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Ausgewählte Publikationen

Shirafkan, F., Hensel, L. and Rattay, K. (2024) Immune tolerance and the prevention of autoimmune diseases essentially depend on thymic tissue homeostasis. Front Immunol. 15, 1339714.

Lammers, S., Barrera, V., Brennecke, P., Miller, C., Yoon, J., Balolong, J., Anderson, M.S., Ho Sui, S., Steinmetz, L.M., von Andrian, U.H. and Rattay, K. (2024) Ehf and Fezf2 regulate late medullary thymic epithelial cell and thymic tuft cell development. Front. Immunol. 14:1277365. 

Sundaresan, B., Shirafkan, F., Ripperger, K., and Rattay, K. (2023). The Role of Viral Infections in the Onset of Autoimmune Diseases. Viruses 15(3), 782.

Vollmann, E. H., Rattay, K., Barreiro, O., Thiriot, A., Fuhlbrigge, R. A., Vrbanac, V., Kim, K., Jung, S., Tager, A. M. & von Andrian, U. H. (2021). Specialized transendothelial dendritic cells mediate thymic T-cell selection against blood-borne macromolecules. Nat Commun 12, 6230.

Miller, C.N., Proekt, I., von Moltke, J., Wells, K.L., Rajpurkar, A.R., Wang, H., Rattay, K., Khan, I.S., Metzger, T.C., Pollack, J.L., et al. (2018). Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature 559, 627-631.

Rattay, K., Meyer, H.V., Herrmann, C., Brors, B., and Kyewski, B. (2016). Evolutionary conserved gene co-expression drives generation of self-antigen diversity in medullary thymic epithelial cells. J Autoimmun 67, 65-75.

Brennecke, P., Reyes, A., Pinto, S., Rattay, K., Nguyen, M., Kuchler, R., Huber, W., Kyewski, B., and Steinmetz, L.M. (2015). Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells. Nat Immunol 16, 933-941.

Ucar, O. and Rattay, K. (2015). Promiscuous gene expression in the thymus: a matter of epigenetics, miRNA and more? Front. Immunol., vol. 6, p. 93.
Cancer Res Jan 15;82(2):210-220. DOI: 10.1158/0008-5472.CAN-21-1261

Rattay, K., Claude, J., Rezavandy, E., Matt, S., Hofmann, T.G., Kyewski, B., and Derbinski, J. (2015). Homeodomain-interacting protein kinase 2, a novel autoimmune regulator interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells. J Immunol 194, 921-928.