Hauptinhalt

Publikationen

2022

Structural and Functional Insight into the Mechanism of Bacillus subtilis 6S-1 RNA Release from RNA Polymerase
Ganapathy S, Hoch PG, Lechner M, Bussiek M,, Hartmann RK
Non-Coding RNA 2022, 8, 20.

2021

Identification and characterization of short leader and trailer RNAs synthesized by the Ebola virus RNA polymerase
Bach S, Demper JC, Klemm P, Schlereth J, Lechner M, Schoen A, Kämper L, Weber F, Becker S, Biedenkopf N, Hartmann RK
PLoS Pathog. 2021 Oct 26;17(10):e1010002. doi: 10.1371/journal.ppat.1010002. eCollection 2021 Oct. PMID: 34699554

Insights into 6S RNA in lactic acid bacteria (LAB)
Cataldo PG, Klemm P, Thüring M, Saavedra L, Hebert EM, Hartmann RK, Lechner M
BMC Genom Data. 2021 Sep 3;22(1):29. doi: 10.1186/s12863-021-00983-2. PMID: 34479493

Dual role of a (p)ppGpp- and (p)ppApp-degrading enzyme in biofilm formation and interbacterial antagonism
W. Steinchen, S. Ahmad, M. Valentini, K. Eilers, M. Majkini, F. Altegoer, M. Lechner, A. Filloux, JC. Whitney, G. Bange
Mol Microbiol. 2021 Jan 15. doi: 10.1111/mmi.14684

6S-2 RNA deletion in the undomesticated B. subtilis strain NCIB 3610 causes a biofilm derepression phenotype
M. Thüring, S. Ganapathy, M. AC. Schlüter, M. Lechner, R. K. Hartmann
RNA Biol. 2021 Jan;18(1):79-92. doi: 10.1080/15476286.2020.1795408

2020

The two paralogous kiwellin proteins KWL1 and KWL1-b from maize are structurally related and have overlapping functions in plant defense
F. Altegoer, P. Weiland, PI Giammarinaro, SA Freibert, L. Binnebesel, X. Han, A. Lepak, R. Kahmann, M. Lechner, G. Bange
J Biol Chem. 2020 Jun 5;295(23):7816-7825. doi: 10.1074/jbc.RA119.012207. Epub 2020 Apr 28.

Tol-Pal System and Rgs Proteins Interact to Promote Unipolar Growth and Cell Division in Sinorhizobium meliloti
E. Krol, HCL Yau, M. Lechner, S. Schäper, G. Bange, W. Vollmer, A. Becker
mBio. 2020 Jun 30;11(3):e00306-20. doi: 10.1128/mBio.00306-20.

Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway
M. Aznaourova, H. Janga, S. Sefried, A. Kaufmann, J. Dorna, S. M. Volkers, P. Georg, M. Lechner, J. Hoppe, S. Dökel, N. Schmerer, A. D. Gruber, U. Linne, S. Bauer, L. E. Sander, B. Schmeck, L. Schulte
Proc Natl Acad Sci U S A. 2020 Apr 2. pii: 201920393. doi: 10.1073/pnas.1920393117

2019

Sequence and structural properties of circular RNAs in the brain of nurse and forager honeybees (Apis mellifera)
C. Thölken, M. Thamm, C. Erbacher, M. Lechner
BMC Genomics. 2019 Jan 25; 20(1):88. doi: 10.1186/s12864-018-5402-6

2017

Minimal and RNA-free RNase P in Aquifex aeolicus
A. I. Nickel, B. N. Wäber, M. Gößringer, M. Lechner, U. Linne, U. Tothc, W. Rossmanith, R. K. Hartmann
PNAS. 2017 Oct EE publication. doi: 10.1073/pnas.1707862114

6S RNA in Rhodobacter sphaeroides: 6S RNA and pRNA transcript levels peak in late exponential phase and gene deletion causes a high salt stress phenotype
D. Elkina, L. Weber, M. Lechner, O. Burenina, A. Weisert, E. Kubareva, R. K. Hartmann, G. Klug
RNA Biol. 2017 Jul 10:1-11. doi: 10.1080/15476286.2017.1342933

Protein-only RNase P function in Escherichia coli: viability, processing defects and differences between PRORP isoenzymes
M. Gößringer, M. Lechner, N. Brillante, C. Weber, W. Rossmanith, R. K. Hartmann
Nucleic Acids Res. 2017 Jul 7;45(12):7441-7454. doi: 10.1093/nar/gkx405.

2016

The conserved dcw gene cluster of R. sphaeroides is preceded by an uncommonly extended 5' leader featuring the sRNA UpsM
L. Weber, C. Thoelken, M. Volk, B. Remes, M. Lechner, G. Klug
PLoS One. 2016 Nov 1;11(11):e0165694. doi: 10.1371/journal.pone.0165694. eCollection 2016.

A genomic view of food-related and probiotic enterococcus strains
J. Bonacina, N. Suárez, R. Hormigo, S. Fadda, M. Lechner, L. Saavedra
DNA Res. 2017 Feb 1;24(1):11-24. doi: 10.1093/dnares/dsw043.

Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems
P. Kanrai, A. Mostafa, R. Madhugiri, M. Lechner, E. Wilk, K. Schughart, L. Ylösmäki, K. Saksela, J. Ziebuhr, S. Pleschka
J Gen Virol. 2016 Sep;97(9):2135-48. doi: 10.1099/jgv.0.000542. Epub 2016 Jul 12.

Bacillus subtilis 6S-2 RNA serves as a template for short transcripts in vivo
P. G. Hoch, J. Schlereth, M. Lechner, R. K. Hartmann
RNA. 2016 Apr;22(4):614-22. doi: 10.1261/rna.055616.115. Epub 2016 Feb 12.

Positive selection or free to vary? Assessing the functional significance of sequence change using molecular dynamics
J. R. Allison, M. Lechner, M. P. Hoeppner, A. M. Poole
PLoS One. 2016 Feb 12;11(2):e0147619. doi: 10.1371/journal.pone.0147619. eCollection 2016.

2015

Distribution of Ribonucleoprotein and Protein-only RNase P in Eukarya
Lechner, M and Rossmanith, W and Hartmann, R K and Thölken, C and Gutmann, B and Giegé, P and Gobert, A
Mol Biol Evol. 2015 Dec;32(12):3186-93. doi: 10.1093/molbev/msv187. Epub 2015 Sep 3.

Structural and mechanistic characterization of 6S RNA from the hyperthermophilic bacterium Aquifex aeolicus
Köhler, K and Duchardt-Ferner, E and Lechner, M and Damm, K and Hoch, P G and Salas, M and Hartmann, R K
Biochimie. 2015 Oct;117:72-86. doi: 10.1016/j.biochi.2015.03.004. Epub 2015 Mar 11.

Phylogenomics with paralogs
Hellmuth, M and Wieseke, N and Lechner, M and Lenhof, HP and Middendorf, M and Stadler, P F
Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2058-63. doi: 10.1073/pnas.1412770112. Epub 2015 Feb 2.

2014

Mechanistic comparison of Bacillus subtilis 6S-1 and 6S-2 RNAs - commonalities and differences
Burenina, O Y and Hoch, P G and Damm, K and Salas, M and Zatsepin, T S and Lechner, M and Oretskaya, T S and Kubareva, E A and Hartmann, R K
RNA. 2014 Mar;20(3):348-59. doi: 10.1261/rna.042077.113. Epub 2014 Jan 24.

Orthology Detection Combining Clustering and Synteny for Very Large Data Sets
Lechner, M and Hernandez-Rosales, M and Doerr, D and Wieseke, N and Thévenin, A and Stoye, J and Hartmann, R K and Prohaska, S J and Stadler, P F
PLoS One. 2014 Aug 19;9(8):e105015. doi: 10.1371/journal.pone.0105015. eCollection 2014.

When belowground rumbles: plant‘s interactions with antagonists are robust to earthquake-induced shifts in the belowground environment
Gamlen-Greene, R and Clemens, J and Morgenroth J, and Lechner, M and Godsoe, W
New Zealand Journal of Ecology (2014) 38(1): 39-44

Genomewide comparison and novel ncRNAs of Aquificales
Lechner, M and Nickel, A I and Wehner, S and Riege, K and Wieseke, N and Beckmann, B M and Hartmann, R K and Marz, M
BMC Genomics. 2014 Jun 25;15:522. doi: 10.1186/1471-2164-15-522.

2013 und früher

Pomago: Multiple Genome-wide Alignment Tool for Bacteria
Wieseke, N and Lechner, M and Ludwig, M and Marz, M
Bioinformatics Research and Applications, Lecture Notes in Computer Science. 2013; 7875(1) pp 249-260

The Correlation of Genome Size and DNA Methylation Rate in Metazoans
Lechner, M and Marz, M and Ihling, C and Sinz, A and Stadler, P F and Krauss, V
Theory Biosci. 2013 Mar;132(1):47-60. doi: 10.1007/s12064-012-0167-y. Epub 2012 Nov 7.

Genetic Characterization of Tribeč virus and Kemerovo virus, two tick-transmitted human-pathogenic Orbiviruses
Dilcher, M and Hasib, L and Lechner, M and Wieseke, N and Middendorf, M and Marz, M and Koch, A and Spiegel, M and Dobler, G and Hufert, F T and Weidmann, M
Virology. 2012 Feb 5;423(1):68-76. doi: 10.1016/j.virol.2011.11.020. Epub 2011 Dec 20.

Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Lechner, M and Findeiss, S and Steiner, L and Marz, M and Stadler, P F and Prohaska, S J
BMC Bioinformatics. 2011 Apr 28;12:124. doi: 10.1186/1471-2105-12-124.