Hauptinhalt
Publications
de Vries S, Fürst-Jansen JMR, Irisarri I, Dhabalia Ashok A, Ischebeck T, Feussner K, Abreu IN, Petersen M, Feussner I, de Vries J (2021) The evolution of the phenylpropanoid pathway entailed pronounced radiations and divergences of enzyme families. bioRxiv 2021.05.27.445924; doi: https://doi.org/10.1101/2021.05.27.445924 Abstract
Busch T, Petersen M (2021) Identification and biochemical characterisation of tyrosine aminotransferase from Anthoceros agrestis unveils the conceivable entry point into rosmarinic acid biosynthesis in hornworts. Planta 253, 98. https://doi.org/10.1007/s00425-021-03623-2 Abstract
Marchica A, Cotrozzi L, Detti R, Lorenzini G, Pellegrini E, Petersen M, Nali C (2020) The biosynthesis of phenolic compounds is an integrated defence mechanism to prevent ozone injury in Salvia officinalis. Antioxidants 9, 1274. https://doi.org/10.3390/antiox9121274 Abstract
Wohl J, Petersen M (2020) Phenolic metabolism in the hornwort Anthoceros agrestis: 4‑coumarate CoA ligase and 4‑hydroxybenzoate CoA ligase. Plant Cell Reports 39, 1129-1141. https://doi.org/10.1007/s00299-020-02552-w Abstract
Döring AS, Cotrozzi L, Lorenzini G, Nali C, Petersen M, Pellegrini E (2020) Deciphering the role of low molecular weight antioxidants in the sensitivity of Melissa officinalis L. to realistic ozone concentrations. Industrial Crops and Products 150, 112369. DOI:10.1016/j.indcrop.2020.112369 Abstract
Wohl J, Petersen M (2020) Functional expression and characterization of cinnamic acid 4-hydroxylase from the hornwort Anthoceros agrestis in Physcomitrella patens. Plant Cell Reports 39, 597-607. DOI:10.1007/s00299-020-02517-z Abstract
Werner V, Petersen M (2019) A BAHD hydroxycinnamoyltransferase from Actaea racemosa catalyses the formation of fukinolic and cimicifugic acids. Planta 250, 475-485. DOI:10.1007/s00425-019-03181-8
Abstract
Pezeshki S, Petersen M (2018) Rosmarinic acid and related metabolites. In: Schwab W, Lange BM, Wüst M (eds) Biotechnology of Natural Products, pp 25-60, Springer, Heidelberg
Petersen M (2016) Hydroxycinnamoyltransferases in plant secondary metabolism. Phytochemistry Reviews 15, 699-727. DOI:10.1007/s11101-015-9417-1
Abstract
Poppe L, Petersen M (2016) Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom. Phytochemistry 131, 68-75. DOI:10.1016/j.phytochem.2016.09.003
Abstract
Tonelli M, Pellegrini E, D’Angiolillo F, Petersen M, Nali C, Pistelli L, Lorenzini G (2015) Ozone-elicited secondary metabolites in shoot cultures of Melissa officinalis L. Plant Cell Tissue and Organ Culture 120, 617-629. DOI:10.1007/s11240-014-0628-8
Abstract
Döring AS, Petersen M (2014) Production of caffeic, chlorogenic and rosmarinic acids in plants and suspension cultures of Glechoma hederacea. Phytochemistry Letters 10, cxi-cxvii. DOI:10.1016/j.phytol.2014.05.0122
Abstract
Döring AS, Pellegrini E, Della Bartola M, Nali C, Lorenzini G, Petersen M (2014) How do background ozone concentrations affect the biosynthesis of rosmarinic acid in Melissa officinalis? Journal of Plant Physiology 171, 35-41. DOI:10.1016/j.jplph.2013.11.005
Abstract
Döring AS, Pellegrini E, Campanella A, Trivellini A, Gennai C, Petersen M, Nali C, Lorenzini G (2014) How sensitive is Melissa officinalis to realistic ozone concentrations? Plant Physiology and Biochemistry 74, 156-164. DOI:10.1016/j.plaphy.2013.11.006
Abstract
Petersen M (2013) Rosmarinic acid – new aspects. Phytochemistry Reviews 12, 207-227. DOI:10.1007/s11101-013-9282-8
Abstract
Wolters S, Neeb M, Berim A, Schulze-Wischeler J, Petersen M, Heine A (2013) Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active site environment. Acta Crystallographica D69, 888-900. DOI:10.1107/S0907444913002874
Abstract
Hücherig S, Petersen M (2013) RNAi suppression and overexpression studies of hydroxyphenylpyruvate reductase (HPPR) and rosmarinic acid synthase (RAS) genes related to rosmarinic acid biosynthesis in hairy root cultures of Coleus blumei. Plant Cell Tissue and Organ Culture 113, 375-385. DOI:10.1007/s11240-012-0277-8
Abstract
Weitzel C, Petersen M (2011) Cloning and characterisation of rosmarinic acid synthase from Melissa officinalis L. Phytochemistry 72, 572-578. DOI:10.1016/j.phytochem.2011.01.039
Abstract
Sander M, Petersen M (2011) Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA: shikimate hydroxycinnamoyltransferase, from Coleus blumei Benth. Planta 233, 1157-1171. DOI:10.1007/s00425-011-1367-2
Abstract
Weitzel C, Petersen M (2010) Enzymes of phenylpropanoid metabolism in the important medicinal plant Melissa officinalis L. Planta 232, 731-742. DOI:10.1007/s00425-010-1206-x
Abstract
Janiak V, Petersen M, Zentgraf M, Klebe G, Heine A (2010) Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth. Acta Crystallographica D66, 593-603. DOI:10.1107/S0907444910006360
Abstract
Petersen M, Hans J, Matern U (2010) Biosynthesis of Phenylpropanoids and Related Compounds. In: Wink M (ed) Biochemistry of Plant Secondary Metabolism, Annual Plant Reviews 40, pp 182-257, Wiley-Blackwell, Chichester. DOI:10.1002/9781444320503.ch4
Abstract
Petersen M (2009) Lignane in Lebensmitteln. Praxishandbuch „Functional Food“, Behr’s Verlag
Book
Petersen M, Abdullah Y, Benner J, Eberle D, Gehlen K, Hücherig S, Janiak V, Kim KH, Sander M, Weitzel C, Wolters S (2009) Evolution of rosmarinic acid biosynthesis. Phytochemistry 70, 1663-1679. DOI:10.1016/j.phytochem.2009.05.010
Abstract
Eberle D, Ullmann P, Werck-Reichhart D, Petersen M (2008) cDNA cloning and functional characterisation of CYP98A14 and NADPH:cytochrome P450 reductase from Coleus blumei involved in rosmarinic acid biosynthesis. Plant Molecular Biology 69, 239-253. DOI:10.1007/s11103-008-9420-7
Abstract
Abdullah Y, Schneider B, Petersen M (2008) Occurrence of rosmarinic acid, chlorogenic acid and rutin in Marantaceae species. Phytochemistry Letters 1, 199-203. DOI:10.1016/j.phytol.2008.09.010
Abstract
Berim A, Ebel R, Schneider B, Petersen M (2008) UDP-glucose:(6-methoxy)podophyllotoxin 7-O-glucosyltransferase from suspension cultures of Linum nodiflorum. Phytochemistry 69, 374-381. DOI:10.1016/j.phytochem.2007.07.030
Abstract
Petersen M (2007) Current status of metabolic phytochemistry. Phytochemistry 68, 2847-2860. DOI:10.1016/j.phytochem.2007.07.029
Abstract
Berim A, Schneider B, Petersen M (2007) Methyl allyl ether formation in plants: novel S-adenosyl L-methionine:coniferyl alcohol 9-O-methyltransferase from suspension cultures of three Linum species. Plant Molecular Biology 64, 279-291. DOI:10.1007/s11103-007-9151-1
Abstract
Morant M, Schoch GA, Ullmann P, Ertunc T, Little D, Olsen DE, Petersen M, Negrel J, Werck-Reichhart D (2007) Catalytic activity, duplication and evolution of the CYP98 cytochrome P450 family in wheat. Plant Molecular Biology 63, 1-19. DOI:10.1007/s11103-006-9028-8
Abstract
Berger A, Meinhard J, Petersen M (2006) Rosmarinic acid synthase is a new member of the superfamily of BAHD acyltransferases. Planta 224, 1503-1510. DOI:10.1007/s00425-006-0393-y
Abstract
Schoch GA, Morant M, Tahir NA, Asnaghi C, Goepfert S, Lapierre C, Tax FE, Petersen M, Gang D, Ullmann P, Werck-Reichhart D (2006) The meta-hydroxylation step in the phenylpropanoid pathway: a new level of complexity in the pathway and its regulation. Environmental Chemistry Letters 4, 127-136. DOI:10.1007/s10311-006-0062-1
Abstract
Vogelsang K, Schneider B, Petersen M (2006) Production of rosmarinic acid and a new rosmarinic acid 3’-O-ß-D-glucoside in suspension cultures of the hornwort Anthoceros agrestis Paton. Planta 223, 369-373. DOI:10.1007/s00425-005-0089-8
Abstract
Berim A, Spring O, Conrad J, Maitrejean M, Boland W, Petersen M (2005) Enhancement of lignan biosynthesis in suspension cultures of Linum nodiflorum by coronalon, indanoyl-isoleucine and methyl jasmonate. Planta 222, 769-776. DOI:10.1007/s00425-005-0019-9
Abstract
Kim KH, Janiak V, Petersen M (2004) Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Molecular Biology 54, 311-323. DOI:10.1023/B:PLAN.0000036367.03056.b2
Abstract
Hölzl J, Petersen M (2003) Chemical constituents of Hypericum ssp. In: Ernst E (ed) The genus Hypericum. Taylor and Francis, London
Alfermann AW, Petersen M, Fuss E (2003) Production of natural products by plant cell biotechnology: results, problems and perspectives. In: Laimer M, Rücker W (eds) Plant Tissue Culture. 100 Years since Gottlieb Haberlandt, pp 153-166, Springer Verlag, Wien, New York
Petersen M, Simmonds MSJ (2003) Molecules of interest: Rosmarinic acid. Phytochemistry 62, 121-125. DOI:10.1016/S0031-9422(02)00513-7
Abstract
Kranz K, Petersen M (2003) ß-Peltatin 6-O-methyltransferase from suspension cultures of Linum nodiflorum. Phytochemistry 64, 453-458. DOI:10.1016/S0031-9422(03)00196-1
Abstract
Petersen M (2003) Cinnamic acid 4-hydroxyase from cell cultures of the hornwort Anthoceros agrestis. Planta 217, 96-101. DOI:10.1007/s00425-002-0960-9
Abstract
Kuhlmann S, Kranz K, Lücking B, Alfermann AW, Petersen M (2002) Aspects of cytotoxic lignan biosynthesis in suspension cultures of Linum nodiflorum. Phytochemistry Reviews 1, 37-43. DOI:10.1023/A:1015876001812
Abstract
Arroo RRJ, Alfermann AW, Medarde M, Petersen M, Pras N, Woolley JG (2002) Plant cell factories as a source for anti-cancer lignans. Phytochemistry Reviews 1, 27-35. DOI:10.1023/A:1015824000904
Abstract
Kim KH, Petersen M (2002) cDNA-cloning and functional expression of hydroxyphenylpyruvate dioxygenase (AJ309203) from cell suspension cultures of Coleus blumei. Plant Science 163, 1001-1009. DOI:10.1016/S0168-9452(02)00274-1
Abstract
Seidel V, Windhövel J, Eaton G, Alfermann AW, Arroo RRJ, Medarde M, Petersen M, Woolley JG (2002) Biosynthesis of podophyllotoxin in Linum album cell cultures. Planta 215, 1031-1039. DOI:10.1007/s00425-002-0834-1
Abstract
Schmitt J, Petersen M (2002) Influence of methyl jasmonate and coniferyl alcohol on pinoresinol and matairesinol accumulation in a Forsythia x intermedia suspension culture. Plant Cell Reports 20, 885-889. DOI:10.1007/s00299-001-0414-z
Abstract
Schmitt J, Petersen M (2002) Pinoresinol and matairesinol accumulation in a Forsythia x intermedia cell suspension culture. Plant Cell Tissue and Organ Culture 68, 91-98. DOI: 10.1023/A:1012909131741
Abstract
Petersen M (2001) Naturstoffe in Heil- und Gewürzpflanzen der Lamiaceen. DGQ Vortragstagung 2001: Gewürz- und Heilpflanzen, 103-112
Petersen M, Alfermann AW (2001) The production of cytotoxic lignans by plant cell cultures. Applied Microbiology and Biotechnology 55, 135-142. DOI:10.1007/s002530000510
Abstract
Molog GA, Empt U, Kuhlmann S, Van Uden W, Pras N, Alfermann AW, Petersen M (2001) Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans. Planta 214, 288-294. DOI:10.1007/s004250100617
Abstract
Empt U, Alfermann AW, Pras N, Petersen M (2000) The Use of Plant Cell Cultures for the Production of Podophyllotoxin and Related Lignans, Journal of Applied Botany 74, 145-150
Abstract
Petersen M, Strack D, Matern U (1999) Biosynthesis of Phenylpropanoids and Related Compounds. In: Wink M (ed) Biochemistry of Plant Secondary Metabolism, Annual Plant Reviews, Vol. 2, pp 151-221, Sheffield Academic Press, Sheffield
Abstract
Petersen M (1999) Biosynthesis and accumulation of rosmarinic acid in plant cell cultures. In: Fu TJ, Singh G, Curtis WR (eds) Plant Cell and Tissue Culture for the Production of Food Ingredients. Plenum Publishing/Kluwer Academic Publishers, Dordrecht
Szabo E, Thelen A, Petersen M (1999) Fungal elicitor preparations and methyl jasmonate enhance rosmarinic acid accumulation in in vitro-cultures of Coleus blumei. Plant Cell Reports 18, 485-489. DOI:10.1007/s002990050608
Abstract
Smollny T, Wichers H, Kalenberg S, Shahsavari A, Petersen M, Alfermann AW (1998) Accumulation of podophyllotoxin and related lignans in cell suspension cultures of Linum album. Phytochemistry 48, 975-979. DOI:10.1016/S0031-9422(97)00957-6
Abstract
Alfermann AW, Petersen M, Dombrowski K (1997): Plant Cell Cultures, in: Schweizer M (ed) Methods in Biotechnology. CRC Press
Petersen M (1997) Cytochrome P-450-dependent hydroxylation in the biosynthesis of rosmarinic acid in Coleus. Phytochemistry 45, 1165-1172. DOI:10.1016/S0031-9422(97)00135-0
Abstract
Petersen M, Van Der Straeten D, Bauw G (1995) Full-length cDNA clone from Coleus blumei (Z49150) with high similarity to cobalamine-independent methionine synthase. Plant Physiology 109, 338
Alfermann AW, Petersen M (1995) Natural product formation by plant cell biotechnology. Results and perspectives. Plant Cell Tissue and Organ Culture 43, 199-205. DOI:10.1007/BF00052176
Abstract
Petersen M, Szabo E, Meinhard J, Karwatzki B, Gertlowski C, Kempin B, Fuss E (1995) Biosynthesis and accumulation of rosmarinic acid in suspension cultures of Coleus blumei. Plant Cell Tissue and Organ Culture 43, 89-92. DOI:10.1007/BF00052161
Abstract
Alfermann AW, Petersen M, Dombrowski K (1994): Pflanzliche Zellkulturen, in: Schmauder HP (ed) Methoden der Biotechnologie. Gustav Fischer, Jena
Petersen M (1994) Coleus spp.: In vitro culture and the production of forskolin and rosmarinic acid, in: Bajaj YPS (ed) Biotechnology in Agriculture and Forestry, Medicinal and Aromatic Plants VI, pp 69-92, Springer, Berlin, Heidelberg
Petersen M, Häusler E, Meinhard J, Karwatzki B, Gertlowski C (1994) The biosynthesis of rosmarinic acid in suspension cultures of Coleus blumei. Plant Cell Tissue and Organ Culture 38, 171-179. DOI:10.1007/BF00033875
Abstract
Petersen M, Alfermann AW (1993) Plant Cell Cultures, in: Rehm HJ, Reed G (eds) Biotechnology, Vol. 1, pp 577-614, Verlag Chemie (VCH), Weinheim
Petersen M, Metzger JW (1993) Identification of the reaction products of rosmarinic acid synthase from cell cultures of Coleus blumei by ion spray mass spectrometry and tandem mass spectrometry. Phytochemical Analysis 4, 131-134. DOI:10.1002/pca.2800040310
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Petersen M (1993) Purification of rosmarinic acid synthase from cell cultures of Coleus blumei. Planta 191, 18-22. DOI:10.1007/BF00240891
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Häusler E, Petersen M, Alfermann AW (1993) Isolation of protoplasts and vacuoles from cell suspension cultures of Coleus blumei Benth. Plant Cell Reports 12, 510-512. DOI:10.1007/BF00236097
Abstract
Gertlowski C, Petersen M (1993) Influence of the carbon source on growth and rosmarinic acid production in suspension cultures of Coleus blumei. Plant Cell Tissue and Organ Culture 34, 183-190. DOI:10.1007/BF00036100
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Petersen M, Häusler E, Karwatzki B, Meinhard J (1993) Proposed biosynthetic pathway for rosmarinic acid in cell cultures of Coleus blumei Benth. Planta 189, 10-14. DOI:10.1007/BF00201337
Abstract
Petersen M, Dombrowski K, Gertlowski C, Häusler E, Karwatzki B, Meinhard J, Alfermann AW (1992) The use of plant cell cultures to study natural product biosynthesis. In: Oono K, Hirabayashi T, Kikuchi S, Handa H, Kajiwara K (eds) Plant Tissue Culture and Gene Manipulation for Breeding and Formation of Phytochemicals, pp 297-310. National Institute for Agrobiological Resources (NIAR), Tsukuba, Japan
Petersen M, Dombrowski K, Alfermann AW (1992) Useful enzymes from plant cell and organ cultures. In: Servi S (ed) Microbial Reagents in Organic Synthesis, pp 441-453. NATO ASI Series C Vol. 381. Kluwer Academic Publishers, Dordrecht, Boston, London
Petersen M (1991) Characterization of rosmarinic acid synthase from cell cultures of Coleus blumei. Phytochemistry 30, 2877-2881. DOI:10.1016/S0031-9422(00)98217-7
Abstract
Pabsch K, Petersen M, Rao NN, Alfermann AW, C. Wandrey (1991) Chemo-enzymatic synthesis of rosmarinic acid. Recueil des Travaux Chimiques des Pays-Bas 110, 199-205. DOI:10.1002/recl.19911100512
Abstract
Häusler E, Petersen M, Alfermann AW (1991) Hydroxyphenylpyruvate reductase from cell suspension cultures of Coleus blumei Benth. Zeitschrift für Naturforschung 46c, 371-376. DOI:10.1515/znc-1991-5-607
Abstract
Petersen M, Seitz HU, Alfermann AW (1989) Digitoxin 12ß-hydroxylase, a cytochrome P-450-dependent enzyme from cell cultures of Digitalis lanata Ehrh., in: Kurz WGW (ed) Primary and Secondary Metabolism of Plant Cell Cultures II, pp 110-116. Springer, Heidelberg
Petersen M, Alfermann AW, Seitz HU (1988) Characterization and immobilization of digitoxin 12ß-hydroxylase from cell cultures of Digitalis lanata EHRH.. In: Pais MSS, Mavituna F, Novais JM (eds) Plant Cell Biotechnology, NATO ASI Series H Vol. 18, pp 365-371. Springer, Berlin
Petersen M, Alfermann AW (1988) Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: Hydroxyphenylpyruvate reductase and rosmarinic acid synthase. Zeitschrift für Naturforschung 43c, 501-504. DOI:10.1515/znc-1988-7-804
Abstract
Petersen M, Seitz HU (1988) Reconstitution of cytochrome P-450-dependent digitoxin 12ß-hydroxylase from cell cultures of foxglove (Digitalis lanata EHRH.). Biochemical Journal 252, 537-543. DOI:10.1042/bj2520537
Abstract
Petersen M, Seitz HU, E. Reinhard (1988) Characterization and localization of digitoxin 12ß-hydroxylase from cell cultures of Digitalis lanata EHRH. Zeitschrift für Naturforschung 43c, 199-206. DOI:10.1515/znc-1988-3-409
Abstract
Petersen M, Alfermann AW, Reinhard E, Seitz HU (1987) Immobilization of digitoxin 12ß-hydroxylase, a cytochrome P-450-dependent enzyme from cell cultures of Digitalis lanata EHRH. Plant Cell Reports 6, 200-203. DOI:10.1007/BF00268479
Abstract
Petersen M, Seitz HU (1986) UDP-glucose:cyanidin 3-O-glucosyltransferase in anthocyanin-containing cell cultures from Daucus carota L. Journal of Plant Physiology 125, 383-390. DOI:10.1016/S0176-1617(86)80001-3
Abstract
Hopp W, Hinderer W, Petersen M, Seitz HU (1985) Anthocyanin-containing vacuoles isolated from protoplasts of Daucus carota cell cultures. In: Pilet PE (ed) The Physiological Properties of Plant Protoplasts, pp 122-132. Springer, Berlin, Heidelberg
Petersen M, Seitz HU (1985) Cytochrome P-450-dependent digitoxin 12ß-hydroxylase from cell cultures of Digitalis lanata. FEBS Letters 188, 11-14. DOI:10.1016/0014-5793(85)80865-6
Abstract
Hinderer W, Petersen M, Seitz HU (1984) Inhibition of flavonoid biosynthesis by gibberellic acid in cell suspension cultures of Daucus carota L. Planta 160, 544-549. DOI:10.1007/BF00411143
Abstract