Bette M, Reinhardt L, Gansukh U, Xiang-Tischhauser L, Meskeh H, Di Fazio P, Buchholz M, Stuck BA, Mandic R. The Role of TGF-b1 and Mutant SMAD4 on Epithelial-Mesenchymal Transition Features in Head and Neck Squamous Cell Carcinoma Cell Lines. Cancers (Basel). 2024 Sep 16;16(18):3172. doi: 10.3390/cancers16183172. PMID: 39335144; PMCID: PMC11429651.
Krause FF, Mangold KI, Ruppert AL, Leister H, Hellhund-Zingel A, Lopez Krol A, Pesek J, Watzer B, Winterberg S, Raifer H, Binder K, Kinscherf R, Walker A, Nockher WA, Taudte RV, Bertrams W, Schmeck B, Kühl AA, Siegmund B, Romero R, Luu M, Göttig S, Bekeredjian-Ding I, Steinhoff U, Schütz B, Visekruna A (2024) Clostridium sporogenes-derived metabolites protect mice against colonic inflammation. Gut Microbes 16 (1), 2412669, doi: 10.1080/19490976.2024.2412669
Keshavarz M, Ruppert AL, Meiners M, Poharkar K, Liu S, Mahmoud W, Winterberg S, Hartmann P, Mermer P, Perniss A, Offermanns S, Kummer W, Schütz B. Bitter tastants relax the mouse gallbladder smooth muscle independent of signaling through tuft cells and bitter taste receptors. Sci. Rep. 2024 14(1):18447. doi: 10.1038/s41598-024-69287-6.
Rinné S, Kiper AK, Jacob R, Ortiz-Bonnin B, Schindler RFR, Fischer S, Komadowski M, De Martino E, Schäfer MK, Cornelius T, Fabritz L, Helker CSM, Brand T, Decher N. Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5. iScience. 2024 Apr 9;27(5):109696. doi: 10.1016/j.isci.2024.109696 . eCollection 2024 May 17
Kiper AK, Wegner S, Kadala A, Rinné S, Schütte S, Winter Z, Bertoune MAR, Touska F, Matschke V, Wrobel E, Streit AK, Lang F, Schmidt C, Schulze-Bahr E, Schäfer MK, Voelkl J, Seebohm G, Zimmermann K, Decher N. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2322475121. doi: 10.1073/pnas.2322475121 . Epub 2024 Jun 10.
2023
Ali U, Bette M, Ambreen G, Pinnapireddy SR, Tariq I, Marquardt A, Stuck BA, Bakowsky U, Mandic R. RNAi-Mediated Knockdown of Cottontail Rabbit Papillomavirus Oncogenes Using Low-Toxicity Lipopolyplexes as a Paradigm to Treat Papillomavirus-Associated Cancers. Pharmaceutics. 2023 Sep 25;15(10):2379. doi: 10.3390/pharmaceutics15102379. PMID: 37896139; PMCID: PMC10610439.
Koehler U, Degerli MA, Conradt R, Hildebrandt O, Koehler N, Hildebrandt W. The search for the "node of life": breathing regulation. Pneumologie. 2023 Dec 14. doi: 10.1055/a-2215-2937.
Xiang-Tischhauser L, Bette M, Rusche JR, Roth K, Kasahara N, Stuck BA, Bakowsky U, Wartenberg M, Sauer H, Geisthoff UW, Mandic R. Generation of a Syngeneic Heterozygous ACVRL1(wt/mut) Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis. Cells. 2023 Jun 10;12(12):1600. doi: 10.3390/cells12121600. PMID: 37371070; PMCID: PMC10297623.
Perniss A, Boonen B, Tonack S, Thiel M, Poharkar K, Alnouri MW, Keshavarz M, Papadakis T, Wiegand S, Pfeil U, Richter K, Althaus M, Oberwinkler J, Schütz B, Boehm U, Offermanns S, Leinders-Zufall T, Zufall F, Kummer W. A succinate/SUCNR1-brush cell defense program in the tracheal epithelium. Sci Adv 9, eadg8842 (2023). DOI: 10.1126/sciadv.adg8842
Schmich SKP, Keck J, Bonaterra GA, Bertoune M, Adam A, Wilhelm B, Slater EP, Schwarzbach H, Fendrich V, Kinscherf R, Hildebrandt W. Effects of Monoamino-Oxidase-A (MAO-A) Inhibition on Skeletal Muscle Inflammation and Wasting through Pancreatic Ductal Adenocarcinoma in Triple Transgenic Mice. Biomedicines. 2023 Mar 15;11(3):912. doi: 10.3390/biomedicines11030912. PMID: 36979889 Free PMC article.
Luu M, Schütz B, Lauth M, Visekruna A. The Impact of Gut Microbiota-Derived Metabolites on the Tumor Immune Microenvironment. Cancers (Basel). 2023 Mar 3;15(5):1588. doi: 10.3390/cancers15051588.
Margulies O, Nübling M, Verheul W, Hildebrandt W, Hildebrandt H. Determining factors for compensatory movements of the left arm and shoulder in violin playing. Front Psychol. 2023 Jan 23;13:1017039. doi: 10.3389/fpsyg.2022.1017039.
2022
Koehler U, Conradt R, Hildebrandt W. Langhans' or Langerhans' cells? - The problem of the eponym. Dtsch Med Wochenschr. 2022 Dec;147(24-25):1590-1595. doi: 10.1055/a-1884-7518. Epub 2022 Dec 5.
Koehler U, Hildebrandt O, Conradt R, Koehler J, Hildebrandt W. The bronchial arteries: a small but vital contribution to lung perfusion after lung transplantation. Pneumologie. 2022 Aug;76(8):552-559. doi: 10.1055/a-1845-0286. Epub 2022 Jul 25.
Bonaterra GA, Schmitt J, Schneider K, Schwarzbach H, Aziz-Kalbhenn H, Kelber O, Müller J, Kinscherf R. Phytohustil® and root extract of Althaea officinalis L. exert anti-inflammatory and anti-oxidative properties and improve the migratory capacity of endothelial cells in vitro. Front Pharmacol. 2022 Dec 8;13:948248. doi: 10.3389/fphar.2022.948248. eCollection 2022. PMID: 36569306 Free PMC article.
Berz A, Pasquini de Souza C, Wöhr M, Steinmüller S, Bruntsch M, Schäfer MK, Schwarting RKW. Contingent Social Interaction Does Not Prevent Habituation towards Playback of Pro-Social 50-kHz Calls: Behavioral Responses and Brain Activation Patterns. Brain Sci. 2022 Oct 31;12(11):1474. doi: 10.3390/brainsci12111474.
Bonaterra GA, Schleper A, Skowronek M, Kilian LS, Rink T, Schwarzbach H, Heers H, Hänze J, Rexin P, Ramaswamy A, Denkert C, Wilhelm B, Hegele A, Hofmann R, Weihe E, Kinscherf R. Increased Density of Growth Differentiation Factor-15+ Immunoreactive M1/M2 Macrophages in Prostate Cancer of Different Gleason Scores Compared with Benign Prostate Hyperplasia. Cancers (Basel). 2022 Sep 22;14(19):4591. doi: 10.3390/cancers14194591.
Halbgebauer R, Halbgebauer S, Oeckl P, Steinacker P, Weihe E, Schaefer M, Roselli F, Gebhard F, Huber-Lang M, Otto M. Neurochemical monitoring of traumatic brain injury by the combined analysis of plasma beta-synuclein, NfL and GFAP in polytraumatized patients. IJMS. 2022.
Mandic R, Marquardt A, Terhorst P, Ali U, Nowak-Rossmann A, Cai C, Rodepeter FR, Stiewe T, Wezorke B, Wanzel M, Neff A, Stuck BA, Bette M. The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC. BMC Cancer. 2022 Jul 18;22(1):785. doi: 10.1186/s12885-022-09854-0. PMID: 35850701; PMCID: PMC9290296.
Mercurio D, Fumagalli S, Schafer MK, Pedragosa J, Ngassam LDC, Wilhelmi V, Winterberg S, Planas AM, Weihe E, De Simoni MG. Protein Expression of the Microglial Marker Tmem119 Decreases in Association With Morphological Changes and Location in a Mouse Model of Traumatic Brain Injury. Front Cell Neurosci. 2022 Feb 10;16:820127. doi: 10.3389/fncel.2022.820127. eCollection 2022.
Mandic R, Agaimy A, Pinto-Quintero D, Roth K, Teymoortash A, Schwarzbach H, Stoehr CG, Rodepeter FR, Stuck BA, Bette M. Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. Cancers (Basel). 2020 Apr 29;12(5):1112. doi: 10.3390/cancers12051112.
Luu M, Binder K, Hartmann S, Kespohl M, Bazant J, Romero R, Schütz B, Steinhoff U, Visekruna A. Transcription factor c-Rel mediates communication between commensal bacteria and mucosal lymphocytes. J Leukoc Biol. 2022 May;111(5):1001-1007. doi: 10.1002/JLB.3AB0621-350R. Epub 2021 Oct 8.
Hildebrandt W, Keck J, Schmich S, Bonaterra GA, Wilhelm B, Schwarzbach H, Eva A, Bertoune M, Slater EP, Fendrich V, Kinscherf R. Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer-When Does Cachexia Start? Cells. 2022 May 11;11(10):1607. doi: 10.3390/cells11101607. PMID: 35626644
Hehrlein C, Schorch B, Haberstroh J, Bode C, Mey L, Schwarzbach H, Kinscherf R, Meckel S, Schiestel S, Kovacs A, Fischer H, Nennig E. Bioresorbable zinc stent with ultra-thin center struts attenuates stent jail in porcine femoral artery bifurcations. Minim Invasive Ther Allied Technol. 2022 Jan;31(1):72-79. doi: 10.1080/13645706.2020.1770797. Epub 2020 Jun 13.
Bannow LI, Bonaterra GA, Bertoune M, Maus S, Schulz R, Weissmann N, Kraut S, Kinscherf R, Hildebrandt W. Effect of chronic intermittent hypoxia (CIH) on neuromuscular junctions and mitochondria in slow- and fast-twitch skeletal muscles of mice-the role of iNOS. Skelet Muscle. 2022 Feb 12;12(1):6. doi: 10.1186/s13395-022-00288-7. PMID: 35151349 Free PMC article.
Bette M, Cors E, Kresse C, Schütz B. Therapeutic treatment of superoxide dismutase 1 (G93A) amyotrophic lateral sclerosis model mice with medical ozone decelerates trigeminal motor neuron degeneration, attenuates microglial proliferation, and preserves monocyte levels in mesenteric lymph nodes. Int J Mol Sci 2022, 23, 3403, doi:10.3390/ijms23063403.
Keshavarz M, Faraj Tabrizi S, Ruppert A-L, Pfeil U, Schreiber Y, Klein J, Brandenburger I, Lochnit G, Bhushan S, Perniss A, Deckmann K, Hartmann P, Meiners M, Mermer P, Rafiq A, Winterberg S, Papadakis T, Thomas D, Angioni C, Oberwinkler J, Chubanov V, Gudermann T, Gärtner U, Offermanns S, Schütz B, Kummer W. Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. Sci Immunol 2022, Mar 4;7(69):eabf6734, doi:10.1126/sciimmunol.abf6734.
2021
Bonaterra GA, Struck N, Zügel S, Schwarz A, Mey L, Schwarzbach H, Strelau J, Kinscherf R. Characterization of atherosclerotic plaques in blood vessels with low oxygenated blood and blood pressure (Pulmonary trunk): Role of growth differentiation factor -15 (GDF-15). BMC Cardiovascular Disorders 2021 Dec 17;21(1):601. doi: 10.1186/s12872-021-02420-9.
Wernhart S, Weihe E, Rassaf T. Reduced physical activity and weight gain are associated with an increase of depressive symptoms during the COVID-19 pandemic. A general practitioners' prospective observational study. JRSM Cardiovasc Dis. 2021 Oct 1;10:20480040211047742. doi: 10.1177/20480040211047742. eCollection 2021 Jan-Dec. PMID: 34631041.
Wernhart S, Hedderich J, Weihe E. Vital capacity and valvular dysfunction could serve as non-invasive predictors to screen for exercise pulmonary hypertension in the elderly based on a new diagnostic score. J Cardiovasc Thorac Res. 2021;13(1):68-78. doi: 10.34172/jcvtr.2021.05. Epub 2021 Jan 30. PMID: 33815705.
Wernhart S, Hedderich J, Wunderlich S, Schauerte K, Weihe E, Dellweg D, Siemon K. The Feasibility of High-Intensity Interval Training in Patients with Intensive Care Unit-Acquired Weakness Syndrome Following Long-Term Invasive Ventilation. Sports Med Open. 2021 Feb 1;7(1):11.
Wernhart S, Förster TH, Weihe E. Outpatient Management of Oligosymptomatic Patients with respiratory infection in the era of SARS-CoV-2: Experience from rural German general practitioners. BMC Infect Dis. 2020 Nov 6;20(1):811. doi: 10.1186/s12879-020-05538-x. PMID: 33158425.
Heduschke A, Ackermann K, Wilhelm B, Mey L, Bonaterra GA, Kinscherf R, Schwarz A. GDF-15 Deficiency Reduces Autophagic Activity in Human Macrophages In Vitro and Decreases p62-Accumulation in Atherosclerotic Lesions in Mice. Cells. 2021 Sep 7;10(9):2346. doi: 10.3390/cells10092346.
Luu M, Binder K, Hartmann S, Kespohl M, Bazant J, Romero R, Schütz B, Steinhoff U, Visekruna A (2021) Transcription factor c-Rel mediates communication between commensal bacteria and mucosal lymphocytes. J. Leukoc. Biol. doi: 10.1002/JLB.3AB0621-350R. Online ahead of print.
Perniss A, Schmidt P, Soultanova A, Papadakis T, Dahlke K, Voigt A, Schütz B, Kummer W, Deckmann K. Development of epithelial cholinergic chemosensory cells of the urethra and trachea of mice. Cell Tissue Res. 2021; https://doi.org/10.1007/s00441-021-03424-9.
Boneberg R, Pardun A, Hannemann L, Hildebrandt O, Koehler U, Kinscherf R, Hildebrandt W. High Plasma Cystine Levels Are Associated with Blood Pressure and Reversed by CPAP in Patients with Obstructive Sleep Apnea. J Clin Med. 2021 Mar 30;10(7):1387. doi: 10.3390/jcm10071387.
Laur N, Kaiser L, Deigner HP, Kinscherf R. Sequential Analysis of Trace Elements in a Micro Volume Urine Sample Using Inductively Coupled Plasma Mass Spectrometry. Appl. Sci. 2021, 11, 3740. https://doi.org/10.3390/app11093740.
Koehler U, Beutel B, Hildebrandt W. Salerno, the first medical school in Europe - Birthplace of university medicine. Dtsch Med Wochenschr. 2021 Dec;146(24-25):1593-1597. doi: 10.1055/a-1467-9256. Epub 2021 Dec 8. PMID: 34879408.
Koehler U, Hildebrandt O, Conradt R, Koehler J, Hildebrandt W. The Road to Discovery of the Pulmonary Gas Exchange - From the "Phlogiston-" to the "Oxygen Theory". Pneumologie. 2021 Oct 28. doi: 10.1055/a-1579-8387. Online ahead of print. PMID: 34710936.
Hildebrandt H, Margulies O, Köhler B, Nemcova M, Nübling M, Verheul W, Hildebrandt W. Muscle Activation and Subjectively Perceived Effort in Typical Violin Positions. Med Probl Perform Art. 2021 Sep;36(3):207-217. doi: 10.21091/mppa.2021.3023.PMID: 34464966.
Conradt R, Redhardt F, Beutel B, Hildebrandt O, Cassel W, Kesper K, Koehler J, Hildebrandt W, Koehler U. Predisposing factors of daytime sleepiness in obese OSA patients. J Sleep Res. 2021 Aug 7:e13458. doi: 10.1111/jsr.13458. Online ahead of print. PMID: 34363265.
Koenig AM, Koehler U, Hildebrandt O, Schwarzbach H, Hannemann L, Boneberg R, Heverhagen JT, Mahnken AH, Keller M, Kann PH, Deigner HP, Laur N, Kinscherf R, Hildebrandt W. The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men. J Endocr Soc. 2021 May 6;5(8):bvab082. doi: 10.1210/jendso/bvab082. eCollection 2021 Aug 1. PMID: 34268461 Free PMC article.
Koehler U, Hildebrandt O, Koehler J, Hildebrandt W. From the anatomical teaching dissection to tuition at the bedside-A historical appraisal. Wien Med Wochenschr. 2021 Jun;171(9-10):214-220. doi: 10.1007/s10354-021-00836-8. Epub 2021 Apr 14. PMID: 33852091 Free PMC article.
Boneberg R, Pardun A, Hannemann L, Hildebrandt O, Koehler U, Kinscherf R, Hildebrandt W. High Plasma Cystine Levels Are Associated with Blood Pressure and Reversed by CPAP in Patients with Obstructive Sleep Apnea. J Clin Med. 2021 Mar 30;10(7):1387. doi: 10.3390/jcm10071387. PMID: 33808409 Free PMC article.
Biollaz J, Buclin T, Hildebrandt W, Décosterd LA, Nussberger J, Swenson ER, Bärtsch PJ. No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent. J Appl Physiol (1985). 2021 Jan 1;130(1):226-236. doi: 10.1152/japplphysiol.00382.2020. Epub 2020 Nov 12. PMID: 33180647 Free article.
Koehler U, Hildebrandt O, Hildebrandt W, Aumüller G. Historical (cultural) view of the heart and cardiovascular system. Herz. 2021 Apr;46(Suppl 1):33-40. doi: 10.1007/s00059-020-04914-2. Epub 2020 Apr 14. PMID: 32291485 Free PMC article.
2020
Ruppert AL, Keshavarz M, Winterberg S, Oberwinkler J, Kummer W, Schütz B. Advillin is a tuft cell marker in the mouse alimentary tract. J. Mol. Hist. 2020, 51(4), 421-435; doi: 10.1007/s10735-020-09893-6.
Ehrenreich J, Bette M, Schmidt A, Roeßler M, Bakowsky U, Geisthoff U, Stuck BA, Mandic R. Evaluation of digital image analysis as a supportive tool for the stratification of head and neck vascular anomalies. Eur Arch Otorhinolaryngol. 2020; doi: 10.1007/s00405-020-06097-2.
Laur N, Kinscherf R, Pomytkin K, Kaiser L, Knes O, Deigner HP. ICP-MS trace element analysis in serum and whole blood. PLoS One. 2020 May 20;15(5):e0233357. doi: 10.1371/journal.pone.0233357. eCollection 2020. PMID: 32433650 Free article.
Bonaterra GA, Bronischewski K, Hunold P, Schwarzbach H, Heinrich EU, Fink C, Aziz-Kalbhenn H, Müller J, Kinscherf R. Anti-inflammatory and Anti-oxidative Effects of Phytohustil® and Root Extract of Althaea officinalis L. on Macrophages in vitro. Front Pharmacol. 2020 Mar 17;11:290. doi: 10.3389/fphar.2020.00290. eCollection 2020. PMID: 32256361 Free PMC article.
Splitthoff P, Rasbach E, Neudert P, Bonaterra GA, Schwarz A, Mey L, Schwarzbach H, Eiden LE, Weihe E, Kinscherf R. PAC1 deficiency attenuates progression of atherosclerosis in ApoE deficient mice under cholesterol-enriched diet. Immunobiology. 2020 Feb 29:151930. doi: 10.1016/j.imbio.2020.151930. Online ahead of print.
Mandic R, Agaimy A, Pinto-Quintero D, Roth K, Teymoortash A, Schwarzbach H, Stoehr CG, Rodepeter FR, Stuck BA, Bette M. Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors. Cancers (Basel). 2020 Apr 29;12(5): E1112. doi: 10.3390/cancers12051112.
Perniss A, Liu S, Boonen B, Keshavarz M, Ruppert AL, Timm T, Pfeil U, Soultanova A, Kusumakshi S, Delventhal L, Aydin Ö, Pyrski M, Deckmann K, Hain T, Schmidt N, Ewers C, Günther A, Lochnit G, Chubanov V, Gudermann T, Oberwinkler J, Klein J, Mikoshiba K, Leinders-Zufall T, Offermanns S, Schütz B, Boehm U, Zufall F, Bufe B, Kummer W. Chemosensory cell-derived acetylcholine drives tracheal mucociliary clearance in response to virulence-associated formyl peptides. Immunity 2020;52(4):683-699. doi:10.1016/j.immuni.2020.03.005.
Ambreen G, Duse L, Tariq I, Ali U, Ali S, Pinnapireddy SR, Bette M, Bakowsky U, Mandic R. (2020) “Sensitivity of Papilloma Virus-Associated Cell Lines to Photodynamic Therapy with Curcumin-Loaded Liposomes.” Cancers (Basel). 2020 Nov 5;12(11):E3278. doi: 10.3390/cancers12113278
Bonaterra GA, Bender K, Wilhelm B, Schwarzbach H, Metz S, Kelber O, Weiser D, Metz J, Kinscherf R. Effect of cholesterol re-supplementation and atorvastatin on plaque composition in the thoracic aorta of New Zealand white rabbits. BMC Cardiovasc Disord. 2020 Sep 17;20(1):420. doi: 10.1186/s12872-020-01703-x.
Biollaz J, Buclin T, Hildebrandt W, Décosterd LA, Nussberger J, Swenson ER, Bärtsch P. No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent. J Appl Physiol (1985). 2020 Nov 12. doi: 10.1152/japplphysiol.00382.2020. Online ahead of print. PMID: 33180647
Koehler U, Hildebrandt O, Hildebrandt W, Aumüller G. Herz.[Historical (cultural) view of the heart and cardiovascular system]. 2020 Apr 14. doi: 10.1007/s00059-020-04914-2. Online ahead of print. PMID: 32291485 Review. German.
Bonaterra GA, Mierau O, Hofmann J, Schwarzbach H, Aziz-Kalbhenn H, Kolb C, Kinscherf R. In Vitro Effects of St. John's Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia. Front Pharmacol. 2020 Dec 3;11:603575. doi: 10.3389/fphar.2020.603575. eCollection 2020. PMID: 33628177 Free PMC article.
Dierich M, Altoè A, Koppelmann J, Evers S, Renigunta V, Schäfer MK, Naumann R, Verhulst S, Oliver D, Leitner MG. Optimized Tuning of Auditory Inner Hair Cells to Encode Complex Sound through Synergistic Activity of Six Independent K+ Current Entities. Cell Rep. 2020 Jul 7;32(1):107869. doi: 10.1016/j.celrep.2020.107869. PMID: 32640234.
2019
K. Ackermann, G.A. Bonaterra, R. Kinscherf, A. Schwarz. Growth differentiation factor-15 regulates oxLDL-induced lipid homeostasis and autophagy in human macrophages. Atherosclerosis 2019a. 281: 128-136. doi:10.1016/j.atherosclerosis.2018.12.009A.
K. Ackermann, G.A. Bonaterra, R. Kinscherf, A. Schwarz. Data on Autophagy Markers in Human Macrophages Exposed to OxLDL and Growth Differentiation Factor-15. Data in Brief 2019b.
Nejsum LN, Piec A, Fijak M, Ernstsen CV, Fischer D, Maier TJ, Kinscherf R, Hofmann R, Urbschat A. Systemic LPS induces toll-like receptor 3 (TLR3) expression and apoptosis in testicular mouse tissue. Cell Tissue Res. 2019 Apr 15. doi: 10.1007/s00441-019-03022-w. [Epub ahead of print]
Mey L, Jung M, Roos F, Blaheta R, Hegele A, Kinscherf R, Urbschat A. NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells. J Cancer Res Clin Oncol. 2019 Mar 22. doi: 10.1007/s00432-019-02901-7. [Epub ahead of print]
Rosemeyer H, Knies C, Hammerbacher K, Bender E, Bonaterra GA, Hannen R, Bartsch JW, Nimsky C, Kinscherf R. Nucleolipids of the Nucleoside Antibiotics Formycin A and B: Synthesis and Biomedical Characterization particularly using Glioblastoma Cells. Chem Biodivers. 2019 Feb 18. doi: 10.1002/cbdv.201900012. [Epub ahead of print]
Reuter H, van Bodegraven AM, Bender E, Knies C, Diek N, Beginn U, Hammerbacher K, Schneider V, Kinscherf R, Bonaterra GA, Svajda R, Rosemeyer H. Guanosine Nucleolipids: Synthesis, Characterization, Aggregation and X-Ray Crystallographic Identification of Electricity-Conducting G-Ribbons. Chem Biodivers. 2019 May;16(5):e1900024. doi: 10.1002/cbdv.201900024. Epub 2019 May 15.
Bonaterra GA, Schwarzbach H, Kelber O, Weiser D, Kinscherf R. Anti-inflammatory effects of Phytodolor® (STW 1) and components (poplar, ash and goldenrod) on human monocytes/macrophages. Phytomedicine. 2019 Feb 18;58:152868. doi: 10.1016/j.phymed.2019.152868. [Epub ahead of print]
Christine Knies, Hans Reuter, Katharina Hammerbacher, Eugenia Bender, Gabriel A. Bonaterra, Ralf Kinscherf, Helmut Rosemeyer. Synthesis of New Potential Lipophilic Co-Drugs of 2-Chloro-2’-deoxyadenosine (Cladribine, 2-CdA, Mavenclad®, Leustatin®) and 6-Azauridine (z6U) with Valproic Acid. Chem. Biodiversity 2019 Feb 18. doi: 10.1002/cbdv.201900012. [Epub ahead of print]
Ackermann K, Bonaterra GA, Kinscherf R, Schwarz A. Growth differentiation factor-15 regulates oxLDL-induced lipid homeostasis and autophagy in human macrophages. Atherosclerosis. 2018 Dec 19;281:128-136. doi: 10.1016/j.atherosclerosis.2018.12.009. [Epub ahead of print]
Rosemeyer H, Knies C, Reuter H, Hammerbacher K, Bender E, Bonaterra GA, Kinscherf R. Synthesis of New Potential Lipophilic Co-Drugs of 2-Chloro-2'-deoxyadenosine (Cladribine, 2CdA, Mavenclad®, Leustatin®) and 6-Azauridine (z6U) with Valproic Acid. Chem Biodivers. 2018 Dec 21. doi: 10.1002/cbdv.201800497. [Epub ahead of print]
Hehrlein C, Schorch B, Kress N, Arab A, von Zur Mühlen C, Bode C, Epting T, Haberstroh J, Mey L, Schwarzbach H, Kinscherf R, Stachniss V, Schiestel S, Kovacs A, Fischer H, Nennig E. Zn-alloy provides a novel platform for mechanically stable bioresorbable vascular stents. PLoS One. 2019 Jan 2;14(1):e0209111. doi: 10.1371/journal.pone.0209111.
Schütz B, Ruppert AL, Strobel O, Lazarus M, Urade Y, Büchler MW, Weihe E. Distribution pattern and molecular signature of cholinergic tuft cells in human gastro-intestinal and pancreatic-biliary tract. Sci Rep 2019;9(1):17466 doi: 10.1038/s41598-019-53997-3
2018
Rasbach E, Splitthoff P, Bonaterra GA, Schwarz A, Mey L, Schwarzbach H, Eiden LE, Weihe E, Kinscherf R. PACAP deficiency aggravates atherosclerosis in ApoE deficient mice. Immunobiology. 2018 Oct 26. pii: S0171-2985(18)30144-X. doi: 10.1016/j.imbio.2018.09.008. [Epub ahead of print]
Hänze J, Rexin P, Jakubowski P, Schreiber H, Heers H, Lingelbach S, Kinscherf R, Weihe E, Hofmann R, Hegele A. Prostate cancer tissues with positive TMPRSS2-ERG-gene-fusion status may display enhanced nerve density. Urol Oncol. 2018 Sep 18. pii: S1078-1439(18)30292-8. doi: 10.1016/j.urolonc.2018.07.019. [Epub ahead of print]
Ladel S, Flamm J, Zadeh AS, Filzwieser D, Walter JC, Schlossbauer P, Kinscherf R, Lischka K, Luksch H, Schindowski K. Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery? Pharmaceutics. 2018 Jul 26;10(3). pii: E107. doi: 10.3390/pharmaceutics10030107. PMID: 30050027.
Hammerbacher K, Görtemaker K, Knies C, Bender E, Bonaterra GA, Rosemeyer H, Kinscherf R. Combinatorial Synthesis of New Pyrimidine- and Purine-ß-D-Ribonucleoside Nucleolipids: Their Distribution Between Aqueous and Organic Phases and Their in vitro Activity Against Human- and Rat Glioblastoma Cells in vitro. Chem Biodivers. 2018 Jun 21. doi: 10.1002/cbdv.201800173. [Epub ahead of print] PMID: 29928783.
Bonaterra GA, Schwendler A, Hüther J, Schwarzbach H, Schwarz A, Kolb C, Abdel-Aziz H, Kinscherf R. Neurotrophic, Cytoprotective, and Anti-inflammatory Effects of St. John's Wort Extract on Differentiated Mouse Hippocampal HT-22 Neurons. Front Pharmacol. 2018 Jan 18;8:955. doi: 10.3389/fphar.2017.00955. eCollection 2017.
Koehler U, Hildebrandt O, Krönig J, Grimm W, Otto J, Hildebrandt W, Kinscherf R. Chronic hypoxia and cardiovascular risk : Clinical significance of different forms of hypoxia. Herz. 2018 Jun;43(4):291-297. doi: 10.1007/s00059-017-4570-5. Epub 2017 May 4. Review. German. PMID: 28474128.
2017
Blaess M, Bibak N, Claus RA, Kohl M, Bonaterra GA, Kinscherf R, Laufer S, Deigner HP. NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation. Eur J Med Chem. 2017 Sep 21. pii: S0223-5234(17)30735-3. doi: 10.1016/j.ejmech.2017.09.021. [Epub ahead of print]
Bertoune M, Nickl B, Krieger T, Wohlers L, Bonaterra GA, Dietzschold B, Weihe E, Bette M. The phenotype of the RABV glycoprotein determines cellular and global virus load in the brain and is decisive for the pace of the disease. Virology. 2017 Aug 22;511:82-94. doi: 10.1016/j.virol.2017.08.019.
Hildebrandt W, Schwarzbach H, Pardun A, Hannemann L, Bogs B, König AM, Mahnken AH, Hildebrandt O, Koehler U, Kinscherf R (2017). Age-related differences in skeletal muscle microvascular response to exercise as detected by contrast-enhanced ultrasound (CEUS). PLoS One. 2017 Mar 8;12(3):e0172771. doi: 10.1371/journal.pone.0172771.J
Schwarz A, Bonaterra GA, Schwarzbach H, Kinscherf R (2017). Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation. Biomed Sci. 2017 Feb 7;24(1):12. doi: 10.1186/s12929-017-0320-5.
Ringer C, Tune S, Bertoune MA, Schwarzbach H, Tsujikawa K, Weihe E, Schütz B. Disruption of calcitonin gene-related peptide signaling accelerates muscle denervation and dampens cytotoxic neuroinflammation in SOD1 mutant mice. Cell Mol Life Sci. 2017 Jan;74(2):339-358. doi: 10.1007/s00018-016-2337-4. Epub 2016 Aug 23.
Bonaterra GA, Kelber O, Weiser W, Kinscherf R (2017). Anti-inflammatory effects of Phytodolor® (STW 1) and components (poplar, ash and goldenrod) in human monocytes/macrophages. Front Pharmacol (in revision).
Rodepeter FR, Wiegand S, Lüers HG, Bonaterra GA, Lowe AW, Bette M, Jacob R, Mandic R. Indication for differential sorting of the rat v-SNARE splice isoforms VAMP-1a and -1b. Biochem Cell Biol. 2017 Mar 17. doi: 10.1139/bcb-2016-0184.
Bonaterra GA, Driscoll D, Schwarzbach H, Kinscherf R. Krill Oil-In-Water Emulsion Protects against Lipopolysaccharide-Induced Proinflammatory Activation of Macrophages In Vitro. Mar Drugs. 2017 Mar 15;15(3). pii: E74. doi: 10.3390/md15030074.
Atherton PJ, Kumar V, Selby AL, Rankin D, Hildebrandt W, Phillips BE, Williams JP, Hiscock N, Smith K. Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men. Clin Nutr. 2017 Jun;36(3):888-895. doi: 10.1016/j.clnu.2016.04.025. Epub 2016 Apr 30.
Bette M, Springmann V, Rossmann A, Weihe E, Schütz B. Evidence for the absence of visceral pain in C57BL6/N mice subjected to therapeutically relevant O3/O2-pneumoperitoneum. Lab Anim 2017;51(1):17-23 doi: 10.1177/0023677216636832
Ringer C, Weihe E, Schütz B. SOD1G93A Mutant Mice Develop a Neuroinflammation-Independent Dendropathy in Excitatory Neuronal Subsets of the Olfactory Bulb and Retina. J Neuropathol Exp Neurol 2017;76(9):769-78 doi: 10.1093/jnen/nlx057
2016
Oezel L, Then H, Jung AL, Jabori S, Bonaterra G,Wissniowski TT, Önel SF, Ocker M, Thieme K, Kinscherf R, Di Fazio P (2016). Fibromyalgia syndome: metabolic and autophagic processes in intermittent cold stress mice. Pharma Res Per, 000(000), 2016, e00248. doi: 10.1002/prp 2.248
Villa-de la Torre F, Kinscherf R, Bonaterra G, Arana-Argaez VE, Méndez-González M, Cáceres-Farfán M, Borges-Argáez R. Anti-inflammatory and immunomodulatory effects of Critonia aromatisans leaves: Downregulation of pro-inflammatory cytokines. J Ethnopharmacol. 2016 Jun 6;190:174-182. doi: 10.1016/j.jep.2016.06.006. [Epub ahead of print]
Bonaterra GA, Then H, Oezel L, Schwarzbach H, Ocker M, Thieme K, Di Fazio P, Kinscherf R (2016).Morphological Alterations in Gastrocnemius and Soleus Muscles in Male and Female Mice in a Fibromyalgia Model. PLoS One 17;11(3):e0151116.
Knies C, Hammerbacher K, Bonaterra GA, Kinscherf R, Rosemeyer H (2016).Novel Nucleolipids of Pyrimidine β-D-Ribonucleosides: Combinatorial Synthesis, Spectroscopic Characterization, and Cytostatic/Cytotoxic Activities. Chemistry & Biodiversity 13(2):160-80.
Knies C, Hammerbacher K, Bonaterra GA, Kinscherf R, Rosemeyer H (2016).Nucleolipids of Canonical Purine ß-d-Ribo-Nucleosides: Synthesis and Cytostatic/Cytotoxic Activities Toward Human and Rat Glioblastoma Cells. ChemistryOpen 5 (2):129-141.
Hildebrandt W, Sauer R, Koehler U, Bärtsch P, Kinscherf R (2016). Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes. BMC Pulm Med. 2016 Nov 24; 16(1):159.
2015
Knies C, Bonaterra G, Hammerbacher K, Cordes A, Kinscherf R, Rosemeyer H (2015). Ameliorated or Acquired Cytostatic/Cytotoxic Properties of Nucleosides by Lipophilization. Chemistry & Biodiversity 12(12): 1902–1944.
Sohrabi K, Scholtes M, Mursina L, Weissflog A, Hildebrandt W, Hildebrandt O, Gross V, Koehler U (2015). Determination of Hypercapnic Ventilatory Response in COPD Patients. Pneumologie 69(11):662-6.
Hildebrandt W, Sauer R, Bonaterra G, Dugi KA, Edler L, Kinscherf R (2015). Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status. Am J Clin Nutr.102(5):1014-24.
Reljic D, Jost J, Dickau K, Kinscherf R, Bonaterra G, Friedmann-Bette B (2015). Effects of pre-competitional rapid weight loss on nutrition, vitamin status and oxidative stress in elite boxers. J Sports Sci. 33(5): 437-48.
Kunz P, Fellenberg J, Moskovszky L, Sápi Z, Krenacs T, Machado I, Poeschl J,Lehner B, Szendrõi M, Ruef P, Bohlmann M, Bosch AL, Ewerbeck V, Kinscherf R, Fritzsching B (2015). Improved Survival in Osteosarcoma Patients with A typical Low Vascularization. Ann Surg Oncol. 22(2):4289-301.
Fritzsching B, Fellenberg J, Moskovszky L, Sápi Z, Krenacs T, Machado I, Poeschl J, Lehner B, Szendrõi M, Bosch AL, Bernd L, Csóka M, Mechtersheimer G, Ewerbeck V, Kinscherf R, Kunz P (2015). CD8+/FOXP3+-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study. Oncoimmunology 2;4(3):e990800.
Matschke LA, Bertoune M, Roeper J, Snutch TP, Oertel WH, Rinné S, Decher N. A concerted action of L- and T-type Ca(2+) channels regulates locus coeruleus pacemaking. Mol Cell Neurosci. 2015 Sep;68:293-302. doi: 10.1016/j.mcn.2015.08.012. Epub 2015 Aug 25.
Schütz B, Jurastow I, Bader S, Ringer C, von Engelhardt J, Chubanov V, Gudermann T, Diener M, Kummer W, Krasteva-Christ G, Weihe E. Chemical coding and chemosensory properties of cholinergic brush cells in the mouse gastrointestinal and biliary tract. Front Physiol 2015;6:87 doi: 10.3389/fphys.2015.00087
Schütz B, Schäfer MK, Gördes M, Eiden LE, Weihe E. Satb2-independent acquisition of the cholinergic sudomotor phenotype in rodents. Cell Mol Neurobiol 2015;35(2):205-16 doi: 10.1007/s10571-014-0113-2
Krasteva-Christ G, Soultanova A, Schütz B, Papadakis T, Weiss C, Deckmann K, Rafiq A, Chubanov V, Gudermann T, Voigt A, Meyerhof W, Weihe E, Kummer W. Identification of cholinergic chemosensory cells in mouse tracheal and laryngeal glandular ducts. Int Immunopharmacol 2015;29(1):158-65 doi: 10.1016/j.intimp.2015.05.028
2014
Bonaterra GA, Wakenhut F, Röthlein D, Wolf M, Bistrian BR, Driscoll D, Kinscherf R (2014). Cytoprotection by Omega-3 Fatty Acids as a Therapeutic Drug Vehicle When Combined With Nephrotoxic Drugs in an Intravenous Emulsion: Effects on Intraglomerular Mesangial Cells. Toxicol Reports 1: 843-857.
Weber N, Vieweg L, Henze F, Oprisoreanu AM, Solinski HJ, Breit A, Fecher-Trost C, Schalkowsky P, Wilhelm B, Wennemuth G, Schoch S, Gudermann T, Boekhoff I. RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction. J Mol Cell Biol. 2014 Oct;6(5):434-7.
Rossmann A, Mandic R, Heinis J, Hoeffken H, Kuessner O, Kinscherf R, Weihe E, Bette M (2014). Intraperitoneal oxidative stress in rabbits with papillomavirus-associated head and neck cancer induces tumoricidal immune response that is adoptively transferable. Clin Cancer Res. 20(16):4289-301.
Kunz P, Fellenberg J, Moskovszky L, Sápi Z, Krenacs T, Poeschl J, Lehner B, Szendrõi M, Ewerbeck V, Kinscherf R, Fritzsching B (2014). Osteosarcoma microenvironment: whole-side imaging and optimized antigen detection overcome majoer limitations in immunohistochemical quantification. PLoS One. 9(3):e90727.
Farhat A, Malecki E, Bonaterra GA, Röthlein D, Wolf M, Schmitt J, Rosemeyer H, Kinscherf R (2014). Cytostatic/Cytotoxic effects of 5-flourouridine nucleolipids on colon, hepatocellular and renal carcinoma cells: in vitro identification of a potential cytotoxic multi-anticancer drug.Chem Biodivers. 11(3):469-82.
Stern-Straeter J, Bonaterra GA, Juritz S, Birk R, Goessler UR, Bieback K, Bugert P, Schultz J, Hörmann K, Kinscherf R*, Faber A* (2014). Evaluation of the effects of different culture media on the myogenic differentiation potential of adipose tissue- or bone marrow human mesenchymal stem cells.Int J Mol Med.33(1):160-70. * geteilte Seniorautorenschaft
Deckmann K, Filipski K, Krasteva-Christ G, Fronius M, Althaus M, Rafiq A, Papadakis T, Renno L, Jurastow I, Wessels L, Schütz B, Weihe E, Chubanov V, Gudermann T, Klein J, Bschleipfer T, Kummer W. Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes. Proc Natl Acad Sci U S A 2014;111(22):8287-92 doi: 10.1073/pnas.1402436111
Panneck AR, Rafiq A, Schütz B, Soultanova A, Deckmann K, Chubanov V, Gudermann T, Weihe E, Krasteva-Christ G, Grau V, del Rey A, Kummer W. Cholinergic epithelial cell with chemosensory traits in murine thymic medulla. Cell Tissue Res 2014;358(3):737-48 doi: 10.1007/s00441-014-2002-x
2013
Malecki E, Farhat A, Bonaterra GA, Röthlein D, Wolf M, Schmitt J, Kinscherf R, Rosemeyer H (2013). Synthesis of 5-Fluorouridine Nucleolipid Derivatives and their cytostatic/cytotoxic activities on Human HT-29 Colon Carcinoma Cells. Chemistry & Biodiversity 10: 2235-2246.
Mey L, Hörmann M, Schleicher N, Reuter P, Dönges S, Kinscherf R, Gassmann M, Gerriets T, Al-Fakhri N (2013). Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis. Neurobiol Dis. 59:111-25.
Schwarz A, Wennemuth G, Post H, Brandenburger T, Aumüller G, Wilhelm B (2013). Vesicular transfer of membrane components to bovine epididymal spermatozoa. Cell Tissue Res. 353(3):549-61.
Bonaterra GA, Kelber O, Weiser D, Kinscherf R (2013). Mechanisms of the anti-proliferative and anti-inflammatory effects of the herbal fixed combination STW 5 (Iberogast®) on colon adenocarcinoma (HT29) cells in vitro. Phytomedicine. 2013 Jun 15;20(8-9):691-8. doi: 10.1016/j.phymed.2013.02.011 . Epub 2013 Mar 25.
Schober A, Parlato R, Huber K, Kinscherf R, Hartleben B, Huber TB, Schütz G, Unsicker K (2013). Cell loss and autophagy in the extra-adrenal chromaffin organ of zuckerkandl are regulated by gluccocorticoid signalling. J Neuroendocrinol 25 (1): 34-47.
Fuchs A, Kutterer S, Mühling T, Duda J, Schütz B, Liss B, Keller BU, Roeper J. Selective mitochondrial Ca2+ uptake deficit in disease endstage vulnerable motoneurons of the SOD1G93A mouse model of amyotrophic lateral sclerosis. J Physiol 2013;591(10):2723-45 doi: 10.1113/jphysiol.2012.247981
Ringer C, Büning LS, Schafer MK, Eiden LE, Weihe E, Schütz B. PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 2013;54C:32-42 doi:10.1016/j.nbd.2013.02.010
2012
Bonaterra GA, Zügel S, Thogersen J, Walther SA, Haberkorn U, Strelau J, Kinscherf R (2012).Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury. J Am Heart Assoc 1 (6). Epub 2012 Dec 19.
Streitner I, Goldhofer M, Cho S, Kinscherf R, Thielecke H, Borggrefe M, Süselbeck T, Streitner F (2012). Cellular imaging of human atherosclerotic lesions by intravascular electric impendance spectroscopy.PLoS One 7(4):e35405. Epub 2012 Apr 11.
Aumüller G, Doll A, WennemuthG, Dizeyi N, Abrahamsson PA, Wilhelm B (2012). Regional distribution of neuroendocrine cells in the urogenital duct system of the male rat. The Prostate 72: 326-337.
Rüschoff J*, Brandenburger, T*, Strehler,EE, Filoteo AG, Heinmöller E, Aumüller G, Wilhelm B (2012). Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis. Cancer Invest 30(4):251-7. (*beide Autoren teilen sich die Erstautorenschaft.)
Friedmann-Bette B, Schwartz FR, Eckhardt H, Billeter R, Bonaterra G, Kinscherf R (2012). Similar changes of gene expression in human skeletal muscle after resistance exercise and multiple fine needle biopsies.J Appl Physiol. 112(2): 289-95.
Phillips B, Williams J, Atherton PJ, Smith K, Hildebrandt W, Rankin D, Greenhaff PL, Macdonald IA, Rennie M (2012). Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise.J Appl Physiol. 112(3): 347-53.
Ringer C, Weihe E, Schütz B. Calcitonin gene-related peptide expression levels predict motor neuron vulnerability in the superoxide dismutase 1-G93A mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 2012;45(1):547-54 doi:10.1016/j.nbd.2011.09.011
Krasteva G, Hartmann P, Papadakis T, Bodenbenner M, Wessels L, Weihe E, Schütz B, Langheinrich AC, Chubanov V, Gudermann T, Ibanez-Tallon I, Kummer W. Cholinergic chemosensory cells in the auditory tube. Histochem Cell Biol 2012;137(4):483-97 doi: 10.1007/s00418-012-0911-x
2011
Katryniok C, Bonaterra GA, Traut U, Hollender R, Weiser D, Kelber O, Kinscherf R. Influence of STW 11, a fixed combination medicinal product on cytokine production of human macrophages. Basic & Clinical & Pharmacology & Toxicology (in press).
Brandenburger T, Strehler EE, Filoteo AG, Caride AJ, Aumüller G, Post H, Schwarz A, Wilhelm B (2011). Switch of PMCA4 splice variants in bovine epididymis results in altered isoform expression during functional sperm maturation. J Biol Chem 286(10): 7938-46.
Stern-Straeter J, Bonaterra GA, Kassner SS, Faber A, Sauter A, Schulz JD, Hörmann K, Kinscherf R*, Goessler UR* (2011). Impact of static magnetic fields on human myoblast cell cultures. Int J Mol Med. 28(6): 907-17. * geteilte Seniorautorenschaft
Stern-Straeter J, Bonaterra GA, Kassner SS, Zügel S, Hörmann K, Kinscherf R*, Goessler UR* (2011). Characterization of a human myoblast differentiation for tissue-engineering purposes by quantitative gene expression analysis.J Tissue Eng Regen Med 5(8): e197-206. * geteilte Seniorautorenschaft
Kassner SS, Schöttler S, Bonaterra GA, Stern-Sträter J, Sommer U, Hormann K, Kinscherf R*, Gössler UR* (2011). Proinflammatory and proadhesive activation of lymphocytes and macrophages in sudden sensorineural hearing loss. Audiol Neurootol 16(4): 254-62. * geteilte Seniorautorenschaft
Krasteva G, Canning B, Hartmann P, Veres T, Papadakis T, Mühlfeld C, Schliecker K, Tallini Y, Braun A, Hackstein H, Baal N, Weihe E, Schütz B, Kotlikoff M, Ibanez-Tallon I, Kummer W. Cholinergic chemosensory cells in the trachea regulate breathing. Proc Natl Acad Sci U S A 2011;108(23):9478-83 doi: 10.1073/pnas.1019418108
2010
Stern-Straeter J, Bonaterra GA, Zügel S, Kassner SS, Hörmann K, Kinscherf R, Goessler UR (2010). Evalution of valid reference genes during stimulation with static magnetic fields in human myoblast cultures. Mol Med Report 3(2): 237-43.
Bonaterra GA, Zügel S, Hildebrandt W, Kelber O, Weiser D, Metz J, Kinscherf R. Pro-apoptotic and anti-proliferative mechanisms of STW 5. Basic & Clinical Pharmacology & Toxicology (in press).
Bonaterra GA, Kelber O, Weiser D, Metz J, Kinscherf R (2010). In vitro anti-proliferative effects of the willow bark extract STW 33-I. Arzneimittelforschung 60(6): 330-335.
Bonaterra GA, Heinrich EU, Kelber O, Weiser D, Metz J, Kinscherf R (2010). Anti-inflammatory effects of the willow bark extract STW 33-I (Proactiv ((R))) in LPS-activated human monocytes and differentiated macrophages. Phytomedcine 17(14): 1106-13.
Kaiser E, Schoenknecht P, Kassner S, Hildebrandt W, Kinscherf R, Schroeder J (2010). Cerebrospinal fluid concentrations of functionally important amino acids and metabolic compounds in patients with mild cognitive impairment and Alzheimer´s desease. Neurodegener Dis 7(4): 251-259.
Bonaterra GA, Zügel S, Kinscherf R (2010). Novel systemic cardiovascular disease biomarkers. Curr Mol Med 10(2): 180-205.
Riedmüller K, Metz S, Bonaterra GA, Kelber O, Weiser D, Metz J, Kinscherf R (2010). Cholesterol diet and effect of long-term wethdrawal on plaque development and composition in the thoracic aorta of New Zealand White rabbits. Atherosclerosis 210(2): 407-13.
Friedmann-Bette B, Bauer T, Kinscherf R, Vorwald S, Klute K, Bischoff D, Müller H, Weber MA, Metz J, Kauczor HU, Bärtsch P, Belleter R (2010). Effects of strenght training with eccentric overload on muscle adaption in male athletes. Eur J Appl Physiol 108(4): 821-36.
Landré JB, Blaess MF, Kohl M, Schlicksbier T, Ruryk A, Kinscherf R, Claus RA, Hermetter A, Keller M, Bauer M, Deigner HP (2010). Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50fM. Anal Biochem 397(1): 60-6.
Weber MA, Hildebrandt W, Schröder L, Kinscherf R, Krix M, Bachert P, Delorme S, Essig M, Kauczor HU, Krakowski-Roosen H (2010). Concentric resistance training increases muscle strength without affecting microcirculation. Eur J Radiol 73(3): 614-21
Post H, Schwarz A, Brandenburger T, Aumüller G, Wilhelm B (2010). Arrangement of PMCA4 in bovine sperm membrane fractions. Int J Androl 33(6): 775-83.
Fuchs A, Ringer C, Bilkei-Gorzo A, Weihe E, Roeper J, Schütz B. Downregulation of the potassium chloride cotransporter KCC2 in vulnerable motoneurons in the SOD1-G93A mouse model of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2010;69(10):1057-70 doi:10.1097/NEN.0b013e3181f4dcef
2009
Barnes BB, Chang-Claude J, Flesch-Janys D, Kinscherf R, Schmidt M, Slanger T, Bonaterra G, Steindorf K (2009). Cancer risk factors associated with insulin-like growth factor (IGF)-I and IGF-binding protein-3 levels in healthy women: effect modification by menopausal status. Cancer Causes Control 20(10): 1985-96.
Stern-Straeter J, Bonaterra GA, Hörmann K, Kinscherf R, Goessler UR (2009). Identification of valid reference genes during the differentiation of human myoblasts. BMC Mol Biol 10: 66.
Streitner I, Goldhofer M, Cho S, Thielecke H, Kinscherf R, Streitner F, Metz J, Haase KK, Borggrefe M, Süselbeck T (2009). Electric impedance spectroscopy of human atherosclerotic lesions. Atherosclerosis 206(2): 464-68.
Nef HM, Möllmann H, Joseph A, Troidl C, Voss S, Rauch M, Kinscherf R, Vogt A,Weber M, Hamm CW, Elsässer A (2009). Reduction of neointimal hyperplasia in porcine coronary arteries by 2-deoxy-D-glucose. Clin Res Cardiol 98(6): 355-61.
Kassner SS, Kollmar R, Bonaterra GA, Hildebrandt W, Schwab S, Kinscherf R (2009). The early immunological response to acute ischemic stroke: differential gene expression in Subpopulations of mononuclear cells. Neuroscience 160(2): 394-401.
Noor F, Kinscherf R, Bonaterra GA, Walczak S, Wölfl S, Metzler-Nolte N (2009). Enhanced Cellular Uptake and Cytotoxicity Studies of Organometallic Bioconjugates of the NLSPeptide in Hep G2 Cells. Chembiochem 10(3): 493-502.
Weber MA, Krakowski-Roosen H, Schroder L, Kinscherf R, Krix M, Kopp-Schneider A, Essig M , Bachert P, Kauczor HU, Hildebrandt W (2009). Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia. Acta Oncol 48(1): 116-24.
Enderlin M, Kleinmann EV, Struyf S, Buracchi C, Vecchi A, Kinscherf R, Kiessling F, Paschek S, Sozzani S, Rommelaere J, Cornelis JJ, van Damme J, Dinsart C (2009). TNF-α and the IFN-g -inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act insynergy to induce antitumor effects in mouse glioblastoma. Cancer Gene Therapy 16(2): 149-60.
Kumar V, Selby A, Rankin D, Patel R, Atherton P, Hildebrandt W, Williams J, Smith K, Seynnes O, Hiscock N, Rennie MJ (2009). Age-related differences in the dose-response relationship of muscle protein synthesis to resitance exercise in young and old men. J Physiol 587(Pt 1): 211-17.
Preuss MA, Faber ML, Tan GS, Bette M, Dietzschold B, Weihe E, Schnell MJ. Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers. PLoS Pathog. 2009 Jun;5(6):e1000485. doi:10.1371/journal.ppat.1000485. Epub 2009 Jun 19.
Ringer C, Weihe E, Schütz B. Pre-symptomatic alterations in subcellular betaCGRP distribution in motor neurons precede astrogliosis in ALS mice. Neurobiol Dis 2009;35(2):286-95 doi: S0969-9961(09)00109-0 10.1016/j.nbd.2009.05.011
2008
Ackermann F, Zitranski N, Heydecke D, Wilhelm B, Gudermann T, Boekhoff I (2008). The Multi-PDZ domain protein MUPP1 as a lipid raft-associated scaffolding protein controlling the acrosome reaction in mammalian spermatozoa. J Cell Physiol 214(3): 757-68.
Blessing E, Preusch M, Kranzhöfer R, Kinscherf R, Marx N, Rosenfeld ME, Isermann B, Weber CM, Kreuzer J, Gräfe J, Katus HA, Bea F (2008). Anti-atherosclerotic properties of telmisartan in advanced atherosclerotic lesions in apolipoprotein E deficient mice. Atherosclerosis 199(2): 295-303.
Kassner SS, Bonaterra GA, Kaiser E, Hildebrandt W, Metz J, Schröder J, Kinscherf R (2008). Novel systemic markers for patients with Alzheimer disease? – A pilot study. Curr Alz Res 5(4): 358-366.
Post H*, Gutberlet J*, Wiche R, Aumüller G, Wilhelm B (2008). The localization of PMCA1b in epithelial cells and aposomes of the rat coagulating gland is influenced by androgens. The Prostate 68(10): 1076 *beide Autoren teilen sich die Erstautorenschaft.
Wilhelm B, Brandenburger T, Post H, Aumüller G (2008). Expression and localization of PMCA4 in rat testis and epididymis. Histochem Cell Biol 129(3): 331-43.
Weihe E, Bette M, Preuss MA, Faber M, Schäfer MK, Rehnelt J, Schnell MJ, Dietzschold B. Role of virus-induced neuropeptides in the brain in the pathogenesis of rabies. Dev Biol (Basel). 2008;131:73-81.
Schütz B, von Engelhardt J, Gördes M, Schäfer MK-H, Eiden LE, Monyer H, Weihe E. Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse. Neuroscience 2008;156(2):310-8 doi:10.1016/j.neuroscience.2008.06.074
2007
Bonaterra GA, Hildebrandt W, Bodens A, Sauer R, Dugi KA, Deigner HP, Turcanu D, Heinle H, Dröge W, Metz J, Kinscherf R (2007). Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males. J Mol Med 85(2): 181-90.
Fehr J, Meyer D, Widmayer P, Borth HC, Ackermann F, Wilhelm B, Gudermann T, Boekhoff I (2007). Expression of the G-protein alpha-subunit gustducin in mammalian spermatozoa. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193(1): 21-34.
Haberkorn U, Hoffend J, Schmidt K, Altmann A, Bonaterra GA, Dimitrakopoulou-Strauss A, Strauss LG, Eisenhut M, Kinscherf R (2007). Changes in glucose metabolism and gene expression after transfer of anti-angiogenic genes in rat hepatoma. Eur J Nucl Med Mol Imaging 34(12): 2011.
Holm E, Hildebrandt W, Kinscherf R, Dröge W (2007). Low absorptive net protein degradation in male cancer patients: Lack of sensitivity to regulatory amino acids? OncologyReports 17: 695-700.
Schmitt TL, Martignoni ME, Bachmann J, Fechtner K, Friess H, Kinscherf R, Hildebrandt W (2007). Activity of the Akt-dependent anabolic and catabolic pathways in muscle and liver samples in cancer-related cachexia. J Mol Med 85(6): 647-54.
Triphan J, Aumüller G, Brandenburger T, Wilhelm B (2007). Localization and regulation of plasma membrane Ca2+-ATPase in bovine spermatozoa. Eur J Cell Biol 86(5): 265-273.
Weber MA, Krakowski-Roosen H, Hildebrandt W, Schröder L, Ionescu I, Krix M, Kinscherf R, Bachert P, Kauczor HU, Essig M (2007). Assessment of Metabolism and Microcirculation of Healthy Skeletal Muscles by Functional Magnetic Resonance and Ultrasound Techniques. J Neuroimaging 17(4): 323-31.
Weber MA, Kinscherf R, Krakowski-Roosen H, Aulmann M, Renk H, Künkele A, Edler L, Kauczor HU, Hildebrandt W (2007) Myoglobin plasma level related to muscle mass and fibercomposition - a clinical marker of muscle wasting ? J Mol Med 85(8): 887-96.
Wolf M, Hull WE, Mier W, Heiland S, Bauder-Wust U, Kinscherf R, Haberkorn U, Eisenhut M (2007). Polyamine-Substituted Gadolinium Chelates: A New Class of Intracellular Contrast Agents for Magnetic Resonance Imaging of Tumors. J Med Chem 50(1): 139-148.
Smith JA, Nunnari G, Preuss M, Pomerantz RJ, Daniel R. Pentoxifylline suppresses transduction by HIV-1-based vectors. Intervirology. 2007;50(5):377-86. Epub 2007 Oct 15.
Faber M, Faber ML, Li J, Preuss MA, Schnell MJ, Dietzschold B. Dominance of a nonpathogenic glycoprotein gene over a pathogenic glycoprotein gene in rabies virus. J Virol. 2007 Jul;81(13):7041-7. Epub 2007 Apr 25.
Tan GS, Preuss MA, Williams JC, Schnell MJ. The dynein light chain 8 binding motif of rabies virus phosphoprotein promotes efficient viral transcription. Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7229-34. Epub 2007 Apr 16.
2006
Heydecke D, Meyer D, Ackermann F, Wilhelm B, Gudermann T, Boekhoff I (2006). The multi PDZ domain protein MUPP1 as a putative scaffolding protein for organizing signaling complexes in the acrosome of mammalian spermatozoa. J Androl 27(3): 390-404.
Kreusser M, Haass M, Buss SJ, Hardt SE, Gerber SH, Kinscherf R, Katus HA, Backs J (2006). Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts. Hypertension 47(2): 209-15.
Kristen AV, Kreusser M, Lehmann L, Kinscherf R, Katus HA, Haass M, Backs J (2006). Preserved Norepinephrine Reuptake but Reduced Sympathetic Nerve Endings inHypertrophic Volume-Overloaded Rat Hearts. J Cardiac Failure 12(7): 577-83.
Kunz P, Hoffend J, Altmann A, Dimitrakopoulou-Strauss A, Koczan D, Eisenhut M, Bonaterra GA, Dengler TJ, Haberkorn U*, Kinscherf R* (2006). Angiopoietin-2-Over-expression in orris Hepatoma Results in Increased Tumor Perfusion and Induction of Critical Angiogenesis-Promoting Genes. J Nucl Med 47(9): 1515-1524* beide Verfasser teilen sich die Seniorautorenschaft.
Schmidt K, Hoffend J, Altmann A, Kiessling F, Strauss LG, Koczan D, Mier W, Eisenhut M, Kinscherf R*, Haberkorn U* (2006). Troponin I Overexpression Inhibits Tumor Growth, Perfusion and Vascularization of Morris Hepatoma. J Nucl Med 47(9): 1506-1514 *beide Verfasser teilen sich die Seniorautorenschaft.
Schmidt K, Hoffend J, Altmann A, Strauss LG, Engelhardt B, Koczan D, Peter J, Dengler TJ, Mier W, Eisenhut M, Haberkorn U, Kinscherf R (2006). Angiostatin Overexpression in Morris Hepatoma Results in Decreased Tumor Growth but Increased Perfusion and Vascularization. J Nucl Med 47(3): 543-551.
Weber MA, Krakowski-Roosen H, Delorme S, Renk H, Krix M, Millies J, Kinscherf R, Künkele A, Kauczor HU, Hildebrandt W (2006). Relation of skeletal muscle perfusion measured by contrast-enhanced ultrasound to histological microvascular density. J Ultrasound Med 25(5): 583-91.
Dröge W,Kinscherf R, Hildebrandt W, Schmitt T (2006). The deficit in low molecular weights thiols as a target for antiageing therapy. Current Drug Targets 7(11): 1505-12.
Duarte CR, Schütz B, Zimmer A. Incongruent pattern of neurokinin B expression in rat and mouse brains. Cell Tissue Res 2006;323(1):43-51 doi: 10.1007/s00441-005-0027-x
Weihe E, Depboylu C, Schütz B, Schäfer MK, Eiden LE. Three types of tyrosine hydroxylase-positive CNS neurons distinguished by dopa decarboxylase and VMAT2 co-expression. Cell Mol Neurobiol 2006;26(4-6):659-78 doi: 10.1007/s10571-006-9053-9
2005
Bonaterra GA, Hildebrandt W, Bodens A, Sauer R, Dugi KA, Schlittenhardt D, Deigner HP, Dröge W, Metz J, Kinscherf R (2005). Increased Cyclooxygenase-2 Expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects. Free Radic Biol Med 38(2): 235-42.
Claus RA, Wuestholz A, Mueller S, Riedel NH, Kinscherf R, Deigner HP (2005). Synthesis and anti-apoptotic activity of novel analogue of the neutral Sphingomyelin-ase inhibitor scyphostatin. ChemBioChem 6(4): 726-37.
Claus RA, Bunck AC, Brunkhorst FM, Bockmeyer CL, Meisner M, Lösche W, Kinscherf R, Deigner HP (2005). Role of Increased Sphingomyelinase Activity in Apoptosis and Organ Failure of Patients with Sepsis. FASEB J 2005 19(12): 1719.
Hoffend J, Mier W, Schuhmacher J, Schmidt K, Dimitrakopoulou-Strauss A, Strauss LG, Eisenhut M, Kinscherf R, Haberkorn U (2005). Gallium-68-DOTA-Albumin as a PETBlood-Pool Marker: Experimental Evaluation in vivo. Nucl Med Biol 32: 287-292.
Noor F, Wüstholz A, Kinscherf R, Metzler-Nolte N (2005). Enhanced cellular uptake anddirected nuclear delivery of a metallocene peptide bioconjugate. Angew Chem 44(16): 2429-32.
Schlittenhardt D, Schmiedt W, Bonaterra GA, Metz J, Kinscherf R (2005). Colocalization ofoxidized low-density lipoprotein, caspase-3, cyclooxygenase-2, and macrophage migration inhibitory factor in arteriosclerotic human carotid arteries. Cell Tissue Res 31: 1-11.
Schmidt K, Hoffend J, Altmann A, Strauss LG, Dimitrakopoulou-Strauss A, Engelhardt B, Koczan D, Peter J, Vorwald S, Eskerski H, Eisenhut M, Metz J, Kinscherf R, Haberkorn U (2005). Transfer of the gene for the soluble receptor for the vascular endothelial growth factor inhibits tumor growth of Morris hepatoma independent from perfusion. Clin Cancer Res 11(6): 2132-40.
Zitzmann S, Mier W, Schad A, Kinscherf R, Askoxylakis V, Krämer S, Altmann A, Eisenhut M, Haberkorn U. (2005). A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy. Clin Cancer Res 11: 139-146.
Faber M, Bette M, Preuss MA, Pulmanausahakul R, Rehnelt J, Schnell MJ, Dietzschold B, Weihe E. Overexpression of tumor necrosis factor alpha by a recombinant rabies virus attenuates replication in neurons and prevents lethal infecgtion in mice. J Virol. 2005 Dec; 79(24):15405-16.
Schütz B. Imbalanced excitatory to inhibitory synaptic input precedes motor neuron degeneration in an animal model of amyotrophic lateral sclerosis. Neurobiol Dis 2005;20(1):131-40 doi: S0969-9961(05)00068-9 10.1016/j.nbd.2005.02.006
Schütz B, Reimann J, Dumitrescu-Ozimek L, Kappes-Horn K, Landreth G, Schürmann B, Zimmer A, Heneka MT. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J Neurosci 2005;25(34):7805-12 doi:10.1523/JNEUROSCI.2038-05.2005
Rácz I, Schütz B, Abo-Salem OM, Zimmer A. Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice. Neuroreport 2005;16(18):2025-8 doi:00001756-200512190-00011
Weihe E, Schütz B, Hartschuh W, Anlauf M, Schäfer MK, Eiden LE. Coexpression of cholinergic and noradrenergic phenotypes in human and nonhuman autonomic nervous system. J Comp Neurol 2005;492(3):370-9 doi:10.1002/cne.20745
2004
Albrecht M, Doroszewicz J, Gillen S, Gomes I, Wilhelm B, Stief T, Aumüller G (2004). Proliferation of prostate cancer cells and activity of neutral endopeptidase is regulated by bombesin and IL-1ß with IL-1ß acting as a modulator of cellular differentiation. The Prostate 58: 82-94.
Friedmann B, Kinscherf R, Borisch S, Kucera K, Müller H, Richter G, Bärtsch P, Billeter R (2004). Increased expression of fast myosin heavy chain mRNA in human skeletal muscle after computer-guided strength training with eccentric overload. Acta Physiol Scand 182: 77-88.
Haberkorn U, Beuter P, Kübler W, Eskerski H, Eisenhut M, Kinscherf R, Zitzmann S, Strauss LG, Dimitrakopoulou-Strauss A, Altmann A (2004). Iodide kinetics and dosimetry in vivo after transfer of the human sodium iodide symporter gene in rat thyroid carcinoma cells. J Nucl Med 45: 827-833.
Hildebrandt W, Hahmann A, Krakowski-Roosen H, Kinscherf R, Dugi K, Sauer R, Lacher S Nöbel N, Bodens A, Bellou V, Edler L, Bärtsch P, Nawroth P, Dröge W (2004). Effect of thiol antioxidant on body fat and insulin reactivity. J Mol Med 82: 336-344.
Sánchez-Luengo S, Aumüller G, Albrecht M, Sen P, Röhm KH, Wilhelm B (2004). Interaction of PDC-109, the major secretory protein from bull seminal vesicles, with bovine sperm membrane Ca2+-ATPase. J Androl 25: 234-244.
Schlittenhardt D, Schober A, Strelau J, Traut U, Schmiedt W, Unsicker K, Metz J, Kinscherf R (2004). Involvement of Growth Differentiation Factor-15/ Macrophage Inhibitory Cytokine 1 (GDF-15/MIC-1) in oxLDL-induced Apoptosis of Human Macrophages in vitro and in Arteriosclerotic Lesions. Cell Tissue Res 318(2): 325-334.
Song J, Aumüller G, Xiao F, Wilhelm B, Albrecht M (2004). Cell specific expression of CD10/neutral endopeptidase 24.11 gene in human prostatic tissue and cells. The Prostate 58: 394-405.
Eiden LE, Schäfer MK, Weihe E, Schütz B. The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine. Pflugers Arch 2004;447(5):636-40 doi: 10.1007/s00424-003-1100-5
Schütz B, Mauer D, Salmon AM, Changeux JP, Zimmer A. Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. J Comp Neurol 2004;476(1):32-43 doi: 10.1002/cne.20211
Harvey RJ, Depner U, Wässle H, Ahmadi S, Heindl C, Reinold H, Smart TG, Harvey K, Schütz B, Abo-Salem OM, Zimmer A, Poisbeau P, Welzl H, Wolfer DP, Betz H, Zeilhofer HU, Müller U. GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science 2004;304(5672):884-7 doi: 304/5672/884
2003
Albrecht M, Mittler A, Wilhelm B, Lundwall A, Lilja H, Aumüller G, Bjartell A (2003). Expression and immunolocalisation of neutral endopeptidase in prostate cancer. Europ Urol 44: 415-422.
Friedmann B, Kinscherf R, Borisch S, Richter G, Bärtsch P, Billeter R (2003). Effects of low resistance-high repetition strength training in hypoxia on muscle structure and gene expression. Pflügers Arch Eur J Physiol 446 (6): 742-51.
Haberkorn U, Kinscherf R, Kissel M, Kübler W, Mahmut M, Sieger S, Eisenhut M, Peschke P, Altmann A (2003). Transfer of the human sodium iodide symporter gene in rat prostate carcinoma cells. Gene Therapy 10 (9): 774-780.
Kinscherf R, Cafaltzis K, Röder F, Hildebrandt W, Deigner HP, Breitkreutz R, Feussner G, Kreuzer J, Werle E, Michel G, Metz J, Dröge W (2003). Decrease of HDL-cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox state in hyperlipi-demic subjects. Free Radic Biol Med 35(10): 1286-1292.
Kinscherf R, Kamencic H, Deigner HP, Metz J (2003). Long-term increas of macrophages, but not of dendritic cells in the myocardium of New Zealand White Rabbits due to hypercholesterolemia. Cells Tissue Organs 174 (4): 184-193.
Lysek N, Kinscherf R, Claus R, Lindel T (2003). L-5-Hydroxytryptophan: antioxidant and anti-apoptotic principle of the intertidal sponge Hymeniacidon heliophila. Z Naturforsch [C] 58(7-8): 568-72.
Wiche R, Seitz J, Wilhelm B (2003). Establishing of two in vitro models of epithelial cells from the apocrine secreting rat coagulating gland. Andrologia 35: 342-350.
Wilhelm B, Geyer H, Geyer R, Schwaeble W, Linder M, Linder D, Aumüller G, Seitz J (2003). Molecular comparison of apocrine released and cytoplasmic resident carbonic anhydrase II. Biochimie 85: 939-946.
Zugck C, Lossnitzer D, Backs J, Kristen A, Kinscherf R, Haass M (2003). Increased cardiac norepinephrine release in spontaneously hypertensive rats: role of presynaptic alpha-2a adrenoceptors. Hypertension 21: 1-7.
Schütz B, Damadzic R, Weihe E, Eiden LE. Identification of a region from the human cholinergic gene locus that targets expression of the vesicular acetylcholine transporter to a subset of neurons in the medial habenular nucleus in transgenic mice. J Neurochem 2003;87(5):1174-83 doi: 2095
2002
Albrecht M, Gillen S, Wilhelm B, Doroszewicz J, Aumüller G (2002). Expression, localization and activity of neutral endopeptidase in cultured cells of benign prostatic hyperplasia and prostate cancer. J Urolology 168: 336-342.
Hildebrandt W, Kinscherf R, Hauer K, Holm E, Dröge W (2002). Plasma cystine concentration and redox state in ageing and physical exercise. Mechanism Aging Dev 123 (9): 1269-1281.
Matsuba S, Suga Y, Ishidoh K, Hashimoto Y, Takamori K, Kominami E, Wilhelm B, Seitz J, Ogawa H (2002). Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells. J Dermatol Sci 30: 50-62.
Post H, Wiche R, Sen PC, Hoffbauer G, Albrecht M, Seitz J, Aumüller G, Wilhelm B (2002). Identification of a plasma membrane Ca2+-ATPase in epithelial cells and aposomes of the rat coagulating gland. The Prostate 52: 159-166.
Weiss C, Bierhaus A, Kinscherf R, Hack V, Luther T, Nawroth PP, Bärtsch P (2002).The tissue factor dependent pathway is not involved in exercise-induced activation of coagulation in PBMC. J Appl Physiol 92(1): 211-218.
Wilhelm B, Keppler C, Henkeler A, Schilli-Westermann M, Linder D, Aumüller G, Seitz J (2002). Identification and characterization of an IgG binding protein in the secretion of the rat coagulating gland. Biol Chem 383: 1959-1965.
Boldogköi Z, Schütz B, Sallach J, Zimmer A. P2X(3) receptor expression at early stage of mouse embryogenesis. Mech Dev 2002;118(1-2):255-60 doi: S0925477302002800
2001
Arenas MI, Royuela M, Fraile B, Paniagua R, Wilhelm B, Aumüller G (2001). Identification of N- and O-linked oligosaccharides in human seminal vesicles. J Androl 22: 79-87.
Becker R, Bauer A, Metz S, Kinscherf R, Senges JC, Schreiner KD, Voss F, Kuebler W, Schoels W (2001). Intercaval Block in Normal Canine Hearts: Role of the Crista Terminalis. Circulation 103(20): 2521-26.
Deigner HP, Claus R, Bonaterra GA, Gehrke C, Bibak N, Blaess M, Cantz M, Metz J, Kinscherf R (2001). Ceramide induces aSMase expression: Implications for oxLDL-induced apoptosis. FASEB J 15: 807-814.
Delorme S, Haberkorn U, Kinscherf R, Zuna I, Bahner ML, van Kaick G (2001). Changes of tumor vascularization during gene therapy: Monitoring with color Doppler US. Ultrasound Med Biol 27 (12): 1595-1603.
Eickhoff R, Wilhelm B, Renneberg H, Wennemuth G, Bacher M, Linder D, Bucala R, Seitz J, Meinhardt A (2001). Purification and characterization of macrophage migration inhibitory factor as a secretory protein from rat epididymis: evidences for alternative release and transfer to spermatozoa. Mol Med 7: 27-35.#
Haberkorn U, Altmann A, Kamencic H, Morr I, Traut U, Henze M, Jiang S, Metz J, Kinscherf R (2001). Glucose transport and apoptosis after gene therapy with HSV thymidine kinase. Eur J Nucl Med 28: 1690-1696.
Haberkorn U, Bellemann ME, Brix G, Kamencic H, Morr I, Traut U, Altmann A, Doll J, Blatter J, Kinscherf R (2001). Apoptosis and changes in glucose transport early after treatment of Morris hepatoma with gemcitabine. Eur J Nucl Med 28: 418-425.
Haberkorn U, Kinscherf R, Krammer PH, Mier W, Eisenhut, M (2001). Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-Methyl)-fluoromethyl Ketone. Nucl Med Biol 28: 793-798.
Metz S, Riedmüller K, Kinscherf R, Metz J (2001). Möglichkeiten der Regression bei der Arteriosklerose. Z Gerontol Geriat 34(6): 466-469.
Renneberg H, Albrecht M, Kurek R, Krause E, Lottspeich F, Aumüller G, Wilhelm B (2001). Identification and characterization of neutral endopeptidase (EC 24.11) from human prostasomes – localization in prostatic tissue and cell lines. The Prostate 46: 173-183.
Schober A, Böttner M, Strelau J, Kinscherf R, Bonaterra GA, Barth M, Schilling L, Fairlie D, Breit SN, Unsicker K (2001) Expression of growth differentiation factor-15/macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult and injured rat brain. J Comp Neurol 439 (1): 32-45.
Schütz B, Weihe E, Eiden LE. Independent patterns of transcription for the products of the rat cholinergic gene locus. Neuroscience 2001;104(3):633-42 doi: S0306-4522(01)00100-2
2000
Claus R, Kinscherf R, Gehrke C, Bonaterra GA, Basnet P, Metz J, Deigner HP (2000). Anti- apoptotic effects of Propolis extract and propol on human macrophages exposed to minimally modified LDL. Arzneimittel-Forsch 50: 373-379.
Kinscherf R, Metz J (2000). Die Bedeutung des oxidativen Stresses für Gefäßwandveränderungen. Deutsche Zeitschrift Sportmed 1: 6-10.
Schütz B, Chen L, Schäfer MK, Weihe E, Eiden LE. Somatomotor neuron-specific expression of the human cholinergic gene locus in transgenic mice. Neuroscience 2000;96(4):707-22 doi: S0306452299005874
1999
Deigner HP, Kinscherf R, Claus R, Fyrnys B, Blencowe C, Hermetter A (1999). Novel reversibel, irreversibel and fluorescent inhibitors of platelet-activating factor acetylhy-drolase as mechanistic probes. Atherosclerosis 144: 79-90.
Kinscherf R, Wagner M, Kamencic H, Bonaterra GA, Hou D, Schiele RA, Deigner HP, Metz J (1999). Characterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits. Atherosclerosis 144: 33-39.
Groos S, Wilhelm B, Renneberg H, Riva A, Reichelt R, Seitz J, Aumüller G (1999). Simultaneous apocrine and merocrine secretion in the rat coagulating gland. Cell Tissue Res 295: 495-504.
Wilhelm B, Meinhardt A, Renneberg H, Linder D, Gabius H-J, Aumüller G, Seitz J (1999). Serum albumin as potential carrier for the apocrine secretion of proteins in the rat coagulating gland. Eur J Cell Biol 78: 256-264.
1998
Schütz B, Schäfer MK, Eiden LE, Weihe E. Ontogeny of vesicular amine transporter expression in the rat: new perspectives on aminergic neuronal and neuroendocrine differentiation. Adv Pharmacol 1998;42:903-8
Weihe E, Schäfer MK-H, Schütz B, Anlauf M, Depboylu C, Brett C, Chen L, Eiden LE. From the cholinergic gene locus to the cholinergic neuron. J Physiol Paris 1998;92(5-6):385-8 doi: S0928-4257(99)80010-2
Schütz B, Schäfer MK, Eiden LE, Weihe E. VIP and NPY expression during differentiation of cholinergic and noradrenergic sympathetic neurons. Ann N Y Acad Sci 1998;865:537-41
Schütz B, Schäfer MK, Eiden LE, Weihe E. Vesicular amine transporter expression and isoform selection in developing brain, peripheral nervous system and gut. Brain Res Dev Brain Res 1998;106(1-2):181-204
Hack V, Breitkreutz R, Kinscherf R, Röhrer H, Bärtsch P, Taut F, Edler L, Dröge W (1998). The redox state as a correlate of senescence and wasting and as a target for therapeutic intervention. Blood 92: 59-67.
Kinscherf R, Claus R, Wagner M, Gehrke C, Kamencic H, Hou D, Chen M, Nauen O, Schmiedt W, Kovacs G, Pill J, Metz J, Deigner HP (1998). Apoptosis caused by Oxidized-LDL is manganese superoxide dismutase and p53-dependent. FASEB J 12: 461-467.
Kramer MF, Kinscherf R, Aidonidis I, Metz J (1998). Reorganisation of the terminalvascularisation after experimental myocardial infarction. Cell Tissue Res 291: 97-105.
Schmiedt W, Kinscherf R, Deigner HP, Kamencic H, Nauen O, Kilo J, Oelert H, Metz J, Bhakdi S (1998). Complement C6-deficiency protects against diet-induced atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol 18: 1790-1795.
Wilhelm B, Keppler C, Hoffbauer G, Lottspeich F, Linder D, Meinhardt A, Aumüller G, Seitz J (1998). Cytoplasmic carbonic anhydrase II of rat coagulating gland is secreted via the apocrine export mode. J Histochem Cytochem 46: 505-511.
1997
Schäfer MK, Schütz B, Weihe E, Eiden LE. Target-independent cholinergic differentiation in the rat sympathetic nervous system. Proc Natl Acad Sci U S A 1997;94(8):4149-54
Bidmon HJ, Overman E, Schleicher A, Kato K, Kinscherf R, Buchkremer-Ratzmann I, Witte OW, Zilles K (1997). Copper-zinc dismutase and isolectin B4 binding are markers for associative and transhemispheric diaschisis. Neurosci Lett 228: 163-166.
Hack V, Schmid D, Breitkreuz R, Stahl-Hennig C, Drings P, Kinscherf R, Taut F, Holm E, Dröge W (1997). Cystine levels, cystine flux and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence. FASEB J 11: 84-92.
Kinscherf R, Deigner HP, Usinger C, Pill J, Wagner M, Kamencic H, Hou D, Chen M, Schmiedt W, Schrader M, Kovacs G, Kato K, Metz J (1997). Induction of manganese superoxide dismutase by oxidized-LDL - Its Relevance in Atherosclerosis of humans and heritable hyperlipidemic rabbits. FASEB J 11: 1317-1328.
Kinscherf R, Kamencic H, Deigner HP, Pill J, Schmiedt W, Schrader M, Metz J (1997). Effect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits. J Leukocyte Biol 62: 719-725.
Kinscherf R, Claus R, Deigner HP, Nauen O, Gehrke C, Hermetter A, Rußwurm S, Daniel V, Hack V, Metz J (1997). Modified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophages. FEBS Lett 405: 55-59.
Kollum M, Kaiser S, Kinscherf R, Metz J, Kübler W, Hehrlein C (1997). Apoptosis after stent implantation compared with balloon angioplasty in rabbits. The role of macrophages. Arterioscler Thromb Vasc Biol 17: 2383-2388.
Aumüller G, Renneberg H, Schiemann PJ, Wilhelm B, Seitz J, Konrad L, Wennemuth G (1997). The role of apocrine released proteins in the post-testicular regulation of human sperm function. Adv Exp Med Biol 424: 193-219.
1996
Hack V, Stütz O, Kinscherf R, Schykowski M, Kellerer M, Holm E, Dröge W (1996). Elevated venous glutamate levels in (pre)catabolic conditions result at least partly from decreased glutamate transport activity. J Mol Med 74: 337 – 343.
Hack V, Groß A, Kinscherf R, Bockstette M, Fiers W, Berke G, Dröge W (1996). Abnormal glutathione and sulfate levels after interleukin-6 treatment and in tumor-induced cachexia. FASEB J 10: 1219–1226.
Hehrlein C, Stintz M, Kinscherf R, Schlösser K, Huttel E, Friedrich L, Fehsenfeld P, Kübler W (1996). Pure b-particle emitting stents inhibit neointima formation in rabbits. Circulation 93: 641-645.
Kinscherf R, Hack V, Fischbach T, Friedmann B, Weiss C, Edler L, Bärtsch P, Dröge W (1996). Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass (BCM) in healthy individuals - The effect of N-Acteyl-Cysteine. J Mol Med 74: 393-400.
1995
Dröge W, Kinscherf R, Mihm S, Galter D, Roth S, Gmünder H, Fischbach T, and M. Bockstette (1995). Thiols and the immune system.-The effect of N-acetyl-cysteine on the T cell system in human subjects. Methods Enzymol 251: 255–270.
Kinscherf R, Metz J, Wülfroth PM (1995). Etofibrate suppresses neointima formation of the ballooned common carotid artery of rats. Naunyn-Schmiedeberg's Arch Pharmacol 352: 424–428.
Weiss C, Kinscherf R, Roth S, Friedmann B, Fischbach T, Reus J, Dröge W, Bärtsch P (1995). Lymphocyte subpopulations and concentration of soluble CD8 and CD4 antigen after anaerobic training. Int J Sports Med 16 (2): 117–121.
1994
Schütz B, Niessing J. Cloning and structure of a chicken zinc finger cDNA: restricted expression in developing neural crest cells. Gene 1994;148(2):227-36
Dröge W, Eck HP, Mihm S, Roth S, Kinscherf R, Fischbach T (1994). The role of a cysteine and glutathione deficiency in the immunopathology of HIV infection. Acta Microbiol Immunol Hung 41 (Suppl): 17–20.
Kinscherf R, Fischbach T, Mihm S, Roth S, Hohenhaus-Sievert E, Weiss C, Edler L, Bärtsch P, Dröge W (1994). Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ T cells. FASEB J 8: 448-451.
1993
Dröge W, Rouse S, Murthy K, Stahl-Hennig C, Hartung S, Plesker R, Peterhans E, Kinscherf R, Fischbach T, Eck HP (1993). Plasma amino acid dysregulation after lentiviral infection. AIDS Res Hum Retrovir 9: 807-809.
Kinscherf R, Kirschfink M, Strobel G, Weicker H (1993). Influence on myoadenylatedeamina-se function in rat skeletal muscle after homologous and heterologous immunezation with the purified enzyme. Int J of Sports Med 14: 214-219.
Sziegoleit A, Müller M, Wilhelm B, Linder M, Linder D (1993). Human 1-antichymotrypsin of pancreatic origin carries blood group determinants. Biol Chem 374: 455-459.
Strobel G, Hack V, Kinscherf R, Weicker H (1993). Plasma norepinephrine sulfates reflect increased sympathetic activity until two hours after exercise. Eur J Appl Physiol 66: 421-426.