019-07635-x
Kuemmel S & J Holtschmidt & B Gerber & A Von der Assen & J Heil & M Thill & D Krug & C Schem & C Denkert & J Lubitz & J U Blohmer & M Reinisch & M Hötzeldt & F Seither & V Nekljudova & I Schwidde & K Uhrhan & G Von Minckwitz & M Rezai & J Mulowski & S Loibl & T Kuehn (2019)
Prospective, Multicenter, Randomized Phase III Trial Evaluating the Impact of Lymphoscintigraphy as Part of Sentinel Node Biopsy in Early Breast Cancer: SenSzi (GBG80) Trial
in: Journal of Clinical Oncology (37)
10.1200/JCO.18.02092
Kugelmann D & V Rötzer & E Walter & D T Egu & M T Fuchs & F Vielmuth & H Vargas-Robles & M Schnoor & M Hertl & R Eming & K Rottner & A Schmidt & V Spindler & J Waschke (2019)
Role of Src and Cortactin in Pemphigus Skin Blistering
in: Frontiers in Immunology (10)
10.3389/fimmu.2019.00626
Laible M & K Hartmann & C Gürtler & T Anzeneder & R Wirtz & S Weber & T Keller & U Sahin & M Rees & A Ramaswamy (2019)
Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy
in: BMC cancer (19)
10.1186/s12885-019-5890-z
Lebeau A & C Denkert & P Sinn & M Schmidt & A Wöckel (2019)
[Update of the German S3 breast cancer guideline : What is new for pathologists?]
in: Der Pathologe (40)
10.1007/s00292-019-0578-3
Levine K M & N Priedigkeit & A Basudan & N Tasdemir & M J Sikora & E S Sokol & R J Hartmaier & K Ding & N Z Ahmad & R J Watters & K R Weiss & J-U Blohmer & C Denkert & A Machleidt & M M Karsten & M M Boisen & E Elishaev & P C Lucas & A V Lee & S Oesterreich (2019)
FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype
in: NPJ breast cancer (5)
10.1038/s41523-019-0114-x
Löffler M W & B Nussbaum & G Jäger & P S Jurmeister & J Budczies & P L Pereira & S Clasen & D J Kowalewski & L Mühlenbruch & I Königsrainer & S Beckert & R Ladurner & S Wagner & F Bullinger & T H Gross & C Schroeder & B Sipos & A Königsrainer & S Stevanović & C Denkert & H-G Rammensee & C Gouttefangeas & S P Haen (2019)
A Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer
in: Frontiers in Immunology (10)
10.3389/fimmu.2019.02526
Loi S & D Drubay & S Adams & G Pruneri & P A Francis & M Lacroix-Triki & H Joensuu & M V Dieci & S Badve & S Demaria & R Gray & E Munzone & J Lemonnier & C Sotiriou & M J Piccart & P-L Kellokumpu-Lehtinen & A Vingiani & K Gray & F Andre & C Denkert & R Salgado & S Michiels (2019)
Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers
in: Journal of Clinical Oncology (37)
10.1200/JCO.18.01010
Loibl S & D Treue & J Budczies & K Weber & A Stenzinger & W D Schmitt & W Weichert & P Jank & J Furlanetto & F Klauschen & T Karn & N Pfarr & G von Minckwitz & M Möbs & C Jackisch & C Sers & A Schneeweiss & P A Fasching & C Schem & M Hummel & M van Mackelenbergh & V Nekljudova & M Untch & C Denkert (2019)
Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial
in: Clinical Cancer Research (25)
10.1158/1078-0432.CCR-18-3258
Loibl S & M Untch & N Burchardi & J Huober & B V Sinn & J-U Blohmer & E-M Grischke & J Furlanetto & H Tesch & C Hanusch & K Engels & M Rezai & C Jackisch & W D Schmitt & G von Minckwitz & J Thomalla & S Kümmel & B Rautenberg & P A Fasching & K Weber & K Rhiem & C Denkert & A Schneeweiss (2019)
A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study
in: Annals of Oncology (30)
10.1093/annonc/mdz158
Noske A & V Möbus & K Weber & S Schmatloch & W Weichert & C-H Köhne & C Solbach & B Ingold Heppner & K Steiger & V Müller & P Fasching & T Karn & M van Mackelenbergh & F Marmé & W D Schmitt & C Schem & E Stickeler & S Loibl & C Denkert (2019)
Relevance of tumour-infiltrating lymphocytes, PD-1 and PD-L1 in patients with high-risk, nodal-metastasised breast cancer of the German Adjuvant Intergroup Node-positive study
in: European Journal of Cancer (114)
10.1016/j.ejca.2019.04.010
Rimm D L & S C Y Leung & L M McShane & Y Bai & A L Bane & J M S Bartlett & J Bayani & M C Chang & M Dean & C Denkert & E K Enwere & C Galderisi & A Gholap & J C Hugh & A Jadhav & E N Kornaga & A Laurinavicius & R Levenson & J Lima & K Miller & L Pantanowitz & T Piper & J Ruan & M Srinivasan & S Virk & Y Wu & H Yang & D F Hayes & T O Nielsen & M Dowsett (2019)
An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer
in: Modern Pathology (32)
10.1038/s41379-018-0109-4
Rüder U & C Denkert & C A Kunze & P Jank & J Lindner & K Jöhrens & H Kulbe & J Sehouli & M Dietel & E Braicu & S Darb-Esfahani (2019)
APOBEC3B protein expression and mRNA analyses in patients with high-grade serous ovarian carcinoma
in: Histology and Histopathology (34)
10.14670/HH-18-050
Schneeweiss A & C Denkert & P A Fasching & C Fremd & O Gluz & C Kolberg-Liedtke & S Loibl & H-J Lück (2019)
Diagnosis and Therapy of Triple-Negative Breast Cancer (TNBC) - Recommendations for Daily Routine Practice
in: Geburtshilfe Und Frauenheilkunde (79)
10.1055/a-0887-0285
Schneeweiss A & V Möbus & H Tesch & C Hanusch & C Denkert & K Lübbe & J Huober & P Klare & S Kümmel & M Untch & K Kast & C Jackisch & J Thomalla & B Ingold-Heppner & J-U Blohmer & M Rezai & M Frank & K Engels & K Rhiem & P A Fasching & V Nekljudova & G von Minckwitz & S Loibl (2019)
Intense dose-dense epirubicin, paclitaxel, cyclophosphamide versus weekly paclitaxel, liposomal doxorubicin (plus carboplatin in triple-negative breast cancer) for neoadjuvant treatment of high-risk early breast cancer (GeparOcto-GBG 84): A randomised phase III trial
in: European Journal of Cancer (106)
10.1016/j.ejca.2018.10.015
Schüttler K-F & A Götschenberg & A Klasan & T Stein & A Pehl & P P Roessler & J Figiel & T J Heyse & T Efe (2019)
Cell-free cartilage repair in large defects of the knee: increased failure rate 5 years after implantation of a collagen type I scaffold
in: Archives of Orthopaedic and Trauma Surgery (139)
10.1007/s00402-018-3028-4
Sehouli J & E I Braicu & R Richter & C Denkert & P Jank & P S Jurmeister & C A Kunze & J Budczies & S Darb-Esfahani & W D Schmitt & A Traut & J Grabowski & E T Taube & H Plett (2019)
Prognostic significance of Ki-67 levels and hormone receptor expression in low-grade serous ovarian carcinoma: an investigation of the Tumor Bank Ovarian Cancer Network
in: Human Pathology (85)
10.1016/j.humpath.2018.10.020
Sinn B V & K E Weber & W D Schmitt & P A Fasching & W F Symmans & J-U Blohmer & T Karn & E T Taube & F Klauschen & F Marmé & C Schem & E Stickeler & B Ataseven & J Huober & G von Minckwitz & B Seliger & C Denkert & S Loibl (2019)
Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy
in: Breast cancer research (21)
10.1186/s13058-019-1231-z
Solimani F & R Pollmann & T Schmidt & A Schmidt & X Zheng & R Savai & S Mühlenbein & J Pickert & V Eubel & C Möbs & R Eming & M Hertl (2019)
Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus
in: Frontiers in Immunology (10)
10.3389/fimmu.2019.01808
Solimani F & R Maglie & R Pollmann & T Schmidt & A Schmidt & N Ishii & B Tackenberg & A Kirschbaum & D Didona & J Pickert & R Eming & T Hashimoto & M Hertl (2019)
Thymoma-Associated Paraneoplastic Autoimmune Multiorgan Syndrome-From Pemphigus to Lichenoid Dermatitis
in: Frontiers in Immunology (10)
10.3389/fimmu.2019.01413
Tray N & J Taff & B Singh & J Suh & N Ngo & M Kwa & A B Troxel & Y K Chae & R Kurzrock & S P Patel & E Sharon & C Denkert & J S Ross & S Adams (2019)
Metaplastic breast cancers: Genomic profiling, mutational burden and tumor-infiltrating lymphocytes
in: Breast (44)
10.1016/j.breast.2018.12.010
Trenker C & M Dohse & A Ramaswamy & C Michel & C Görg (2019)
Histological validation of pulmonary infarction detected with contrast-enhanced ultrasound in patients with negative computed tomography pulmonary angiogram: A case series
in: Journal of clinical ultrasound (47)
10.1002/jcu.22755
Untch M & C Jackisch & A Schneeweiss & S Schmatloch & B Aktas & C Denkert & C Schem & H Wiebringhaus & S Kümmel & M Warm & P A Fasching & M Just & C Hanusch & J Hackmann & J-U Blohmer & K Rhiem & W D Schmitt & J Furlanetto & B Gerber & J Huober & V Nekljudova & G von Minckwitz & S Loibl (2019)
NAB-Paclitaxel Improves Disease-Free Survival in Early Breast Cancer: GBG 69-GeparSepto
in: Journal of Clinical Oncology (37)
10.1200/JCO.18.01842
Vercellino G F & E Erdemoglu & P Lichtenberg & M Z Muallem & R Richter & N R Abu-Rustum & M Plante & F Lécuru & S Greggi & B J Monk & S Sagae & C Denkert & M Keller & M Alhakeem & M Hellriegel & A M Dückelmann & V Chiantera & J Sehouli (2019)
A GCIG international survey: clinical practice patterns of sentinel lymph node biopsies in cervical cancer
in: Archives of Gynecology and Obstetrics (300)
10.1007/s00404-019-05164-2
Voglstaetter M & A R Thomsen & J Nouvel & A Koch & P Jank & E G Navarro & T Gainey-Schleicher & R Khanduri & A Groß & F Rossner & C Blaue & C M Franz & M Veil & G Puetz & A Hippe & J Dindorf & J Kashef & W Thiele & B Homey & C Greco & C Boucheix & A Baur & T Erbes & C F Waller & M Follo & G Hossein & C Sers & J Sleeman & I Nazarenko (2019)
Tspan8 is expressed in breast cancer and regulates E-cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles
in: The Journal of Pathology (248)
10.1002/path.5281
Wächter S & K Holzer & J Manoharan & C Brehm & I Mintziras & D K Bartsch & E Maurer (2019)
[Surgical treatment of parathyroid carcinoma : Does the initial en bloc resection improve the prognosis?]
in: Der Chirurg (90)
10.1007/s00104-019-1007-0
Wagner J & M A Rapsomaniki & S Chevrier & T Anzeneder & C Langwieder & A Dykgers & M Rees & A Ramaswamy & S Muenst & S D Soysal & A Jacobs & J Windhager & K Silina & M van den Broek & K J Dedes & M Rodríguez Martínez & W P Weber & B Bodenmiller (2019)
A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer
in: Cell (177)
10.1016/j.cell.2019.03.005
Wehrle A & T M Witkos & S Unger & J Schneider & J A Follit & J Hermann & T Welting & V Fano & M Hietala & N Vatanavicharn & K Schoner & J Spranger & M Schmidts & B Zabel & G J Pazour & A Bloch-Zupan & G Nishimura & A Superti-Furga & M Lowe & E Lausch (2019)
Hypomorphic mutations of TRIP11 cause odontochondrodysplasia
in: JCI insight (4)
10.1172/jci.insight.124701
Witzel I & S Loibl & R Wirtz & P A Fasching & C Denkert & K Weber & H-J Lück & J Huober & T Karn & M v Mackelenbergh & F Marmé & C Schem & E Stickeler & M Untch & V Müller (2019)
Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial
in: British Journal of Cancer (121)
10.1038/s41416-019-0630-3