Hauptinhalt

2022

Köck Z, Schnelle K, Persechino M, Umbach S, Schihada H, Januliene D, Parey K, Pockes S, Kolb P, Dötsch V, Möller A, Hilger D, Bernhard F (2024). Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment. Nat. Commun. 15: 1831.

Levin R, Köck Z, Martin J, Zangl R, Gewering T, Schüler L, Moeller A, Dötsch V, Morgner N, Bernhard F (2022). Cotranslational assembly of membrane protein/nanoparticles in cell-free systems. BBA 1864: 184018.

Persechino M, Hedderich JB, Kolb P, Hilger D (2022). Allosteric modulation of GPCRs: From structural insights to in silico drug discovery. Pharmacol. Ther. 237: 108242.

Köck Z, Ermel U, Martin J, Morgner N, Frangakis AS, Dötsch V, Hilger D, Bernhard F (2022). Biochemical characterization of cell-free synthesized human β₁-adrenergic receptor cotranslationally inserted into nanodiscs. J. Mol. Biol. 434: 167687.

Hedderich JB, Persechino M, Becker K, Heydenreich FM, Gutermuth T, Bouvier M, Bünemann M, Kolb P (2022). The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites. Nat. Commun. 13: 2567.

Umbach S, Levin R, Neumann S, Steinmetzer T, Dötsch V, Bernhard F (2022). Transfer mechanism of cell-free synthesized membrane proteins into mammalian cells. Front. Bioeng. Biotechnol. 10: 906295.

Glueck D, Grethen A, Das M, Mmeka OP, Pérez Patallo E, Meister A, Rajender R, Kins S, Räschle M, Victor J, Chu C, Etzkorn M, Köck Z, Bernhard F, Babalola JO, Vargas C, Keller S (2022). Electroneutral polymer nanodiscs enable interference-free probing of membrane proteins in a lipid-bilayer environment. Small 2022: 2202492.

Umbach S, Dötsch V, Bernhard F (2022). Cell-Free Expression of GPCRs into Nanomembranes for Functional and Structural Studies. Meth. Mol. Biol. 2507: 7.

Mezhyrova J, Mörs K, Glaubitz C, Dötsch V (2022). Applications of cell-free synthesized membrane protein precipitates. Meth. Mol. Biol. 2406: 245.

2021

Köck Z, Dötsch V, Bernhard F (2021). Screening methods for cell-free synthesised GPCR/nanoparticle samples. Meth. Mol. Biol. 2268: 97.

2020

Carvalho J, Chennupati R, Li R, Günther S, Kaur H, Zhao W, Tonack S, Kurz M, Mößlein N, Bünemann M, Offermanns S, Wettschureck N (2020). Orphan G-protein-coupled receptor GPRC5B controls smooth muscle contractility and differentiation by inhibiting prostacyclin receptor signaling. Circulation 141: 1168-83.

Levin R, Köck Z, Dötsch V, Bernhard F (2020). Co-translational Insertion of Membrane Proteins into Preformed Nanodiscs. J. Vis. Exp. 165: e61844.

Krug U, Gloge A, Schmidt P, Baldus J, Bernhard F, Kaiser A, Montag C, Gauglitz M, Vishnivetskiy SA, Gurevich VV, Beck-Sickinger AG, Glaubitz C, Huster D (2020). The Conformational Equilibrium of the Neuropeptide Y2 Receptor. Angew. Chem. Int. Ed. 59: 2