Hauptinhalt
Publikationen
Originalveröffentlichungen
2024
Gemmecker Y., Winiarska A., Hege D., Kahnt J., Seubert A., Szaleniec M., Heider J. (2024) A pH-dependent shift of redox cofactor specificity in a benzyl alcohol dehydrogenase of Aromatoleum aromaticum EbN1. Appl. Microbiol. Biotechnol. submitted.
Pöhl S., Giacomelli G., Meyer F., Kleeberg V., Cohen E. J., Biboy J., Rosum J., Glatter T., Vollmer W., Beeby M., van Teeseling M. C. F., Heider J., Brankamp M. & Thanbichler M. (2024) An outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in Rhodospirillum rubrum. Nature Commun. submitted.
Szaleniec M., Oleksy G., Sekuła A., Aleksic I., Pietras R., Sarewicz M., Krämer K., Pierik A. J., Heider J. (2024) Modeling the initiation phase of the catalytic cycle in the glycyl-radical enzyme benzylsuccinate synthase. Journal Phys. Chem. B 128, 24, 5823 - 5839. Doi:10.1021/acs.jpcb.4c01237
Andrys-Olek J., Kluza A., Tataruch M., Heider J., Korecki J., Borowski T.M. (2024) Bacteria at work – Experimental and theoretical studies reveal the catalytic mechanism of ectoine synthase. Chemistry Europe Journal. Volume 30, e202304163. DOI:10.1002/chem.202304163
Mock J., Schühle K., Linne U., Mock M. & Heider J. (2024) A synthetic pathway for the production of benzylsuccinate in Escherichia coli. MDPI Molecules 29(2), 415. DOI:10.3390/29020415
2023
Luo S. Adam D. Giaveri S., Barthel S., Cestellos-Blanco S., Hege D., Paczia N., Castañeda-Losada L., Klose M., Arndt F., Heider J. & Erb T. J. (2023) ATP production from electricity with a new-to-nature electrobiological module. Joule 7, 1745-1758. DOI:10.1016/j.joule.2023.07.012
Winiarska A., Ramírez-Amador F., Hege D., Gemmecker Y., Prinz S., Hochberg G., Heider J., Szaleniec M., Schuller J. M. (2023) A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire. Science Adv 9, eadg6689. DOI: 10.1101/2023.01.23.525143
Kalimuthu P., Hege D., Winiarska A., Gemmecker Y., Szaleniec M., Heider J., Bernhardt P. V. (2023) Electrocatalytic aldehyde oxidation by a tungsten dependent aldehyde oxidoreductase from Aromatoleum aromaticum. Chemistry European Journal. DOI:10.1002/202203072
Andrys-Olek J., Heider J., Borowski T. (2023) Molecular Dynamics simulations for the Michaelis complex of Ectoine Synthase (EctC). Catalysts 13, 124. DOI: 10.3390/catal13010124
Shalygin M. G., Kozlova A.A., Heider J., Sapegin D.A., Netrusov A.A. & Teplyakov (2023) Polymeric membranes for vapor-base concentrating volatile organic products from biomass processing. Membranes Membr Technol 5, 65-80. DOI://10.1134/S2517751623010055
2022
Lo H.-Y., Matinéz-Lavanchy P., Goris T., Heider J., Boll M., Kaster A.-K. & Müller J. A. (2022) IncP-type plasmids carrying genes for antibiotic resistance or for aromatic compound degradation are prevalent in sequenced Aromatoleum and Thauera strains. Environ. Microbiol. 24, 6411-6425. DOI: 10.1111/1462-2920.16262
Chistyakova P. A., Chistyakov A. V., Nikolaev S. A., Bagdatov R. A., Tsodikov M. V., Heider J. & Netrusov A. I. (2022) Conversion of ethanol and fusel oils over Au-M/MFI/Al2O3 calalysts. Petrol. Chem. 62, 1107-1125. DOI: 10.1134/S0965544122090018
Steinhilper R., Höff G., Heider J., Murphy B. J. (2022) Structure of the membrane-bound formate hydrogen lyase complex from Escherichia coli. Nature Comm. 13, 5395. DOI: 10.1101/2022.03.21.484881
Winiarska A., Hege D., Gemmecker Y., Kryściak-Czerwenka J., Seubert A., Heider J., Szaleniec M. (2022) A tungsten enzyme using hydrogen as an electron donor to reduce carboxylic acids and NAD+. ACS Catalysis 12, 8707-8717. DOI: 10.1021/acscatal.2c02147
Weidenweber S., Schühle K., Lippert M.-L., Mock J., Seubert A., Demmer U., Ermler U. & Heider J. (2022) Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyses the final step of anaerobic toluene metabolism. FEBS J. 289, 5599-5616. DOI: 10.1111/febs.16443
von Horsten S., Lippert M.-L., Geisselbrecht Y., Schühle K., Schall I., Essen L.-O., Heider J. (2022) Inactive pseudoenzyme subunits in heterotetrameric BbsCD, a novel short-chain alcohol dehydrogenase involved in anaerobic toluene degradation. FEBS J. 289, 1023-1042. DOI: 10.1111/febs.16216
Hagel C., Blaum B., Friedrich T. & Heider J. (2022) Characterisation of the redox centers of ethylbenzene dehydrogenase. J. Biol. Inorg. Chem. 27, 143-154. DOI: 10.1007/s00775-021-01917-0
2021
Andrys J., Heider J., Borowski T. (2021) Comparison of different approaches to derive classical bonded force-field parameters for a transition metal cofactor. A case study for non-heme iron site of ectoine synthase. Theor. Chem. Acc. 140, 115. DOI: 10.1007/s00214-021-02796-z
Schühle K., Saft M., Vögeli B., Erb T. J., Heider J. (2021) Benzylmalonyl-CoA dehydrogenase, an enzyme involved in bacterial auxin degradation. Arch Microbiol. accepted. DOI: 10.21203/rsa.3.5s-466161/v1
Salii I., Szaleniec M., Alhaj Zein A., Seyhan D., Sekula A., Schühle K., Kaplieva-Dudek I., Linne U., Meckenstock R. U. & Heider J. (2021) Determinants for substrate recognition in the glycyl radical enzyme benzylsuccinate synthase revealed by targeted mutagenesis. ACS Catal.11, 3361-3370. DOI: 10.1021/acscatal.0c04954
2020
Borowiecki P., Teltycka N., Tataruch M., Żądło-Dobrowolska A., Reiter T., Schühle K., Heider J., Szaleniec M., Kroutil W. (2020) Biocatalytic asymmetric reduction of γ‐keto esters to access optically active γ‐aryl‐γ‐butyrolactones. Adv. Synth. Catal. 362, 2012-2029. DOI: 10.1002/adsc.201901483
2019
Vogt M. S., Kölzer S., Schühle K., Peschke P., Schall I., Chowdhury N. P., Buckel W., Kleinsorge D., Essen L.-O., Heider J. (2019) Diversity of electron transferring flavoproteins: structure and function of a paralogue involved in anaerobic toluene metabolism. J. Bacteriol. 201, 00326-19. DOI: 10.1128/JB.00326-19
Schmitt G., Saft M., Arndt F., Kahnt J., Heider J. (2019) Two different quinohemoprotein amine dehydrogenases initiate anaerobic degradation of aromatic amines in Aromatoleum aromaticum EbN1. J. Bacteriol. 201, e00281-19. DOI: 10.1128/JB.00281-19
Arndt F., Schmitt G., Winiarska A., Saf M.t, Seubert A., Kahnt J., Heider J. (2019) Characterisation of an aldehyde oxidoreductase from the mesophilic bacterium Aromatoleum aromaticum, a member of a new subfamily of tungsten-containing enzymes. Front. Microbiol. 10, 71. DOI: 10.3389/fmicb.2019.00071
Czech L., Höppner A., Kobus S., Seubert A., Riclea R., Dickschat J. S., Heider J., Smits S. H. J. & Bremer E. (2019) Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis. Nature Sci. Rep. 9, 364. DOI: 10.1038/s41598-018-36247-w
Özcan A., Pausch P., Linden A., Wulf A., Schühle K., Heider J., Urlaub H., Heimerl T., Bange G, and Randau L. (2019) Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiol. 4, 89-96. DOI: 10.1038/s41564-018-0274-8
2018
León M. J., Hoffmann T., Sánchez-Porro C., Heider J., Ventosa A. & Bremer E. (2018) Compatible solute synthesis and import by the moderate halophile Spiribacter salinus: physiology and genomics. Front. Microbiol. 9, 108. DOI: 10.3389/fmicb.2018.00108
2017
Schulz A., Hermann L., Freibert S.-A., Bönig T., Hoffmann T., Ricela R., Dickschat J. S., Heider J. Bremer E. (2017) Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues. Environ. Microbiol. 19, 4599-4619. DOI: 10.1111/1462-2920.13924
Warkentin E., Weidenweber S., Schühle K., Demmer U., Heider J. & Ermler U. (2017) A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins 85, 2017-2023. DOI: 10.1002/prot.25355
Schmitt G., Arndt F., Kahnt J., Heider J. (2017) Adaptations to a loss-of-function mutation in the betaproteobacterium Aromatoleum aromaticum: recruitment of alternative enzymes for anaerobic phenylalanine degradation. J. Bacteriol. 199, e00383-17. DOI: 10.1128/JB.00383-17
Schulz A., Stöveken N., Binzen I. M., Hoffmann T., Heider J. Bremer E. (2017) Feeding on compatible solutes: a substrate-induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR. Environ. Microbiol. 19, 926-946. DOI: 10.1111/1462-2920.13414
Weidenweber S., Schühle K., Demmer U., Warkentin E., Ermler U. & Heider J. (2017) Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Nature Sci. Rep. 7, 39674. DOI: 10.1038/srep39674
2016
Schühle K., Nies J. & Heider J. (2016) An indoleactate-CoA ligase and a phenylsuccinate CoA-transferase involved in anaerobic indoleacteate metabolism. Environ. Microbiol. 18, 3120-3132. DOI: 10.1111/1462-2920.13347
Seyhan D., Friedrich P., Szaleniec M., Hilberg M., Golding B. T., Buckel W. & Heider J. (2016) Elucidating the Stereochemistry of Enzymatic Benzylsuccinate Synthesis with Chirally Labeled Toluene. Angew. Chemie Int. Ed. 55, 11664-11667. DOI: 10.1002/anie.201605197
Seyhan D., Friedrich P., Szaleniec M., Hilberg M., Golding B. T., Buckel W. & Heider J. (2016) Stereochemischer Verlauf der enzymatischen Synthese von Benzylsuccinat mit chiral markiertem Toluol. Angew. Chemie 128, 11832-11835. DOI: 10.1002/ange.201605197
Szaleniec M. & Heider J. (2016) Modeling of the reaction mechanism of enzymatic radical C-C coupling by benzylsuccinate synthase. Int. J. Mol. Sci. 17,514. DOI: 10.3390/ijms17040514
Widderich N., Kobus S., Hoeppner A., Riclea R., Seubert A., Dickschat J., Heider J., Smits S. H. J. & Bremer E. (2016) Biochemistry and crystal structure of the ectoine synthase: a metal-containing member of the cupin superfamily. PLoS One, 11, e0151285. eCollection 2016. DOI: 10.1371/journal.pone.0151285
Muhr E., Leicht O., González Sierra S., Thanbichler M. & Heider J. (2016) A fluorescent bioreporter for acetophenone and 1-phenylethanol derived from a specifically induced catabolic operon. Front. Microbiol. 6, 1561. DOI: 10.3389/fmicb.2015.01561
Widderich N., Czech L., Elling F. J., Könneke M., Stöveken N., Pittelkow M., Riclea R., Dickschat J., Heider J. & Bremer E. (2016) Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus. Environ. Microbiol. 18, 1227-1248. DOI: 10.1111/1462-2920.13156
2015
Dudzik A., Snoch W., Borowiecki P., Opalinska-Piskorz J., Witko M., Heider J., Szaleniec M. (2015) Asymmetric reduction of ketones and β-keto esters by (S)-1-phenylethanol dehydrogenase from denitrifying bacterium Aromatoleum aromaticum. Appl. Microbiol. Biotechnol. 99, 5055-5069. DOI: 10.1007/s00253-014-6309-z
Muhr E., Schühle K., Clermont L., Sünwoldt K., Kleinsorge D., Seyhan D., Kahnt J., Schall I., Cordero P. R., Schmitt G. & Heider J. (2015) Enzymes of anaerobic ethylbenzene and p-ethylphenol catabolism in Aromatoleum aromaticum: differentiation and differential induction. Arch. Microbiol. 197, 1051-1062. DOI: 10.1111/1462-2920.13414
Kalimuthu P., Heider J., Knack D. & Bernhardt P. V. (2015) Electrocatalytic hydrocarbon hydroxylation by ethylbenzene dehydrogenase from Aromatoleum aromaticum. J. Phys. Chem. B 119, 3456-3463. DOI: 10.1012/jp512562k
2014
Debnar-Daumler C., Seubert A., Schmitt G. & Heider J. (2014) Simultaneous involvement of a tungsten-containing aldehyde:ferredoxin oxidoreductase and a phenylacetaldehyde dehydrogenase in anaerobic phenylalanine metabolism. J. Bacteriol. 196, 483-492. DOI: 10.1128/JB.00980-13
Szaleniec M., Dudzik A., Kozik B., Borowski T., Heider J. & Witko M. (2014) Mechanistic basis for the enantioselectivity of anaerobic hydroxylation of alkylaromatic compounds by ethylbenzene dehydrogenase. J. Inorgan. Biochem. 139, 9-20. DOI: 10.1016/j.jinorgbio.2014.05.006
Tataruch M., Bryjak J., Nowak P., Knack D., Czerniak A., Liesiene J., Heider J. & Szaleniec M. (2014) Suitability of the hydrocarbon-hydroxylating molybdenum-enzyme ethylbenzene dehydrogenase for industrial chiral alcohol production. J. Biotechnol. 192, 400-409. DOI: 10.1016/j.jbiotec.2014.06.021
Widderich N., Höppner A., Pittelkow M., Heider J., Smits S. H. J. & Bremer E. (2014) Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms. PLOS One 9, e93809. DOI: 10.1371/journal.pone.0093809
2013
Dudzik A., Kozik B., Tataruch M., Wójcik A., Knack D., Borowski T., Heider J., Witko M. & Szaleniec M. (2013) The reaction mechanism of chiral hydroxylation of p-OH and p-NH2 substituted compounds by ethylbenzene dehydrogenase. Can J. Chem. 91, 775-786. DOI: 10.1139/cjc-2012-0504
Knack D. H, Marshall J. L., Harlow G. P., Dudzik A., Szaleniec M., Liu S.-Y. & Heider J. (2013) BN/CC-isosterische Verbindungen als Enzyminhibitoren: Hemmung der Hydroxylierung von Ethylbenzol durch N - und B -Ethyl-1,2-azaborin als nichtkonvertierbare Substratanaloga.,Angew. Chemie 125, 2660 –2662. DOI: org/10.1002/ange.201208351
Knack D. H, Marshall J. L., Harlow G. P., Dudzik A., Szaleniec M., Liu S.-Y. & Heider J. (2013) BN/CC isosteric compounds as enzyme inhibitors: N- and B-ethyl-1,2-azaborine inhibit ethylbenzene hydroxylation as nonconvertible substrate analogs. Angew. Chemie Int. Ed. 52, 2599-2601. DOI: 10.1002/anie.201208351
Kümmel S., Kuntze K., Vogt C., Boll M., Heider J. & Richnow H. H. (2013) Evidence for benzylsuccinate synthase subtypes by stable isotope tools. J. Bacteriol. 195, 4660-4667. DOI: 10.1128/JB.00477-13
2012
Ebenau-Jehle C., Thomas M., Scharf G., Kockelkorn D., Knapp B., Schühle K., Heider J. & Fuchs G. (2012) Anaerobic Metabolism of Indoleacetate. J. Bacteriol. 194, 2894-2903. DOI: 10.1128/JB.00250-12
Hilberg M., Pierik A. J., Bill E., Friedrich T., Lippert M.-L. & Heider J. (2012) Identification of FeS-clusters in the glycyl radical enzyme benzylsuccinate synthase via EPR and Mössbauer spectroscopy. J. Biol. Inorg. Chem. 17, 49-56. DOI: 10.1007/s0075-011-0828-1
Knack D., Hagel C., Szaleniec M., Dudzik A., Salwinski A. & Heider J. (2012) Substrate and inhibitor spectrum of ethylbenzene dehydrogenase: implications on application potential and enzyme mechanism. Appl. Environ. Microbiol. 78, 6475-6482. DOI: 10.1128/AEM.01551-12
Schühle K. & Heider J. (2012) Acetone and butanone metabolism of the denitrifying bacterium “Aromatoleum aromaticum” demonstrates novel biochemical properties of an ATP-dependent aliphatic ketone carboxylase. J. Bacteriol. 194, 131-141. DOI: 10.1128/JB.05898-11
Szaleniec M., Salwinski A., Borowski T., Heider J. & Witko M. (2012) Quantum chemical modeling studies of ethylbenzene dehydrogenase activity. Intl. J. Quant. Chem. 112, 1990-1999. DOI: org/10.1002/qua.23143
2011
Rabus R., Jarling R., Lahme S., Kühner S., Heider J., Widdel F. & Wilkes H. (2011) Co-metabolic conversion of toluene in anaerobic n-alkane-degrading bacteria. Environ. Microbiol. 13, 2576-2586. DOI: 10.1111/j.1462-2920.2011.02529.x
Stöveken N., Pittelkow M., Sinner T., Jensen R. A., Heider J. & Bremer E. (2011) A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501. J. Bacteriol. 193, 4456-4468. DOI: 10.1128JB.00345-11
2010
Jobst B., Schühle K., Linne U. & Heider J. (2010) ATP-dependent carboxylation of acetophenone by a novel type of carboxylase. J. Bacteriol. 192, 1387-1394. DOI: 10.1128/JB.01423-09
Müller F. D., Treuner-Lange A., Heider J., Huntley S. M., Higgs P. I. (2010) Global transcriptome analysis of spore formation in Myxococcus xanthus reveals a locus necessary for cell differentiation. BMC Genomics 11, 264. DOI: 10.1186/1471-2164-11-264
Szaleniec M., Borowski T., Schühle K., Witko M. & Heider J. (2010) Ab initio modelling of ethylbenzene dehydrogenase reaction mechanism. J. Amer. Chem. Soc. 132, 6014-6024. DOI: 10.1021/ja907208k
2008
Grundmann O., Behrends A., Rabus R., Amann J., Halder T., Heider J. & Widdel F. (2008) Genes encoding a tentative enzyme for anaerobic activation of n-alkanes in the denitrifying bacterium, strain HxN1. Environ. Microbiol. 10, 376-385. DOI: 10.1111/j.1462-2920.2007.01458.x
Szaleniec M., Witko M & Heider J. (2008) Quantum chemical modelling of C-H cleavage mechanism in oxidation of ethylbenzene and its derivates by ethylbenzene dehydrogenase. J. Molec. Catal. A, 286, 128-136. DOI: org./10.1016/j.molcata.2008.02.016
2007
Szaleniec M., Hagel C., Menke M., Nowak P., Witko M. & Heider J. (2007) Kinetics and mechanism of oxygen-independent hydrocarbon-hydroxylation by ethylbenzene dehydrogenase. Biochemistry 46, 7637-7646. DOI: 10.1021/bi700633c
2006
Höffken H. W., Duong M., Friedrich T., Breuer M., Hauer B., Reinhardt R., Rabus R., Heider J. (2006) Crystal structure and enzyme kinetics of the (S)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain EbN1. Biochemistry, 45, 82-93. DOI: 10.1021/bi051596b
Kloer D. P., Hagel C., Heider J. & Schulz, G. E. (2006) Crystal Structure of Ethylbenzene dehydrogenase from Aromatoleum aromaticum. Structure 14, 1377-1388. DOI: 10.1016j.str.2006.07.001
2005
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F. & Reinhard R. (2005) The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1. Arch. Microbiol. 183, 27-36. DOI: 10.1007/s00203-004-0742-9
2004
Kube M., Heider J., Amann J., Hufnagel P., Kühner S., Beck A., Reinhardt R. & Rabus R. (2004) Genes involved in the anaerobic degradation of toluene in a denitrifying bacterium, strain EbN1. Arch. Microbiol. 181, 182-194. DOI: 10.1007/s00203-003-0627-3
Verfürth K., Pierik A. J., Leutwein C., Zorn S. & Heider J. (2004) Substrate specificities and electron paramagnetic resonance properties of benzylsuccinate synthases in anaerobic toluene- and m-xylene-metabolism. Arch. Microbiol. 181, 155-162. DOI: 10.1007/s00203-003-0642-4
2003
Duboc-Toia C., Hassan A. K., Mulliez E., Ollagnier-de Choudens S., Fontecave M., Leutwein C. & Heider J. (2003) Very high field EPR studies of glycyl radical enzymes. J. Amer. Chem. Soc. 125, 38-39. DOI: 10.1021/ja026690j
Szaleniec M., Jobst B. & Heider J. (2003) Ethylbenzene dehydrogenase: oxidation of hydrocarbons without oxygen. Ann. Pol. Chem.Soc. 2003, 240-245.
2002
Hermuth K., Leuthner B. & Heider J. (2002) Operon structure and expression of the genes for benzylsuccinate synthase in Thauera aromatica strain K172. Arch. Microbiol. 177, 132-138. DOI: 10.1007/s00203-001-0375-1
Leutwein C. & Heider J. (2002) (R)-Benzylsuccinyl-CoA dehydrogenase from Thauera aromatica: a new acyl-CoA dehydrogenase involved in anaerobic toluene catabolism. Arch. Microbiol. 178, 517-524. DOI: 10.1007/s00203-002-0484-5
Mohamed M. E., Ismail W., Heider J. & Fuchs G (2002) Aerobic metabolism of phenylacetic acids in Azoarcus evansii. Arch. Microbiol. 178, 180-192. DOI: 10.1007/s00203-002-0438-y
2001
Kniemeyer O. & Heider J. (2001) Ethylbenzene dehydrogenase, a novel hydrocarbon-oxidising molybdenum/iron-sulfur/heme enzyme. J. Biol. Chem. 276, 21381-21386. DOI: 10.1074/jbc.M101679200
Kniemeyer O. & Heider J. (2001) (S)-1-Phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism. Arch. Microbiol. 176, 129-135. DOI: 10.1007/s002030100303
Leutwein C. & Heider J. (2001) Succinyl-CoA: (R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria. J. Bacteriol. 183, 4288-4295. DOI: 10.1128/JB.183.14.4288-4295.2001
2000
Leuthner B. & Heider J. (2000) Anaerobic toluene catabolism of Thauera aromatica: a toluene-induced operon codes for the enzymes of b-oxidation of the intermediate benzylsuccinate. J. Bacteriol. 182, 272-277. DOI: 10.1128/jb.182.2.272-277.2000
1999
Leutwein C. & Heider J. (1999) Anaerobic toluene catabolic pathway in denitrifying Thauera aromatica: activation and b-oxidation of the first intermediate, (R)-(+)-benzylsuccinate. Microbiol. 145, 3265- 3271. DOI: 10.1099/0021287-145-11-3265
Zengler K., Heider J., Rosselló-Mora R. & Widdel F. (1999) Phototrophic utilisation of toluene under anoxic conditions by a new strain of Blastochloris sulfoviridis. Arch. Microbiol. 172, 204-212. DOI: 10.1007/s002030050761
1998
Heider J., Boll M., Breese K., Breinig S., Ebenau-Jehle C., Feil U., Gad’on N., Laempe D., Leuthner B., Mohamed M., Schneider S., Burchhardt G. & Fuchs G. (1998) Differential induction of enzymes involved in anaerobic metabolism of aromatic compounds in the denitrifying bacterium Thauera aromatica. Arch. Microbiol. 170, 120-131. DOI: 10.1007/s002030050623
Leuthner B. & Heider J. (1998) A two-component system involved in regulation of anaerobic toluene metabolism in Thauera aromatica. FEMS Microbiol. Lett. 166, 35-41. DOI: 10.1111/j.1574-6968.1998.tb13180.x
Leuthner B., Leutwein C., Schulz H., Hörth P., Haehnel H., Schiltz E., Schägger H. & Heider J. (1998) Biochemical and genetic characterisation of benzylsuccinate synthase from Thauera aromatica: a new glycyl-radical enzyme catalysing the first step in anaerobic toluene metabolism. Molec. Microbiol. 28, 615-628. DOI: 10.1046/j.1365-2958.1998.00826.x
Rabus R. & Heider J. (1998) Initial reactions of anaerobic metabolism of alkylbenzenes in denitrifying and sulfate-reducing bacteria. Arch. Microbiol. 170, 377-384. DOI: org/10.1007/s002030050656
1997
Müller S., Heider J. & Böck A. (1997) The path of unspecific incorporation of selenium in Escherichia coli. Arch. Microbiol. 168, 421-427. DOI: 10.1007/s002030050517
1996
Biegert T., Fuchs G. & Heider J. (1996) Evidence that anaerobic oxidation of toluene in the denitrifying bacterium Thauera aromatica is initiated by formation of benzylsuccinate from toluene and fumarate, Eur. J. Biochem. 238, 661-668. DOI: 10.1111/j.1432-1033.1996.0661w.x
Heider J., Mai X. & Adams M. W. W. (1996) Characterisation of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A dependent enzyme involved in peptide fermentation by hyperthermophilic archaea. J. Bacteriol. 178, 780-787. DOI: 10.1128/jb.178.3.780-787.1996
Hüttenhofer A., Heider J. & Böck A. (1996) Interaction of the Escherichia coli fdhF hairpin promoting selenocysteine incorporation with the ribosome. Nucl. Acids Res. 24, 3903-3910. DOI: 10.1093/nar/24.20.3903
1995
Heider J., Ma K. & Adams M. W. W. (1995) Purification, characterisation and metabolic function of tungsten-containing aldehyde ferredoxin oxidoreductase from the hyperthermophilic archaeon Thermococcus strain ES-1. J. Bacteriol. 177, 4757-4764. DOI: 10.1128/jb.177.16.4757-4764.1995
Ma K., Loessner H., Heider J., Johnson M. K. & Adams M. W. W. (1995) Effects of elemental sulfur on the metabolism of the deep-sea hyperthermophilic archaeon Thermococcus strain ES-1: characterisation of a sulfur-regulated, non-heme iron alcohol dehydrogenase. J. Bacteriol. 177, 4748-4756. DOI: 10.1128/jb.177.16.4748-4756.1995
1994
Tormay P., Wilting R., Heider J. & Böck A. (1994) Genes coding for the selenocysteine-inserting tRNA species from Desulfomicrobium baculatum and Clostridium thermoaceticum: structural and evolutionary implications. J. Bacteriol. 176, 1268-1274. DOI: 10.1128jb.176.5.1268-1274.1994
1993
Baron C., Heider J. & Böck A. (1993) Interaction of translation factor SELB with the formate dehydrogenase H selenopolypeptide mRNA. Proc. Natl. Acad. Sci. USA 90, 4181-4185. DOI: 10.1073/pnas.90.9.4181
1992
Heider J., Baron C. & Böck A. (1992) Coding from a distance: dissection of the mRNA determinants required for the incorporation of selenocysteine into protein. EMBO J. 11, 3759-3766. PMCID: doi.org/10.1002/j.1460-2075.1992.tb05461.x
Heider J. & Böck A. (1992) Targeted insertion of selenocysteine into the a-subunit of formate dehydrogenase from Methanobacterium formicicum. J. Bacteriol. 174, 659-663. DOI: 10.1128/jb.174.3.659-663.1992
1991
Berg B. L., Li J., Heider J. & Stewart V. (1991) Nitrate-inducible formate dehydrogenase in Escherichia coli K-12: I. Nucleotide sequence of the fdnGHI operon and evidence that opal (UGA) encodes selenocysteine. J. Biol. Chem. 266, 22380-22385. DOI: org/10.1016/S0021-9258(18)54583-X
Heider J., Forchhammer K., Sawers G. & Böck A. (1991) Interspecies compatibility of selenoprotein biosynthesis in Enterobacteriaceae. Arch. Microbiol. 155, 221-228. DOI: 10.1128/jb.173.16.4983-4993.1991
Sawers G., Heider J., Zehelein E. & Böck A. (1991) Expression and operon structure of the sel genes of Escherichia coli and identification of a third selenium-containing formate dehydrogenase isoenzyme. J. Bacteriol. 173, 4983-4993. DOI: 10.1128/jb.173.16.4983-4993.1991
1990
Baron C., Heider J. & Böck A. (1990) Mutagenesis of selC, the gene for the selenocysteine-inserting tRNA-species in E. coli: effects on in vivo function. Nucl. Acids Res. 18, 6761-6766. DOI: 10.1093/nar/18.23.6761
Zinoni F., Heider J. & Böck A. (1990) Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine. Proc. Natl. Acad. Sci. USA 87, 4660-4664. DOI: 10.1073/pnas.87.12.4660
1989
Heider J., Leinfelder W. & Böck A. (1989) Occurrence and functional compatibility of a tRNA species which inserts selenocysteine into protein. Nucl. Acids Res. 17, 2529-2540. DOI: 10.1093/nar/17.7.2529
Reviews
2020
Seelmann C. S., Willistein M., Heider, J. & Boll M. (2020) Tungstoenzymes: occurrence, catalytic diversity and cofactor synthesis. Inorganics 8, 44. DOI: 10.3390/inorganics8080044
2018
Czech L., Hermann L., Stöveken N., Richter A. A., Höppner A., Smits S. H. J., Heider J., Bremer E. (2018) Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry and structural analysis. Genes 9, E177. DOI: 10.3390/genes9040177
Boll M., Estelmann S. & Heider J. (2018) Catabolic pathways and enzymes involved in the anaerobic degradation of monocyclic aromatic compounds. In: Boll M. (ed) Anaerobic Utilization of Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer, Cham. DOI: 10.1007/978-3-319-33598-8_6-1
Boll M., Estelmann S. & Heider J. (2018) Anaerobic Degradation of Hydrocarbons: Mechanisms of Hydrocarbon Activation in the Absence of Oxygen. In: Boll M. (ed) Anaerobic Utilization of Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer, Cham. DOI: 10.1007/978-3-319-33598-8_2-1
2016
Rabus R., Boll M., Heider J., Meckenstock R. U., Buckel W., Einsle O., Ermler U., Golding B. T., Gunsalus R., Kroneck P. M. H., Krüger M., Lueders T., Martins B. M., Musat F., Richnow H. H., Schink B., Seifert J., Szaleniec M., Treude T., Ullmann G. M., Vogt C., von Bergen M. & Wilkes H. (2016) Anaerobic Microbial Degradation of Hydrocarbons - From Enzymatic Reactions to the Environment. J. Mol. Microbiol. Biotechnol. 26, 5-28. DOi: 10.1159/000443997
Heider J., Szaleniec M., Martins B. M., Seyhan D., Buckel W. & Golding B. T. (2016) Structure and function of benzylsuccinate synthase and related fumarate-adding glycyl radical enzymes. J. Mol. Microbiol. Biotechnol. 26, 29-44. DOI: 10.1159/000441656
Heider J., Szaleniec M., Sünwoldt K. & Boll M. (2016) Ethylbenzene dehydrogenase and related molybdenum enzymes involved in oxygen-independent alkyl chain hydroxylation. J. Mol. Microbiol. Biotechnol. 26, 45-62. DOI: 10.1159/000441357
Heider J., Schühle K., Frey J. & Schink B. & (2016) Activation of acetone and other ketones in anaerobic bacteria. J. Mol. Microbiol. Biotechnol. 26, 152-164. DOI: 10.1159/000441500
2015
Heider J. & Fuchs G. (2015) Thauera. In: Bergey's Manual of Systematics of Archaea and Bacteria (W. B. Whitman ed.), John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: 10.1002/9781118960608.gbm01004
2013
Heider J. & Schühle K. (2013) Anaerobic biodegradation of hydrocarbons including methane. In: The Prokaryotes: Prokaryotic Physiology and Biochemistry., 4th ed. (Rosenberg E., DeLong E.F., Thompson F., Lory S., Stackebrandt E. eds), Chapter 80, pp. 601-630, Springer-Verlag, Heidelberg. DOI: 10.1007/978-3-642-30141-4_80
2011
Fuchs G., Boll M. & Heider J. (2011) Microbial degradation of aromatic compounds – from one strategy to four. Nature Rev. Microbiol. 9, 803-816. DOI: 10.1038/nrmicro2652
2009
Boll M. & Heider J. (2009) Anaerobic Degradation of Hydrocarbons: Mechanisms of C-H-bond activation in the absence of oxygen. In: Handbook of Hydrocarbon and Lipid Microbiology (K. N. Timmis ed.), pp. 1011-1024, Springer-Verlag, Heidelberg. DOI: 10.1007/978-3-540-77587-4_71
2008
Heider J. (2008) Bakterieller Kohlenwasserstoff-Abbau—es geht auch ohne Sauerstoff. Biospektrum 14, 28-31
Heider J. & Rabus R. (2008) Genomic insights in the anaerobic biodegradation of organic pollutants. In: Microbial biodegradation: Genomics and molecular biology (E. Diaz ed.), pp. 25-54, Caister academic press, Norfolk, UK
2007
Heider J. (2007) Adding handles to unhandy substrates: anaerobic hydrocarbon activation mechanisms. Curr. Opin. Chem. Biol. 11, 188-194. DOI: 10.1016/j.cbpa.2007.02.027
2005
Selmer T., Pierik A. J., Heider J. (2005) New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria. Biol. Chem. 386, 981-988. DOI: 10.1515/BC.2005.114
Heider J. & Fuchs G. (2005) Genus Thauera. In: Bergey’s Manual of Systematic Bacteriology (2nd ed); Vol. 2, part C (G. Garitty, ed.), pp. 907-913, Springer Verlag, Berlin
2002
Boll M., Fuchs G. & Heider J. (2002) Anaerobic oxidation of aromatic compounds and hydrocarbons. Curr. Opin. Chem. Biol. 6, 604-611. DOI: 10.1016/s1367-5931(02)00375-7
2001
Heider J. (2001) A new family of CoA-transferases. FEBS Lett. 509, 345-349. DOI: 10.1016/s0014-5793(01)03178-7
2000
Heider J. (2000) Toluol-Stoffwechsel ohne Sauerstoff: eine (Glycyl-)radikale Lösung. Biospektrum 6, 280-281
1998
Heider J., Spormann, A. M., Beller H. R. & Widdel, F. (1998) Anaerobic bacterial metabolism of hydrocarbons. FEMS Microbiol. Rev. 22, 459-473. DOI: 10.1111/j.1574-6976.1998.tb00381.x
1997
Heider J. & Fuchs G. (1997) Anaerobic metabolism of aromatic compounds, Eur. J. Biochem. 243, 577-596. DOI: 10.1111/j.1432-1033.1997.00577.x
Heider J. & Fuchs G. (1997) Microbial anaerobic aromatic metabolism, Anaerobe 3, 1-22. DOI: 10.1006/anae.1997.0073
1993
Heider J. & Böck A. (1993) Selenium metabolism in micro-organisms. Adv. Microb. Physiol. 35, 71-109. DOI: 10.1016/s0065-2911(08)60097-1
1991
Böck A., Forchhammer K., Heider J. & Baron C. (1991) Selenoprotein synthesis: an expansion of the genetic code. Trends Biochem. Sci. 16, 463-467. DOI: 10.1016/0968-0004(91)90180-4
Böck A., Forchhammer K., Heider J., Leinfelder W., Sawers G., Veprek B. & Zinoni F (1991) Selenocysteine: the 21st amino acid. Molec. Microbiol. 5, 515-520. DOI: 10.1111/j.1365-2958.1991.tb00722.x
1990
Böck A., Baron C., Forchhammer K., Heider J., Leinfelder W., Sawers G., Veprek B., Zehelein E. & Zinoni F. (1990) From nonsense to sense: UGA encodes selenocysteine in formate dehydrogenase and other selenoproteins. In: 41. Colloquium Mosbach: The molecular basis of bacterial metabolism (G. Hauska & R. Thauer eds.), pp. 61-68, Springer Verlag, Berlin
Patente
Luo S., Erb T. & Heider J. (2023) ATP production from electricity with a new-to-nature electrobiological module
Winiarska A., Szaleniec M., Heider J., Hege D., Arndt F., Wojtkiewicz A. (2022) A method of enzymatic reduction of the oxidized nicotinamide adenine dinucleotide and carboxylic acids. EP Patent Application Pub. No. EP22164459; EP4092126A1
Winiarska A., Heider J., Szaleniec M., Hege D., Arndt F. (2021) Sposób enzymatycznej redukcji formy utlenionej dinukleotydu nikotynowo-adeninowego (Method of enzymatic reduction of the oxidized form of nicotine adenine dinucleotide). Polish Patent Application Pub. No. P.437449; PL437449A1
Winiarska A., Heider J., Szaleniec M., Hege D., Arndt F. (2021) Sposób otrzymywania aldehydów poprzez enzymatyczną redukcję kwasów karboksylowych (Method of obtaining aldehydes by enzymatic reduction of carboxylic acids). Polish Patent Application Pub. No. P.437445; PL437445A1
Stürmer R., Schneider N., Boy M., Achatz B., Rabus R., Heider J, (2011) Method for preparing optically active hydroxy acid esters. Application No.: PCT/EP2010/060458, Pub No WO002011009849A2
Breuer M., Rabus R., Heider J. (2010) Method for production of optically active alcohols using an Azoarcus sp. EbN1 dehydrogenase. Intl. Appl. No. PCT/EP2008/057522, Pub. Nos. CA000002691799A1, CN000101796192A, EP000002171074A1, MX002009014055A, US020100143991A1, WO002008155302A1
Candussio A., Amann M., Wich G., Heider J. (2008) Method for effecting the anaerobic biological decomposition of organosiloxanes. Appl Nr EP20050715924, Pub. Nos. EP000001749100B1, EP000001749100A1, WO002005087939A1
Fischer M., Heider J. (2007) Verfahren zum anaeroben Abbau von organo-funktionalisierten Silicium-Verbindungen, Silanen und Siloxanen durch Bakterien. Appl No 102006007292, Pub No DE102006007292A1
Fischer M., Heider J. (2007) Verfahren zum anaeroben Abbau von Organosilicium-Verbindungen durch Bakterien der Gattung Paracoccus. Appl No 2007051116, Pub No WO002007093523A1
Candussio A., Amann M., Wich G., Heider J. (2005) Anaerober Abbau von Polyorganosiloxanen und Organosilanen. Appl No 102004011993, Pub No DE102004011993A1