Hauptinhalt

Publikationen

Originalveröffentlichungen 
 

2024

Gemmecker Y., Winiarska A., Hege D., Kahnt J., Seubert A., Szaleniec M., Heider J. (2024) A pH-dependent shift of redox cofactor specificity in a benzyl alcohol dehydrogenase of Aromatoleum aromaticum EbN1. Appl. Microbiol. Biotechnol. submitted.

Pöhl S., Giacomelli G., Meyer F., Kleeberg V., Cohen E. J., Biboy J., Rosum J., Glatter T., Vollmer W., Beeby M., van Teeseling M. C. F., Heider J., Brankamp M. & Thanbichler M. (2024) An outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in Rhodospirillum rubrum. Nature Commun. submitted.

Szaleniec M., Oleksy G., Sekuła A., Aleksic I., Pietras R., Sarewicz M., Krämer K., Pierik A. J., Heider J. (2024) Modeling the initiation phase of the catalytic cycle in the glycyl-radical enzyme benzylsuccinate synthase. Journal Phys. Chem. B 128, 24, 5823 - 5839. Doi:10.1021/acs.jpcb.4c01237

Andrys-Olek J., Kluza A., Tataruch M., Heider J., Korecki J., Borowski T.M. (2024) Bacteria at work – Experimental and theoretical studies reveal the catalytic mechanism of ectoine synthase. Chemistry Europe Journal. Volume 30, e202304163. DOI:10.1002/chem.202304163

Mock J., Schühle K., Linne U., Mock M. & Heider J. (2024) A synthetic pathway for the production of benzylsuccinate in Escherichia coli. MDPI Molecules  29(2), 415. DOI:10.3390/29020415

2023

Luo S. Adam D.  Giaveri S., Barthel S., Cestellos-Blanco S., Hege D., Paczia N., Castañeda-Losada L., Klose M., Arndt F., Heider J. & Erb T. J. (2023) ATP production from electricity with a new-to-nature electrobiological module. Joule 7, 1745-1758. DOI:10.1016/j.joule.2023.07.012

Winiarska A., Ramírez-Amador F., Hege D., Gemmecker Y., Prinz S., Hochberg G., Heider J., Szaleniec M., Schuller J. M. (2023) A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire. Science Adv  9, eadg6689. DOI: 10.1101/2023.01.23.525143

Kalimuthu P., Hege D., Winiarska A., Gemmecker Y., Szaleniec M., Heider J., Bernhardt P. V. (2023) Electrocatalytic aldehyde oxidation by a tungsten dependent aldehyde oxidoreductase from Aromatoleum aromaticum. Chemistry European JournalDOI:10.1002/202203072

Andrys-Olek J., Heider J., Borowski T. (2023) Molecular Dynamics simulations for the Michaelis complex of Ectoine Synthase (EctC). Catalysts 13, 124. DOI: 10.3390/catal13010124

Shalygin M. G., Kozlova A.A., Heider J., Sapegin D.A., Netrusov A.A. & Teplyakov (2023) Polymeric membranes for vapor-base concentrating volatile organic products from biomass processing. Membranes Membr Technol 5, 65-80. DOI://10.1134/S2517751623010055 

2022

Lo H.-Y., Matinéz-Lavanchy P., Goris T., Heider J., Boll M., Kaster A.-K. & Müller J. A. (2022) IncP-type plasmids carrying genes for antibiotic resistance or for aromatic compound degradation are prevalent in sequenced Aromatoleum and Thauera strains. Environ. Microbiol. 24, 6411-6425. DOI: 10.1111/1462-2920.16262

Chistyakova P. A., Chistyakov A. V., Nikolaev S. A., Bagdatov R. A., Tsodikov M. V., Heider J. & Netrusov A. I. (2022) Conversion of ethanol and fusel oils over Au-M/MFI/Al2O3 calalysts. Petrol. Chem. 62, 1107-1125. DOI: 10.1134/S0965544122090018

Steinhilper R., Höff G., Heider J., Murphy B. J. (2022) Structure of the membrane-bound formate hydrogen lyase complex from Escherichia coli. Nature Comm. 13, 5395. DOI: 10.1101/2022.03.21.484881

Winiarska A., Hege D., Gemmecker Y., Kryściak-Czerwenka J., Seubert A., Heider J., Szaleniec M. (2022) A tungsten enzyme using hydrogen as an electron donor to reduce carboxylic acids and NAD+. ACS Catalysis 12, 8707-8717. DOI: 10.1021/acscatal.2c02147

Weidenweber S., Schühle K., Lippert M.-L., Mock J., Seubert A., Demmer U., Ermler U. & Heider J. (2022) Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyses the final step of anaerobic toluene metabolism. FEBS J. 289, 5599-5616. DOI: 10.1111/febs.16443

von Horsten S., Lippert M.-L., Geisselbrecht Y., Schühle K., Schall I., Essen L.-O., Heider J. (2022) Inactive pseudoenzyme subunits in heterotetrameric BbsCD, a novel short-chain alcohol dehydrogenase involved in anaerobic toluene degradation. FEBS J. 289, 1023-1042. DOI: 10.1111/febs.16216

Hagel C., Blaum B., Friedrich T. & Heider J. (2022) Characterisation of the redox centers of ethylbenzene dehydrogenase. J. Biol. Inorg. Chem. 27, 143-154. DOI: 10.1007/s00775-021-01917-0

2021

Andrys J., Heider J., Borowski T. (2021) Comparison of different approaches to derive classical bonded force-field parameters for a transition metal cofactor. A case study for non-heme iron site of ectoine synthase. Theor. Chem. Acc. 140, 115. DOI: 10.1007/s00214-021-02796-z

Schühle K., Saft M., Vögeli B., Erb T. J., Heider J. (2021) Benzylmalonyl-CoA dehydrogenase, an enzyme involved in bacterial auxin degradation. Arch Microbiol. accepted. DOI: 10.21203/rsa.3.5s-466161/v1

Salii I., Szaleniec M., Alhaj Zein A., Seyhan D., Sekula A., Schühle K., Kaplieva-Dudek I., Linne U., Meckenstock R. U. & Heider J. (2021) Determinants for substrate recognition in the glycyl radical enzyme benzylsuccinate synthase revealed by targeted mutagenesis. ACS Catal.11, 3361-3370. DOI: 10.1021/acscatal.0c04954

2020

Borowiecki P., Teltycka N., Tataruch M., Żądło-Dobrowolska A., Reiter T., Schühle K., Heider J., Szaleniec M., Kroutil W. (2020) Biocatalytic asymmetric reduction of γ‐keto esters to access optically active γ‐aryl‐γ‐butyrolactones. Adv. Synth. Catal. 362, 2012-2029. DOI: 10.1002/adsc.201901483

2019

Vogt M. S., Kölzer S., Schühle K., Peschke P., Schall I., Chowdhury N. P., Buckel W., Kleinsorge D., Essen L.-O., Heider J. (2019) Diversity of electron transferring flavoproteins: structure and function of a paralogue involved in anaerobic toluene metabolism. J. Bacteriol. 201, 00326-19. DOI: 10.1128/JB.00326-19

Schmitt G., Saft M., Arndt F., Kahnt J., Heider J. (2019) Two different quinohemoprotein amine dehydrogenases initiate anaerobic degradation of aromatic amines in Aromatoleum aromaticum EbN1. J. Bacteriol. 201, e00281-19. DOI: 10.1128/JB.00281-19

Arndt F., Schmitt G., Winiarska A., Saf M.t, Seubert A., Kahnt J., Heider J. (2019) Characterisation of an aldehyde oxidoreductase from the mesophilic bacterium Aromatoleum aromaticum, a member of a new subfamily of tungsten-containing enzymes. Front. Microbiol. 10, 71. DOI: 10.3389/fmicb.2019.00071

Czech L., Höppner A., Kobus S., Seubert A., Riclea R., Dickschat J. S., Heider J., Smits S. H. J. & Bremer E. (2019) Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis. Nature Sci. Rep. 9, 364. DOI: 10.1038/s41598-018-36247-w

Özcan A., Pausch P., Linden A., Wulf A., Schühle K., Heider J., Urlaub H., Heimerl T., Bange G, and Randau L. (2019) Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiol. 4, 89-96. DOI: 10.1038/s41564-018-0274-8

2018

León M. J., Hoffmann T., Sánchez-Porro C., Heider J., Ventosa A. & Bremer E. (2018) Compatible solute synthesis and import by the moderate halophile Spiribacter salinus: physiology and genomics. Front. Microbiol. 9, 108. DOI: 10.3389/fmicb.2018.00108

2017

Schulz A., Hermann L., Freibert S.-A., Bönig T., Hoffmann T., Ricela R., Dickschat J. S., Heider J. Bremer E. (2017) Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues. Environ. Microbiol. 19, 4599-4619. DOI: 10.1111/1462-2920.13924

Warkentin E., Weidenweber S., Schühle K., Demmer U., Heider J. & Ermler U. (2017) A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins 85, 2017-2023. DOI: 10.1002/prot.25355

Schmitt G., Arndt F., Kahnt J., Heider J. (2017) Adaptations to a loss-of-function mutation in the betaproteobacterium Aromatoleum aromaticum: recruitment of alternative enzymes for anaerobic phenylalanine degradation. J. Bacteriol. 199, e00383-17. DOI: 10.1128/JB.00383-17

Schulz A.,  Stöveken N., Binzen I. M., Hoffmann T., Heider J. Bremer E. (2017) Feeding on compatible solutes: a substrate-induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR. Environ. Microbiol. 19, 926-946. DOI: 10.1111/1462-2920.13414

 Weidenweber S., Schühle K., Demmer U., Warkentin E., Ermler U. & Heider J. (2017) Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Nature Sci. Rep. 7, 39674. DOI: 10.1038/srep39674

2016

Schühle K., Nies J. & Heider J. (2016) An indoleactate-CoA ligase and a phenylsuccinate CoA-transferase involved in anaerobic indoleacteate metabolism. Environ. Microbiol. 18, 3120-3132. DOI: 10.1111/1462-2920.13347

Seyhan D., Friedrich P., Szaleniec M., Hilberg M., Golding B. T., Buckel W. & Heider J. (2016) Elucidating the Stereochemistry of Enzymatic Benzylsuccinate Synthesis with Chirally Labeled Toluene. Angew. Chemie Int. Ed. 55, 11664-11667. DOI: 10.1002/anie.201605197

Seyhan D., Friedrich P., Szaleniec M., Hilberg M., Golding B. T., Buckel W. & Heider J. (2016) Stereochemischer Verlauf der enzymatischen Synthese von Benzylsuccinat mit chiral markiertem Toluol. Angew. Chemie 128, 11832-11835. DOI: 10.1002/ange.201605197

Szaleniec  M. & Heider J. (2016) Modeling of the reaction mechanism of enzymatic radical C-C coupling by benzylsuccinate synthase. Int. J. Mol. Sci. 17,514. DOI: 10.3390/ijms17040514

Widderich N., Kobus S., Hoeppner A., Riclea R., Seubert A., Dickschat J., Heider J., Smits S. H. J. & Bremer E. (2016) Biochemistry and crystal structure of the ectoine synthase: a metal-containing member of the cupin superfamily. PLoS One, 11, e0151285. eCollection 2016. DOI: 10.1371/journal.pone.0151285

Muhr E., Leicht O., González Sierra S., Thanbichler M. & Heider J. (2016) A fluorescent bioreporter for acetophenone and 1-phenylethanol derived from a specifically induced catabolic operon. Front. Microbiol. 6, 1561. DOI: 10.3389/fmicb.2015.01561

Widderich N., Czech L., Elling F. J., Könneke M., Stöveken N., Pittelkow M., Riclea R., Dickschat J., Heider J. & Bremer E. (2016) Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus. Environ. Microbiol. 18, 1227-1248. DOI: 10.1111/1462-2920.13156

2015

Dudzik A., Snoch W., Borowiecki P., Opalinska-Piskorz J., Witko M., Heider J., Szaleniec M. (2015) Asymmetric reduction of ketones and β-keto esters by (S)-1-phenylethanol dehydrogenase from denitrifying bacterium Aromatoleum aromaticum. Appl. Microbiol. Biotechnol. 99, 5055-5069. DOI: 10.1007/s00253-014-6309-z

Muhr E., Schühle K., Clermont L., Sünwoldt K., Kleinsorge D., Seyhan D., Kahnt J., Schall I., Cordero P. R., Schmitt G. & Heider J. (2015) Enzymes of anaerobic ethylbenzene and p-ethylphenol catabolism in Aromatoleum aromaticum: differentiation and differential induction. Arch. Microbiol. 197, 1051-1062. DOI: 10.1111/1462-2920.13414

Kalimuthu P., Heider J., Knack D. & Bernhardt P. V. (2015) Electrocatalytic hydrocarbon hydroxylation by ethylbenzene dehydrogenase from Aromatoleum aromaticum. J. Phys. Chem. B 119, 3456-3463. DOI: 10.1012/jp512562k

2014

Debnar-Daumler C., Seubert A., Schmitt G. & Heider J. (2014) Simultaneous involvement of a tungsten-containing aldehyde:ferredoxin oxidoreductase and a phenylacetaldehyde dehydrogenase in anaerobic phenylalanine metabolism. J. Bacteriol. 196, 483-492. DOI: 10.1128/JB.00980-13

Szaleniec M., Dudzik A., Kozik B.,  Borowski T., Heider J. & Witko M. (2014) Mechanistic basis for the enantioselectivity of anaerobic hydroxylation of alkylaromatic compounds by  ethylbenzene dehydrogenase. J. Inorgan. Biochem. 139, 9-20. DOI: 10.1016/j.jinorgbio.2014.05.006

Tataruch M., Bryjak J., Nowak P., Knack D., Czerniak A., Liesiene J., Heider J. & Szaleniec M. (2014) Suitability of the hydrocarbon-hydroxylating molybdenum-enzyme ethylbenzene dehydrogenase for industrial chiral alcohol production. J. Biotechnol. 192, 400-409. DOI: 10.1016/j.jbiotec.2014.06.021

Widderich N., Höppner A., Pittelkow M., Heider J., Smits S. H. J. & Bremer E. (2014) Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms. PLOS One 9, e93809. DOI: 10.1371/journal.pone.0093809

2013

Dudzik A., Kozik B., Tataruch M., Wójcik A., Knack D., Borowski T., Heider J., Witko M. & Szaleniec M. (2013) The reaction mechanism of chiral hydroxylation of p-OH and p-NH2 substituted compounds by ethylbenzene dehydrogenase. Can J. Chem. 91, 775-786. DOI: 10.1139/cjc-2012-0504

Knack D. H, Marshall J. L., Harlow G. P., Dudzik A., Szaleniec M., Liu S.-Y. & Heider J. (2013) BN/CC-isosterische Verbindungen als Enzyminhibitoren: Hemmung der Hydroxylierung von Ethylbenzol durch N - und B -Ethyl-1,2-azaborin als nichtkonvertierbare Substratanaloga.,Angew. Chemie 125, 2660 –2662. DOI: org/10.1002/ange.201208351

Knack D. H, Marshall J. L., Harlow G. P., Dudzik A., Szaleniec M., Liu S.-Y. & Heider J. (2013) BN/CC isosteric compounds as enzyme inhibitors: N- and B-ethyl-1,2-azaborine inhibit ethylbenzene hydroxylation as nonconvertible substrate analogs. Angew. Chemie Int. Ed. 52, 2599-2601. DOI: 10.1002/anie.201208351

Kümmel S., Kuntze K., Vogt C., Boll M., Heider J. & Richnow H. H. (2013) Evidence for benzylsuccinate synthase subtypes by stable isotope tools. J. Bacteriol. 195, 4660-4667. DOI: 10.1128/JB.00477-13

2012

Ebenau-Jehle C., Thomas M., Scharf G., Kockelkorn D., Knapp B., Schühle K., Heider J. & Fuchs G. (2012) Anaerobic Metabolism of Indoleacetate. J. Bacteriol. 194, 2894-2903. DOI: 10.1128/JB.00250-12

Hilberg M., Pierik A. J., Bill E., Friedrich T., Lippert M.-L. & Heider J. (2012) Identification of FeS-clusters in the glycyl radical enzyme benzylsuccinate synthase via EPR and Mössbauer spectroscopy. J. Biol. Inorg. Chem. 17, 49-56. DOI: 10.1007/s0075-011-0828-1

Knack D., Hagel C., Szaleniec M., Dudzik A., Salwinski A. & Heider J. (2012) Substrate and inhibitor spectrum of ethylbenzene dehydrogenase: implications on application potential and enzyme mechanism. Appl. Environ. Microbiol. 78, 6475-6482. DOI: 10.1128/AEM.01551-12

Schühle K. & Heider J. (2012) Acetone and butanone metabolism of the denitrifying bacterium “Aromatoleum aromaticum” demonstrates novel biochemical properties of an ATP-dependent aliphatic ketone carboxylase. J. Bacteriol. 194, 131-141. DOI: 10.1128/JB.05898-11

Szaleniec M., Salwinski A., Borowski T., Heider J. & Witko M. (2012) Quantum chemical modeling studies of ethylbenzene dehydrogenase activity. Intl. J. Quant. Chem. 112, 1990-1999. DOI: org/10.1002/qua.23143

2011

Rabus R., Jarling R., Lahme S., Kühner S., Heider J., Widdel F. & Wilkes H. (2011) Co-metabolic conversion of toluene in anaerobic n-alkane-degrading bacteria. Environ. Microbiol. 13, 2576-2586. DOI: 10.1111/j.1462-2920.2011.02529.x

Stöveken N., Pittelkow M., Sinner T., Jensen R. A., Heider J. & Bremer E. (2011) A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501. J. Bacteriol. 193, 4456-4468. DOI: 10.1128JB.00345-11

2010

Jobst B., Schühle K., Linne U. & Heider J. (2010) ATP-dependent carboxylation of acetophenone by a novel type of carboxylase. J. Bacteriol. 192, 1387-1394. DOI: 10.1128/JB.01423-09

Müller F. D., Treuner-Lange A., Heider J., Huntley S. M., Higgs P. I. (2010) Global transcriptome analysis of spore formation in Myxococcus xanthus reveals a locus necessary for cell differentiation. BMC Genomics 11, 264. DOI: 10.1186/1471-2164-11-264

Szaleniec M., Borowski T., Schühle K., Witko M. & Heider  J. (2010) Ab initio modelling of ethylbenzene dehydrogenase reaction mechanism. J. Amer. Chem. Soc. 132, 6014-6024. DOI: 10.1021/ja907208k

2008

Grundmann O., Behrends A., Rabus R., Amann J., Halder T., Heider J. & Widdel F. (2008) Genes encoding a tentative enzyme for anaerobic activation of n-alkanes in the denitrifying bacterium, strain HxN1. Environ. Microbiol. 10, 376-385. DOI: 10.1111/j.1462-2920.2007.01458.x

Szaleniec M., Witko M & Heider J. (2008) Quantum chemical modelling of C-H cleavage mechanism in oxidation of ethylbenzene and its derivates by ethylbenzene dehydrogenase. J. Molec. Catal. A, 286, 128-136. DOI: org./10.1016/j.molcata.2008.02.016

2007

Szaleniec M., Hagel C., Menke M., Nowak P., Witko M. & Heider J. (2007) Kinetics and mechanism of oxygen-independent hydrocarbon-hydroxylation by ethylbenzene dehydrogenase. Biochemistry 46, 7637-7646. DOI: 10.1021/bi700633c

2006

Höffken H. W., Duong M., Friedrich T., Breuer M., Hauer B., Reinhardt R., Rabus R., Heider J. (2006) Crystal structure and enzyme kinetics of the (S)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain EbN1. Biochemistry, 45, 82-93. DOI: 10.1021/bi051596b

Kloer D. P., Hagel C., Heider J. & Schulz, G. E. (2006) Crystal Structure of Ethylbenzene dehydrogenase from Aromatoleum aromaticum. Structure 14, 1377-1388. DOI: 10.1016j.str.2006.07.001

2005

Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F. & Reinhard R. (2005) The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1. Arch. Microbiol. 183, 27-36. DOI: 10.1007/s00203-004-0742-9

2004

Kube M., Heider J., Amann J., Hufnagel P., Kühner S., Beck A., Reinhardt R. & Rabus R. (2004) Genes involved in the anaerobic degradation of toluene in a denitrifying bacterium, strain EbN1. Arch. Microbiol. 181, 182-194. DOI: 10.1007/s00203-003-0627-3

Verfürth K., Pierik A. J., Leutwein C., Zorn S. & Heider J. (2004) Substrate specificities and electron paramagnetic resonance properties of benzylsuccinate synthases in anaerobic toluene- and m-xylene-metabolism. Arch. Microbiol. 181, 155-162. DOI: 10.1007/s00203-003-0642-4

2003

Duboc-Toia C., Hassan A. K., Mulliez E., Ollagnier-de Choudens S., Fontecave M., Leutwein C. & Heider J. (2003) Very high field EPR studies of glycyl radical enzymes. J. Amer. Chem. Soc. 125, 38-39. DOI: 10.1021/ja026690j

Szaleniec M., Jobst B. & Heider J. (2003) Ethylbenzene dehydrogenase: oxidation of hydrocarbons without oxygen. Ann. Pol. Chem.Soc. 2003, 240-245. 

2002

Hermuth K., Leuthner B. & Heider J. (2002) Operon structure and expression of the genes for benzylsuccinate synthase in Thauera aromatica strain K172. Arch. Microbiol. 177, 132-138. DOI: 10.1007/s00203-001-0375-1

Leutwein C. & Heider J. (2002) (R)-Benzylsuccinyl-CoA dehydrogenase from Thauera aromatica: a new acyl-CoA dehydrogenase involved in anaerobic toluene catabolism. Arch. Microbiol. 178, 517-524. DOI: 10.1007/s00203-002-0484-5

Mohamed M. E., Ismail W., Heider J. & Fuchs G (2002) Aerobic metabolism of phenylacetic acids in Azoarcus evansii. Arch. Microbiol. 178, 180-192. DOI: 10.1007/s00203-002-0438-y

2001

Kniemeyer O. & Heider J. (2001) Ethylbenzene dehydrogenase, a novel hydrocarbon-oxidising molybdenum/iron-sulfur/heme enzyme. J. Biol. Chem. 276, 21381-21386. DOI: 10.1074/jbc.M101679200  

Kniemeyer O. & Heider J. (2001) (S)-1-Phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism. Arch. Microbiol. 176, 129-135. DOI: 10.1007/s002030100303

Leutwein C. & Heider J. (2001) Succinyl-CoA: (R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria. J. Bacteriol. 183, 4288-4295. DOI: 10.1128/JB.183.14.4288-4295.2001

2000

Leuthner B. & Heider J. (2000) Anaerobic toluene catabolism of Thauera aromatica: a toluene-induced operon codes for the enzymes of b-oxidation of the intermediate benzylsuccinate. J. Bacteriol. 182, 272-277. DOI: 10.1128/jb.182.2.272-277.2000

1999

Leutwein C. & Heider J. (1999) Anaerobic toluene catabolic pathway in denitrifying Thauera aromatica: activation and b-oxidation of the first intermediate, (R)-(+)-benzylsuccinate. Microbiol. 145, 3265- 3271. DOI: 10.1099/0021287-145-11-3265

Zengler K., Heider J., Rosselló-Mora R. & Widdel F. (1999) Phototrophic utilisation of toluene under anoxic conditions by a new strain of Blastochloris sulfoviridis. Arch. Microbiol. 172, 204-212. DOI: 10.1007/s002030050761

1998

Heider J., Boll M., Breese K., Breinig S., Ebenau-Jehle C., Feil U., Gad’on N., Laempe D., Leuthner B., Mohamed M., Schneider S., Burchhardt G. & Fuchs G. (1998) Differential induction of enzymes involved in anaerobic metabolism of aromatic compounds in the denitrifying bacterium Thauera aromatica. Arch. Microbiol. 170, 120-131. DOI: 10.1007/s002030050623

Leuthner B. & Heider J. (1998) A two-component system involved in regulation of anaerobic toluene metabolism in Thauera aromatica. FEMS Microbiol. Lett. 166, 35-41. DOI: 10.1111/j.1574-6968.1998.tb13180.x

Leuthner B., Leutwein C., Schulz H., Hörth P., Haehnel H., Schiltz E., Schägger H. & Heider J. (1998) Biochemical and genetic characterisation of benzylsuccinate synthase from Thauera aromatica: a new glycyl-radical enzyme catalysing the first step in anaerobic toluene metabolism. Molec. Microbiol. 28, 615-628. DOI: 10.1046/j.1365-2958.1998.00826.x

 Rabus R. & Heider J. (1998) Initial reactions of anaerobic metabolism of alkylbenzenes in denitrifying and sulfate-reducing bacteria. Arch. Microbiol. 170, 377-384. DOI: org/10.1007/s002030050656

1997

Müller S., Heider J. & Böck A. (1997) The path of unspecific incorporation of selenium in Escherichia coli. Arch. Microbiol. 168, 421-427. DOI: 10.1007/s002030050517

1996

Biegert T., Fuchs G. & Heider J. (1996) Evidence that anaerobic oxidation of toluene in the denitrifying bacterium Thauera aromatica is initiated by formation of benzylsuccinate from toluene and fumarate, Eur. J. Biochem. 238, 661-668. DOI: 10.1111/j.1432-1033.1996.0661w.x

Heider J., Mai X. & Adams M. W. W. (1996) Characterisation of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A dependent enzyme involved in peptide fermentation by hyperthermophilic archaea. J. Bacteriol. 178, 780-787. DOI: 10.1128/jb.178.3.780-787.1996

Hüttenhofer A., Heider J. & Böck A. (1996) Interaction of the Escherichia coli fdhF hairpin promoting selenocysteine incorporation with the ribosome. Nucl. Acids Res. 24, 3903-3910. DOI: 10.1093/nar/24.20.3903

1995

Heider J., Ma K. & Adams M. W. W. (1995) Purification, characterisation and metabolic function of tungsten-containing aldehyde ferredoxin oxidoreductase from the hyperthermophilic archaeon Thermococcus strain ES-1. J. Bacteriol. 177, 4757-4764. DOI: 10.1128/jb.177.16.4757-4764.1995

Ma K., Loessner H., Heider J., Johnson M. K. & Adams M. W. W. (1995) Effects of elemental sulfur on the metabolism of the deep-sea hyperthermophilic archaeon Thermococcus strain ES-1: characterisation of a sulfur-regulated, non-heme iron alcohol dehydrogenase. J. Bacteriol. 177, 4748-4756. DOI: 10.1128/jb.177.16.4748-4756.1995

1994

Tormay P., Wilting R., Heider J. & Böck A. (1994) Genes coding for the selenocysteine-inserting tRNA species from Desulfomicrobium baculatum and Clostridium thermoaceticum: structural and evolutionary implications. J. Bacteriol. 176, 1268-1274. DOI: 10.1128jb.176.5.1268-1274.1994

1993

Baron C., Heider J. & Böck A. (1993) Interaction of translation factor SELB with the formate dehydrogenase H selenopolypeptide mRNA. Proc. Natl. Acad. Sci. USA 90, 4181-4185. DOI: 10.1073/pnas.90.9.4181

1992

Heider J., Baron C. & Böck A. (1992) Coding from a distance: dissection of the mRNA determinants required for the incorporation of selenocysteine into protein. EMBO J. 11, 3759-3766. PMCID: doi.org/10.1002/j.1460-2075.1992.tb05461.x

Heider J. & Böck A. (1992) Targeted insertion of selenocysteine into the a-subunit of formate dehydrogenase from Methanobacterium formicicum. J. Bacteriol. 174, 659-663. DOI: 10.1128/jb.174.3.659-663.1992

1991

Berg B. L., Li J., Heider J. & Stewart V. (1991) Nitrate-inducible formate dehydrogenase in Escherichia coli K-12: I. Nucleotide sequence of the fdnGHI operon and evidence that opal (UGA) encodes selenocysteine. J. Biol. Chem. 266, 22380-22385. DOI: org/10.1016/S0021-9258(18)54583-X

Heider J., Forchhammer K., Sawers G. & Böck A. (1991) Interspecies compatibility of selenoprotein biosynthesis in Enterobacteriaceae. Arch. Microbiol. 155, 221-228. DOI: 10.1128/jb.173.16.4983-4993.1991

Sawers G., Heider J., Zehelein E. & Böck A. (1991) Expression and operon structure of the sel genes of Escherichia coli and identification of a third selenium-containing formate dehydrogenase isoenzyme. J. Bacteriol. 173, 4983-4993. DOI: 10.1128/jb.173.16.4983-4993.1991

1990

Baron C., Heider J. & Böck A. (1990) Mutagenesis of selC, the gene for the selenocysteine-inserting tRNA-species in E. coli: effects on in vivo function. Nucl. Acids Res. 18, 6761-6766. DOI: 10.1093/nar/18.23.6761

Zinoni F., Heider J. & Böck A. (1990) Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine. Proc. Natl. Acad. Sci. USA 87, 4660-4664. DOI: 10.1073/pnas.87.12.4660

1989

Heider J., Leinfelder W. & Böck A. (1989) Occurrence and functional compatibility of a tRNA species which inserts selenocysteine into protein. Nucl. Acids Res. 17, 2529-2540. DOI: 10.1093/nar/17.7.2529

Reviews

2020

Seelmann C. S., Willistein M., Heider, J. & Boll M. (2020) Tungstoenzymes: occurrence, catalytic diversity and cofactor synthesis. Inorganics 8, 44. DOI: 10.3390/inorganics8080044

2018

Czech L., Hermann L., Stöveken N., Richter A. A., Höppner A., Smits S. H. J., Heider J., Bremer E. (2018) Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry and structural analysis. Genes 9, E177. DOI: 10.3390/genes9040177

Boll M., Estelmann S. & Heider J. (2018) Catabolic pathways and enzymes involved in the anaerobic degradation of monocyclic aromatic compounds. In: Boll M. (ed) Anaerobic Utilization of Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer, Cham. DOI: 10.1007/978-3-319-33598-8_6-1

Boll M., Estelmann S. & Heider J. (2018) Anaerobic Degradation of Hydrocarbons: Mechanisms of Hydrocarbon Activation in the Absence of Oxygen. In: Boll M. (ed) Anaerobic Utilization of Hydrocarbons, Oils, and Lipids. Handbook of Hydrocarbon and Lipid Microbiology. Springer, Cham. DOI: 10.1007/978-3-319-33598-8_2-1

2016

Rabus R., Boll M., Heider J., Meckenstock R. U., Buckel W., Einsle O., Ermler U.,   Golding B. T.,  Gunsalus R., Kroneck P. M. H., Krüger M., Lueders T., Martins B. M.,  Musat F., Richnow H. H., Schink B., Seifert J., Szaleniec M., Treude T., Ullmann G. M., Vogt C.,  von Bergen M. & Wilkes H. (2016) Anaerobic Microbial Degradation of Hydrocarbons  -  From Enzymatic Reactions to the Environment. J. Mol. Microbiol. Biotechnol. 26, 5-28. DOi: 10.1159/000443997
 

Heider J., Szaleniec M., Martins B. M., Seyhan D., Buckel W. & Golding B. T. (2016) Structure and function of benzylsuccinate synthase and related fumarate-adding glycyl radical enzymes. J. Mol. Microbiol. Biotechnol. 26, 29-44. DOI: 10.1159/000441656

Heider J., Szaleniec M., Sünwoldt K. & Boll M. (2016) Ethylbenzene dehydrogenase and related molybdenum enzymes involved in oxygen-independent alkyl chain hydroxylation. J. Mol. Microbiol. Biotechnol. 26, 45-62. DOI: 10.1159/000441357

Heider J., Schühle K., Frey J. & Schink B. & (2016) Activation of acetone and other ketones in anaerobic bacteria. J. Mol. Microbiol. Biotechnol. 26, 152-164. DOI: 10.1159/000441500

2015

Heider J. & Fuchs G. (2015) Thauera. In: Bergey's Manual of Systematics of Archaea and Bacteria (W. B. Whitman ed.), John Wiley & Sons, Inc., in association with Bergey's Manual Trust. DOI: 10.1002/9781118960608.gbm01004

2013

Heider J. & Schühle K. (2013) Anaerobic biodegradation of hydrocarbons including methane. In: The Prokaryotes: Prokaryotic Physiology and Biochemistry., 4th ed. (Rosenberg E., DeLong E.F., Thompson F., Lory S., Stackebrandt E. eds), Chapter 80, pp. 601-630, Springer-Verlag, Heidelberg. DOI: 10.1007/978-3-642-30141-4_80

2011

Fuchs G., Boll M. & Heider J. (2011) Microbial degradation of aromatic compounds – from one strategy to four. Nature Rev. Microbiol. 9, 803-816. DOI: 10.1038/nrmicro2652 

2009

Boll M. & Heider J. (2009) Anaerobic Degradation of Hydrocarbons: Mechanisms of C-H-bond activation in the absence of oxygen. In: Handbook of Hydrocarbon and Lipid Microbiology (K. N. Timmis ed.),  pp. 1011-1024, Springer-Verlag, Heidelberg. DOI: 10.1007/978-3-540-77587-4_71

2008

Heider J. (2008) Bakterieller Kohlenwasserstoff-Abbau—es geht auch ohne Sauerstoff. Biospektrum 14, 28-31

Heider J. & Rabus R. (2008) Genomic insights in the anaerobic biodegradation of organic pollutants. In: Microbial biodegradation: Genomics and molecular biology (E. Diaz ed.), pp. 25-54, Caister academic press, Norfolk, UK

2007

Heider J. (2007) Adding handles to unhandy substrates: anaerobic hydrocarbon activation mechanisms. Curr. Opin. Chem. Biol. 11, 188-194. DOI: 10.1016/j.cbpa.2007.02.027

2005

Selmer T., Pierik A. J., Heider J. (2005) New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria. Biol. Chem. 386, 981-988. DOI: 10.1515/BC.2005.114

Heider J. & Fuchs G. (2005) Genus Thauera. In: Bergey’s Manual of Systematic Bacteriology (2nd ed); Vol. 2, part C (G. Garitty, ed.), pp. 907-913, Springer Verlag, Berlin

2002

Boll M., Fuchs G. & Heider J. (2002) Anaerobic oxidation of aromatic compounds and hydrocarbons. Curr. Opin. Chem. Biol. 6, 604-611. DOI: 10.1016/s1367-5931(02)00375-7

2001

Heider J. (2001) A new family of CoA-transferases. FEBS Lett. 509, 345-349. DOI: 10.1016/s0014-5793(01)03178-7

2000

Heider J. (2000) Toluol-Stoffwechsel ohne Sauerstoff: eine (Glycyl-)radikale Lösung. Biospektrum 6, 280-281

1998

Heider J., Spormann, A. M., Beller H. R. & Widdel, F. (1998) Anaerobic bacterial metabolism of hydrocarbons. FEMS Microbiol. Rev. 22, 459-473. DOI: 10.1111/j.1574-6976.1998.tb00381.x

1997

Heider J. & Fuchs G. (1997) Anaerobic metabolism of aromatic compounds, Eur. J. Biochem. 243, 577-596. DOI: 10.1111/j.1432-1033.1997.00577.x

Heider J. & Fuchs G. (1997) Microbial anaerobic aromatic metabolism, Anaerobe 3, 1-22. DOI: 10.1006/anae.1997.0073 

1993

Heider J. & Böck A. (1993) Selenium metabolism in micro-organisms. Adv. Microb. Physiol. 35, 71-109. DOI: 10.1016/s0065-2911(08)60097-1

1991

Böck A., Forchhammer K., Heider J. & Baron C. (1991) Selenoprotein synthesis: an expansion of the genetic code. Trends Biochem. Sci. 16, 463-467. DOI: 10.1016/0968-0004(91)90180-4

Böck A., Forchhammer K., Heider J., Leinfelder W., Sawers G., Veprek B. & Zinoni F (1991) Selenocysteine: the 21st amino acid. Molec. Microbiol. 5, 515-520. DOI: 10.1111/j.1365-2958.1991.tb00722.x

1990

Böck A., Baron C., Forchhammer K., Heider J., Leinfelder W., Sawers G., Veprek B., Zehelein E. & Zinoni F. (1990) From nonsense to sense: UGA encodes selenocysteine in formate dehydrogenase and other selenoproteins. In: 41. Colloquium Mosbach: The molecular basis of bacterial metabolism (G. Hauska & R. Thauer eds.), pp. 61-68, Springer Verlag, Berlin

Patente

Luo S., Erb T. & Heider J. (2023) ATP production from electricity with a new-to-nature electrobiological module

Winiarska A., Szaleniec M., Heider J., Hege D., Arndt F., Wojtkiewicz A. (2022) A method of enzymatic reduction of the oxidized nicotinamide adenine dinucleotide and carboxylic acids. EP Patent Application Pub. No. EP22164459; EP4092126A1

Winiarska A., Heider J., Szaleniec M., Hege D., Arndt F. (2021) Sposób enzymatycznej redukcji formy utlenionej dinukleotydu nikotynowo-adeninowego (Method of enzymatic reduction of the oxidized form of nicotine adenine dinucleotide). Polish Patent Application Pub. No. P.437449; PL437449A1

Winiarska A., Heider J., Szaleniec M., Hege D., Arndt F. (2021) Sposób otrzymywania aldehydów poprzez enzymatyczną redukcję kwasów karboksylowych (Method of obtaining aldehydes by enzymatic reduction of carboxylic acids). Polish Patent Application Pub. No. P.437445; PL437445A1 

Stürmer R., Schneider N., Boy M., Achatz B., Rabus R., Heider J, (2011) Method for preparing optically active hydroxy acid esters. Application No.:  PCT/EP2010/060458, Pub No WO002011009849A2 

Breuer M., Rabus R., Heider J. (2010) Method for production of optically active alcohols using an Azoarcus sp. EbN1 dehydrogenase. Intl. Appl. No. PCT/EP2008/057522, Pub. Nos. CA000002691799A1, CN000101796192A, EP000002171074A1, MX002009014055A, US020100143991A1, WO002008155302A1 

Candussio A., Amann M., Wich G., Heider J. (2008) Method for effecting the anaerobic biological decomposition of organosiloxanes. Appl Nr EP20050715924, Pub. Nos. EP000001749100B1, EP000001749100A1, WO002005087939A1 

Fischer M., Heider J. (2007) Verfahren zum anaeroben Abbau von organo-funktionalisierten Silicium-Verbindungen, Silanen und Siloxanen durch Bakterien. Appl No 102006007292, Pub No DE102006007292A1 

Fischer M., Heider J. (2007) Verfahren zum anaeroben Abbau von Organosilicium-Verbindungen durch Bakterien der Gattung Paracoccus. Appl No 2007051116, Pub No WO002007093523A1 

Candussio A., Amann M., Wich G., Heider J. (2005) Anaerober Abbau von Polyorganosiloxanen und Organosilanen. Appl No 102004011993,  Pub No DE102004011993A1