Publikationen

Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D, Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth E, Daum P, Wanzel M, Mernberger M, Nist A, Bauer UM, Helmprobst F, Buchholz M, Roth K, Bastian L, Hartmann AM, Baldus C, Ikuta K, Neubauer A, Burchert A, Jäck HM, Klein M, Bopp T, Stiewe T, Pagenstecher A, Lohoff
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity. 
M.Cell Death Differ. 2022 Apr 22. doi: 10.1038/s41418-022-01005-z. Online ahead of print.PMID: 35459909

Karikari AA, McFleder RL, Ribechini E, Blum R, Bruttel V, Knorr S, Gehmeyr M, Volkmann J, Brotchie JM, Ahsan F, Haack B, Monoranu CM, Keber U, Yeghiazaryan R, Pagenstecher A, Heckel T, Bischler T, Wischhusen J, Koprich JB, Lutz MB, Ip CW.
Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson's disease mice.
Brain Behav Immun. 2022 Mar;101:194-210. doi: 10.1016/j.bbi.2022.01.007. Epub 2022 Jan 12.PMID: 35032575 Free article.

Zhao K, Schäfer A, Zhang Z, Elsässer K, Culmsee C, Zhong L, Pagenstecher A, Nimsky C, Bartsch JW.
Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells.
Int J Mol Sci. 2021 Dec 23;23(1):157. doi: 10.3390/ijms23010157.

Helmprobst F, Kneitz S, Klotz B, Naville M, Dechaud C, Volff JN, Schartl M.
Differential expression of transposable elements in the medaka melanoma model.
PLoS One. 2021 Oct 27;16(10):e0251713. doi: 10.1371/journal.pone.0251713. eCollection 2021.PMID: 34705830 Free PMC article.

 Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, Pagenstecher A, Kupke A, Enquist LW, Perlman S.
Post-viral effects of COVID-19 in the olfactory system and their implications.
Lancet Neurol. 2021 Sep;20(9):753-761. doi: 10.1016/S1474-4422(21)00182-4. Epub 2021 Jul 30.PMID: 34339626

Lautenschlaeger FS, Dumke R, Schymalla M, Hauswald H, Carl B, Stein M, Keber U, Jensen A, Engenhart-Cabillic R, Eberle F.
Comparison of carbon ion and photon reirradiation for recurrent glioblastoma.
Strahlenther Onkol. 2022 May;198(5):427-435. doi: 10.1007/s00066-021-01844-8. Epub 2021 Sep 14.PMID: 34523017 Free PMC article.

Much CD, Sendtner BS, Schwefel K, Freund E, Bekeschus S, Otto O, Pagenstecher A, Felbor U, Rath M, Spiegler S.
Inactivation of Cerebral Cavernous Malformation Genes Results in Accumulation of von Willebrand Factor and Redistribution of Weibel-Palade Bodies in Endothelial Cells.
Front Mol Biosci. 2021 Jul 9;8:622547. doi: 10.3389/fmolb.2021.622547. eCollection 2021.PMID: 34307446

Glöss S, Jurmeister P, Thieme A, Schmid S, Cai WY, Serrette RN, Perner S, Ribbat-Idel J, Pagenstecher A, Bläker H, Keber U, Stadelmann C, Zechel S, Johann PD, Hasselblatt M, Paulus W, Thomas C, Dohmen H, Baumhoer D, Frank S, Agaimy A, Schüller U, Vasudevaraja V, Snuderl M, Liu CZ, Pfister DG, Jungbluth AA, Ghossein RA, Xu B, Capper D, Dogan S.
IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies: Forty Molecularly Homogenous and Histologically Variable Cases With Favorable Outcome.
Am J Surg Pathol. 2021 Sep 1;45(9):1190-1204. doi: 10.1097/PAS.0000000000001697.PMID: 34265800

Ivanova E, Sharma SD, Brichkina A, Pfefferle P, Keber U, Pagenstecher A, Lauth M.
DYRK3 contributes to differentiation and hypoxic control in neuroblastoma.
Biochem Biophys Res Commun. 2021 Aug 27;567:215-221. doi: 10.1016/j.bbrc.2021.06.053. Epub 2021 Jun 22.PMID: 34171798

Verel-Yilmaz Y, Fernández JP, Schäfer A, Nevermann S, Cook L, Gercke N, Helmprobst F, Jaworek C, Pogge von Strandmann E, Pagenstecher A, Bartsch DK, Bartsch JW, Slater
Extracellular Vesicle-Based Detection of Pancreatic Cancer.
EP.Front Cell Dev Biol. 2021 Jul 23;9:697939. doi: 10.3389/fcell.2021.697939. eCollection 2021.PMID: 34368146 Free PMC article.

Ritschel N, Radbruch H, Herden C, Schneider N, Dittmayer C, Franz J, Thomas C, Silva Boos G, Pagenstecher A, Schulz-Schaeffer W, Stadelmann C, Glatzel M, Heppner FL, Weis J, Sohrabi K, Schänzer A, Németh A, Acker T; DGNN-Taskforce „CNS-COVID19“; „DEFEAT PANDEMIcs – Neuropathologische Referenzdiagnostik bei COVID-19“.
[COVID-19 and the central and peripheral nervous system].
Pathologe. 2021 Mar;42(2):172-182. doi: 10.1007/s00292-021-00924-x. Epub 2021 Mar 1.PMID: 33646363 

Hupfer A, Brichkina A, Koeniger A, Keber C, Denkert C, Pfefferle P, Helmprobst F, Pagenstecher A, Visekruna A, Lauth M.
Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche. 
Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2105367118. doi:10.1073/pnas.2105367118.PMID: 34588305 Free PMC article.

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Keber U, Tong CK.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8.PMID: 33634751 

Li Y, Guo S, Zhao K, Conrad C, Driescher C, Rothbart V, Schlomann U, Guerreiro H, Bopp MH, König A, Carl B, Pagenstecher A, Nimsky C, Bartsch JW. 
ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis. 
Biol Chem. 2020 Sep 11;402(2):195-206. doi: 10.1515/hsz-2020-0184. Print 2021 Jan 27.PMID: 33544472

Thome I, Lacle R, Voß A, Bortolussi G, Pantazis G, Schmidt A, Conrad C, Jacob R, Timmesfeld N, Bartsch JW, Pagenstecher A.
Neoplastic Cells are the Major Source of MT-MMPs in IDH1-Mutant Glioma, Thus Enhancing Tumor-Cell Intrinsic Brain Infiltration.
Cancers (Basel). 2020 Aug 29;12(9):E2456. doi: 10.3390/cancers12092456.

Didona D, Juratli HA, Scarsella L, Keber U, Eming R, Hertl M.
Amyopathic and anti-TIF1 gamma-positive dermatomyositis: analysis of a monocentric cohort and proposal to update diagnostic criteria. 
Eur J Dermatol. 2020 Jun 1;30(3):279-288. doi: 10.1684/ejd.2020.3766.

Rath M, Pagenstecher A, Hoischen A, Felbor U.
Postzygotic mosaicism in cerebral cavernous malformation.
J Med Genet. 2020 Mar;57(3):212-216. 

Fassin AK, Knake S, Strzelczyk A, Josephson CB, Reif PS, Haag A, Carl B, Hermsen AM, Gorny I, Möller L, Pagenstecher A, Nimsky C, Bauer S, Sure U, Menzler K, Rosenow F, Klein KM.
Predicting outcome of epilepsy surgery in clinical practice: Prediction models vs. clinical acumen.
Seizure. 2020 Feb 1;76:79-83. 

Hannen R, Selmansberger M, Hauswald M, Pagenstecher A, Nist A, Stiewe T, Acker T, Carl B, Nimsky C, Bartsch JW.
Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase CA2 Gene as Resistance Factor.
Cancers (Basel). 2019 Jun 30;11(7):921.

Kepser LJ, Damar F, De Cicco T, Chaponnier C, Prószyński TJ, Pagenstecher A, Rust MB.
CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.
Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8397-8402.

Visekruna A, Hartmann S, Sillke YR, Glauben R, Fischer F, Raifer H, Mollenkopf H, Bertrams W, Schmeck B, Klein M, Pagenstecher A, Lohoff M, Jacob R, Pabst O, Bland PW, Luu M, Romero R, Siegmund B, Rajalingam K, Steinhoff U.
Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells.
J Clin Invest. 2019 Apr 2;129(5):1972-1983.

Beck-Wödl S, Harzer K, Sturm M, Buchert R, Olaf Rieß O, Mennel HD, Latta E, Pagenstecher A, Keber U.
Homozygous TBC1 domain-containing kinase (TBCK) mutation causes a novel lysosomal storage disease - a new type of neuronal ceroid lipofuscinosis (CLN15)? 
Acta Neuropathol Commun. 2018 Dec 27;6(1):145.

Conrad C, Götte M, Schlomann U, Roessler M, Pagenstecher A, Anderson P, Preston J, Pruessmeyer J, Ludwig A, Li R, Kamm RD, Ritz R, Carl B, Nimsky C, Bartsch JW.
ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells.
Int J Cancer. 2018 Feb 15;142(4):779-791.

Spiegler S, Rath M, Hoffjan S, Dammann P, Sure U, Pagenstecher A, Strom T, Felbor U.
First large genomic inversion in familial cerebral cavernous malformation identified by whole genome sequencing.
Neurogenetics. 2018 Jan;19(1):55-59.

Strik H, Keber U, Hammoud WA, Riera-Knorrenschild J, Carl B, Dodel R, Pagenstecher A, Neubauer A.
Immune checkpoint inhibitor-associated CNS autoimmune disorder (ICICAD) following nivolumab treatment: A new entity of drug-induced autoimmune encephalitis? 
Eur J Cancer. 2017 Dec;87:205-208.

Regensburger M, Türk M, Pagenstecher A, Schröder R, Winkler J.
VCP-related multisystem proteinopathy presenting as early-onset Parkinson disease.
Neurology. 2017 Aug 15;89(7):746-748.

Zöllner JP, Haag A, Hermsen A, Bauer S, Stahl F, Wulf K, Menzler K, Reif PS, Wagner M, Pagenstecher A, Sure U, Knake S, Rosenow F, Strzelczyk A. 
Ictal conduction aphasia and ictal angular gyrus syndrome as rare manifestations of epilepsy: The importance of ictal testing during video-EEG monitoring.
Epilepsy Behav Case Rep. 2017 Aug 3;8:55-62.

Klietz M *, Keber U*, Carlsson T, Chiu WH, Höglinger GU, Weihe E, Schäfer MK, Depboylu C.
l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons.
Neuroscience. 2016 Sep 7;331:120-33.

Seger S, Stritt M, Doppler K, Frank S, Panaite A, Kuntzer T, Steck A, Pagenstecher A, Sommer C, Stalder AK.
A semi-automated method to assess intraepidermal nerve fiber density in human skin biopsies.
Histopathology. 2016  68: 657-665

Höglinger GU, Alvarez-Fischer D, Arias-Carrión O, Djufri M, Windolph A, Keber U, Borta A, Ries V, Schwarting RK, Scheller D, Oertel WH.
A new dopaminergic nigro-olfactory projection.
Acta Neuropathol. 2015;130(3):333-48

Keber U, Klietz M, Carlsson T, Oertel WH, Weihe E, Schäfer MK, Höglinger GU, Depboylu C.
Striatal tyrosine hydroxylase-positive neurons are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
Neuroscience. 2015 Jul 9;298:302-17. doi: 10.1016/j.neuroscience.2015.04.021.

Mikaelyan A, Thompson CL, Hofer MJ, Brune A
Deterministic Assembly of Complex Bacterial Communities in Guts of Germ-Free Cockroaches
Appl Environ Microbiol. 2015 11;82(4):1256-63

Teymoortash A, Zieger L, Hoch S, Pagenstecher A, Hofer MJ.
Distinct microscopic features of perineural invasion in adenoid cystic carcinoma of the head and neck.
Histopathology. 2014 Jun;64(7):1037-9

Seyfer P, Pagenstecher A, Mandic R, Klose KJ, Heverhagen JT.
Cancer and inflammation: differentiation by USPIO-enhanced MR imaging.
J Magn Reson Imaging. 2014 Mar;39(3):665-72

Stellzig J, Chariot A, Shostak K, Ismail Göktuna S, Renner F, Acker T, Pagenstecher A, Schmitz ML
Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways.
Oncogenesis. 2013 Nov 11;2:e79

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E.
IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.
J Immunol. 2013 Oct 1;191(7):3913-21

Radke J, Bortolussi G, Pagenstecher A.
Correction: Akt and c-Myc Induce Stem-Cell Markers in Mature Primary p53 -/- Astrocytes and Render These Cells Gliomagenic in the Brain of Immunocompetent Mice.
PLoS One. 2013 Oct 23;8(10).

El Hindy N, Keyvani K, Pagenstecher A, Dammann P, Sandalcioglu IE, Sure U, Zhu Y.
Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme.
Neuro Oncol. 2013 Oct;15(10):1366-78

Bujan B, Hofer MJ, Oertel WH, Pagenstecher A, Bürk K.
Multiple system atrophy of the cerebellar type (MSA-C) with concomitant beta-amyloid and tau pathology.
Clin Neuropathol. 2013 Jul-Aug;32(4):286-90

Li W, Hofer MJ, Noçon AL, Manders P, Campbell IL.
Interferon regulatory factor 7 (IRF7) is required for the optimal initial control but not subsequent clearance of lymphocytic choriomeningitis virus infection in mice.
Virology. 2013 May 10;439(2):152-62 

Timofeev O, Schlereth K, Wanzel M, Braun A,
Nieswandt B, Pagenstecher A, Rosenwald A, Elsässer HP, Stiewe T.
p53 DNA binding cooperativity is essential for apoptosis and tumor suppression in vivo.
Cell Rep. 2013 May 30;3(5):1512-25

Radke J, Bortolussi G, Pagenstecher A.
Akt and c-Myc induce stem-cell markers in mature primary p53⁻/⁻ astrocytes and render these cells gliomagenic in the brain of immunocompetent mice.
PLoS One. 2013;8(2):e56691

Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, Müller M.
CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.
PLoS One. 2013;8(2):e57307

Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, Guralnik A, Bollig N, Jeltsch K, Heinemann C, Wittmann E, Buch T, Prazeres da Costa O, Brüstle A, Brenner D, Mak TW, Mittrücker HW, Tackenberg B, Kamradt T, Lohoff M.
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.
J Clin Invest. 2013 Jan 2;123(1):247-60.

Hofer MJ, Rohlfs J, Teymoortash A, Pagenstecher A.
A 62-year-old female with an intranasal mass extending into the lamina cribrosa.
Brain Pathol. 2013 Jan;23(1):105-8.

Ghandourah S, Hofer MJ, Kießling A, El-Zayat B, Schofer MD.
Painful muscle fibrosis following synthol injections in a bodybuilder: a case report.
J Med Case Rep. 2012 Aug 20;6(1):248 

Hofer MJ, Riehmer V, Kuhnt D, Braun V, Nimsky C, Weber RG, Sommer C, Pagenstecher A.
Genomic profiling to assess the clonal relationship between histologically distinct intracranial tumours.
Neuropathol Appl Neurobiol. 2012 Aug;38(5):500-4

Hofer MJ, Li W, Manders P, Terry R, Lim SL, King NJ, Campbell IL.
Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.
J Virol. 2012 Jun;86(12):6932-46.

Ip JP, Noçon AL, Hofer MJ, Lim SL, Müller M, Campbell IL.
Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration.
J Neuroinflammation. 2011 Sep 26;8:124 

Pohling C, Buckup T, Pagenstecher A, Motzkus M.
Chemoselective imaging of mouse brain tissue via multiplex CARS microscopy.
Biomed Opt Express. 2011 Aug 1;2(8):2110-6.

Renner F, Saul VV, Pagenstecher A, Wittwer T, Schmitz ML.
Inducible SUMO modification of TANK alleviates its repression of TLR7 signalling.
EMBO Rep. 2011 Feb;12(2):129-35.

Kolodziej M, Benes L, Nimsky C, Schaefer HE, Pagenstecher A.
A 54-year-old woman with a meningeal lesion compressing the medulla oblongata.
Brain Pathol. 2010 Nov20(6):1107-10.

Menzler K, Chen X, Thiel P, Iwinska-Zelder J, Miller D, Reuss A, Hamer HM, Reis J, Pagenstecher A, Knake S, Bertalanffy H, Rosenow F, Sure U.
Epileptogenicity of cavernomas depends on (archi-) cortical localization.
Neurosurgery. 2010 Oct;67(4):918-24

Müller M, Carter S, Hofer MJ, Campbell IL.
Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrum.
Neuropathol Appl Neurobiol. 2010 Aug;36(5):368-87.

Sonar SS, Hsu YM, Conrad ML, Majeau GR, Kilic A, Garber E, Gao Y, Nwankwo C, Willer G, Dudda JC, Kim H, Bailly V, Pagenstecher A, Rennert PD, Renz H.
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.
J Clin Invest. 2010 Jul 12. pii: 39543. [Epub ahead of print]

Althoff GE, Wolfer DP, Timmesfeld N, Kanzler B, Schrewe H, Pagenstecher A.
Long-Term Expression of Tissue-Inhibitor of Matrix Metalloproteinase-1 in the Murine Central Nervous System Does Not Alter the Morphological and Behavioral Phenotype but Alleviates the Course of Experimental Allergic Encephalomyelitis.
Am J Pathol. 2010 Jun 17. [Epub ahead of print]

Ellis SL, Gysbers V, Manders PM, Li W, Hofer MJ, Müller M, Campbell IL.
The Cell-Specific Induction of CXC Chemokine Ligand 9 Mediated by IFN-{gamma} in Microglia of the Central Nervous System Is Determined by the Myeloid Transcription Factor PU.1.
J Immunol. 2010 Jun 28. [Epub ahead of print] 

Thompson CL, Hofer MJ, Campbell IL, Holmes AJ.
Community dynamics in the mouse gut microbiota: a possible role for IRF9-regulated genes in community homeostasis.
PLoS One. 2010 Apr 23;5(4):e10335.

Hofer MJ, Li W, Lim SL, Campbell IL.
The type I interferon-alpha mediates a more severe neurological disease in the absence of the canonical signaling molecule interferon regulatory factor 9.
J Neurosci. 2010 Jan 20;30(3):1149-57.

Campbell IL, Hofer MJ, Pagenstecher A.
Transgenic models for cytokine-induced neurological disease.
Biochim Biophys Acta. 2009 Oct 14. [Epub ahead of print]

Vetter M, Hofer MJ, Roth E, Pircher HP, Pagenstecher A. 
Intracerebral interleukin 12 induces glioma rejection in the brain predominantly by CD8+ T cells and independently of interferon-gamma
J Neuropathol Exp Neurol. 2009 May;68(5):525-34.

Zhu Y, Wloch A, Wu Q, Peters C, Pagenstecher A, Bertalanffy H, Sure U.
Involvement of PTEN promoter methylation in cerebral cavernous malformations.
Stroke. 2009 Mar;40(3):820-6.

Pagenstecher A, Stahl S, Sure U, Felbor U.
A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells.
Hum Mol Genet. 2009 Mar 1;18(5):911-8.

Zhu Y, Peters C, Hallier-Neelsen M, Miller D, Pagenstecher A, Bertalanffy H, Sure U.
Phosphatase and tensin homolog in cerebral cavernous malformation: a potential role in pathological angiogenesis.
J Neurosurg. 2009 Mar;110(3):530-9.

Scheithauer BW, Kovacs K, Nose V, Lombardero M, Osamura YR, Lloyd RV, Horvath E, Pagenstecher A, Bohl JE, Tews DS.
Multiple endocrine neoplasia type 1-associated thyrotropin-producing pituitary carcinoma: report of a probable de novo example.
Hum Pathol. 2009 Feb;40(2):270-8.

Quintana A, Müller M, Frausto RF, Ramos R, Getts DR, Sanz E, Hofer MJ, Krauthausen M, King NJ, Hidalgo J, Campbell IL.
Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis.
J Immunol. 2009 Aug 1;183(3):2079-88. Epub 2009 Jul 13.

 Wang LF, Fokas E, Juricko J, You A, Rose F, Pagenstecher A, Engenhart-Cabillic R, An HX.
Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients.
BMC Cancer. 2008 Mar 25;8:79.

Baur K, Rauer M, Richter K, Pagenstecher A, Götz J, Hausmann J, Staeheli P.
Antiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytes.
J Virol. 2008 Mar;82(6):3099-108.

Wang LF, Fokas E, Bieker M, Rose F, Rexin P, Zhu Y, Pagenstecher A, Engenhart-Cabillic R, An HX.
Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients.
Oncol Rep. 2008 Jan;19(1):151-6.

Miller D, Knake S, Bauer S, Krakow K, Pagenstecher A, Sure U, Rosenow F.
Intraoperative ultrasound to define focal cortical dysplasia in epilepsy surgery.
Epilepsia. 2008 Jan;49(1):156-8.

Hofer MJ, Carter SL, Müller M, Campbell IL.
Unaltered neurological disease and mortality in CXCR3-deficient mice infected intracranially with lymphocytic choriomeningitis virus-Armstrong.
Viral Immunol. 2008 Dec;21(4):425-33.

Sanz E, Hofer MJ, Unzeta M, Campbell IL.
Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain.
Glia. 2008 Jan 15;56(2):190-9.

Driller K, Pagenstecher A, Uhl M, Omran H, Berlis A, Grunder A, Sippel AE. 
Nuclear factor I X deficiency causes brain malformation and severe skeletal defects.
Mol Cell Biol. 2007 May;27(10):3855-3867.

Müller M, Carter SL, Hofer MJ, Manders P, Getts DR, Getts MT, Dreykluft A, Lu B, Gerard C, King NJ, Campbell IL.
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system.
J Immunol. 2007 Sep 1;179(5):2774-86.

Wacher C, Muller M, Hofer MJ, Getts DR, Zabaras R, Ousman SS, Terenzi F, Sen GC, King NJ, Campbell IL.
Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.
J Virol. 2007 Jan; 81(2): 860-871

Sohlbach K,Heinze S,Shiratori K,Sure U,Pagenstecher A,Neubauer A.
Encephalopathy in a patient after long-term treatment with thalidomide.
J Clin Oncol. 2006 Oct 20;24(30):4942-4.

Wildeboer D, Naus S, Amy Sang QX, Bartsch JW, Pagenstecher A.
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness
J Neuropathol Exp Neurol. 2006 May;65(5):516-27.

Van den Steen PE, Van Aelst I, Starckx S, Maskos K, Opdenakker G, Pagenstecher A. 
Matrix metalloproteinases, tissue inhibitors of MMPs and TACE in experimental cerebral malaria.
Lab Invest. 2006 Sep;86(9):873-88. PMID: 16865090

Hofer MJ, Schindler AR, Ehrensperger F, Staeheli P, Pagenstecher A. 
Absence of Borna disease virus in the CNS of epilepsy patients.
J Clin Virol. 2006 Feb 20;

Hausmann J, Pagenstecher A, Baur K, Richter K, Rziha HJ, Staeheli P.
CD8 T cells require gamma interferon to clear borna disease virus from the brain and prevent immune system-mediated neuronal damage.
J Virol. 2005 Nov;79(21):13509-18.

Lutterbach J, Pagenstecher A, Weyerbrock A, Schultze-Seemann W, Waller CF. 
Early-stage penile carcinoma metastasizing to brain: case report and literature review.
Urology. 2005 Aug;66(2):432. Review.

Hofer MJ, Finger C, Pagenstecher A. 
Molecular genotyping of the murine H-2K MHC class I allele.
J Immunol Methods. 2005 Jul;302(1-2):168-71.

Glasker S, Berlis A, Pagenstecher A, Vougioukas VI, Van Velthoven V. 
Characterization of hemangioblastomas of spinal nerves.
Neurosurgery. 2005 Mar;56(3):503-9; discussion 503-9. Review.

Hofer M, Hausmann J, Staeheli P, Pagenstecher A.
Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice.
Am J Pathol. 2004 Sep;165(3):949-58.

Hofer M, Weber A, Haffner K, Berlis A, Klingel K, Krüger M, Kandolf R, Volk B 
Acute hemorrhagic leukoencephalitis (Hurst’s disease) linked to Epstein-Barr virus infection
Acta Neuropathol 2005 March; 109: 226–230

Harloff A, Rauer S, Hofer M, Klisch J, Els T
Fulminant acute disseminated encephalomyelitis mimicking acute bacterial meningoencephalitis
European Journal of Neurology 2005 Jan; 12: 67-69

Ibanez-Tallon I, Pagenstecher A, Fliegauf M, Olbrich H, Kispert A, Ketelsen UP, North A, Heintz N, Omran H. 
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation.
Hum Mol Genet. 2004 Sep 15;13(18):2133-41.

Blaser S, Horn J, Wurmell P, Bauer H, Strumpell S, Nurden P, Pagenstecher A, Busse A, Wunderle D, Hainmann I, Zieger B. 
The novel human platelet septin SEPT8 is an interaction partner of SEPT4.
Thromb Haemost. 2004 May;91(5):959-66.

Friedl G, Hofer M, Auber B, Sauder C, Hausmann J, Staeheli P, Pagenstecher A.
Borna disease virus multiplication in mouse organotypic slice cultures is site-specifically inhibited by gamma interferon but not by interleukin-12.
J Virol. 2004 Feb;78(3):1212-8.

Crocker SJ, Pagenstecher A, Campbell IL. 
The TIMPs tango with MMPs and more in the central nervous system.
J Neurosci Res. 2004 Jan 1;75(1):1-11. Review.

Lutterbach J, Henne K, Pagenstecher A, Bohm J. 
Lung cancer and Rosai-Dorfman's disease. A clinicopathological study.
Strahlenther Onkol. 2003 Jul;179(7):486-92.

Aicher WK, Alexander D, Haas C, Kuchen S, Pagenstecher A, Gay S, Peter HH, Eibel H. 
Transcription factor early growth response 1 activity up-regulates expression of tissue inhibitor of metalloproteinases 1 in human synovial fibroblasts.
Arthritis Rheum. 2003 Feb;48(2):348-59.

Weissenbock H, Bilzer T, Ehrensperger F, Gosztonyi G, Herden C, Staehli P, Hausmann J, Pagenstecher A. 
Equine borna disease in Japan.
Vet Rec. 2002 Dec 7;151(23):712; 

Freude S, Hausmann J, Hofer M, Pham-Mitchell N, Campbell IL, Staeheli P, Pagenstecher A. 
Borna disease virus accelerates inflammation and disease associated with transgenic expression of interleukin-12 in the central nervous system.
J Virol. 2002 Dec;76(23):12223-32.

Dubois B, Starckx S, Pagenstecher A, Oord J, Arnold B, Opdenakker G.
Gelatinase B deficiency protects against endotoxin shock.
Eur J Immunol. 2002 Aug;32(8):2163-71.

Lutterbach J, Fauchon F, Schild SE, Chang SM, Pagenstecher A, Volk B, Ostertag C, Momm F, Jouvet A. 
Malignant pineal parenchymal tumors in adult patients: patterns of care and prognostic factors.
Neurosurgery. 2002 Jul;51(1):44-55; discussion 55-6. Review. 

Lutterbach J, Spetzger U, Bartelt S, Pagenstecher A.
Malignant germ cell tumors metastatic to the brain: a model for a curable neoplasm? The Freiburg experience and a review of the literature.
J Neurooncol. 2002 Jun;58(2):147-56. Review.

Klisch J, Schellhammer F, Zitt J, Scheufler KM, Pagenstecher A, Nagursky H, Schumacher M.
Combined stent implantation and embolization with liquid 2-polyhydroxyethyl methacrylate for treatment of experimental canine wide-necked aneurysms.
Neuroradiology. 2002 Jun;44(6):503-12.

Rauer M, Pagenstecher A, Schulte-Monting J, Sauder C.
Upregulation of chemokine receptor gene expression in brains of Borna disease virus (BDV)-infected rats in the absence and presence of inflammation.
J Neurovirol. 2002 Jun;8(3):168-79.

Klisch J, Yin L, Requejo F, Eissner B, Scheufler KM, Kubalek R, Buechner M, Pagenstecher A, Nagursky H, Schumacher M.
Liquid 2-poly-hydroxyethyl-methacrylate embolization of experimental arteriovenous malformations: feasibility study.
AJNR Am J Neuroradiol. 2002 Mar;23(3):422-9.

Maier J, Kincaid C, Pagenstecher A, Campbell IL.
Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis.
Am J Pathol. 2002 Jan;160(1):271-88.

Khuth ST, Akaoka H, Pagenstecher A, Verlaeten O, Belin MF, Giraudon P, Bernard A. 
Morbillivirus infection of the mouse central nervous system induces region-specific upregulation of MMPs and TIMPs correlated to inflammatory cytokine expression.
J Virol. 2001 Sep;75(17):8268-82.

Allmang U, Hofer M, Herzog S, Bechter K, Staeheli P.
Low avidity of human serum antibodies for Borna disease virus antigens questions their diagnostic value.
Mol Psychiatry. 2001 May; 6(3): 329-333.

Pagenstecher A, Stalder AK, Kincaid CL, Volk B, Campbell IL. 
Regulation of matrix metalloproteinases and their inhibitor genes in lipopolysaccharide-induced endotoxemia in mice.
Am J Pathol. 2000 Jul;157(1):197-210.

Pagenstecher A, Lassmann S, Carson MJ, Kincaid CL, Stalder AK, Campbell IL.
Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis.
J Immunol. 2000 May 1;164(9):4481-92.

Campbell IL, Pagenstecher A. 
Matrix metalloproteinases and their inhibitors in the nervous system: the good, the bad and the enigmatic.
Trends Neurosci. 1999 Jul;22(7):285-7. 

Hausmann J, Hallensleben W, de la Torre JC, Pagenstecher A, Zimmermann C, Pircher H, Staeheli P. 
T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein.
Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9769-74.

Asensio VC, Lassmann S, Pagenstecher A, Steffensen SC, Henriksen SJ, Campbell IL. 
C10 is a novel chemokine expressed in experimental inflammatory demyelinating disorders that promotes recruitment of macrophages to the central nervous system.
Am J Pathol. 1999 Apr;154(4):1181-91.

Czygan M, Hallensleben W, Hofer M, Pollak S, Sauder C, Bilzer T, Blumcke I, Riederer P, Bogerts B, Falkai P, Schwarz MJ, Masliah E, Staeheli P, Hufert FT, Lieb K.
Borna disease virus in human brains with a rare form of hippocampal degeneration but not in brains of patients with common neuropsychiatric disorders.
J Infect Dis. 1999 Nov; 180(5): 1695-1699.

Stalder AK, Carson MJ, Pagenstecher A, Asensio VC, Kincaid C, Benedict M, Powell HC, Masliah E, Campbell IL.
Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor.
Am J Pathol. 1998 Sep;153(3):767-83.

Campbell IL, Stalder AK, Akwa Y, Pagenstecher A, Asensio VC. 
Transgenic models to study the actions of cytokines in the central nervous system.
Neuroimmunomodulation. 1998 May-Aug;5(3-4):126-35. Review.

Hallensleben W, Schwemmle M, Hausmann J, Stitz L, Volk B, Pagenstecher A, Staeheli P. 
Borna disease virus-induced neurological disorder in mice: infection of neonates results in immunopathology.
J Virol. 1998 May;72(5):4379-86.

Pagenstecher A, Stalder AK, Kincaid CL, Shapiro SD, Campbell IL.
Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states.
Am J Pathol. 1998 Mar;152(3):729-41.

Pagenstecher A, Stalder AK, Campbell IL.
RNAse protection assays for the simultaneous and semiquantitative analysis of multiple murine matrix metalloproteinase (MMP) and MMP inhibitor mRNAs.
J Immunol Methods. 1997 Aug 7;206(1-2):1-9.

Stalder AK, Pagenstecher A, Yu NC, Kincaid C, Chiang CS, Hobbs MV, Bloom FE, Campbell IL.
Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia.
J Immunol. 1997 Aug 1;159(3):1344-51.

Schellhammer F, Berlis A, Bloss H, Pagenstecher A, Schumacher M.
Poly-lactic-acid coating for endovascular stents. Preliminary results in canine experimental arteriovenous fistulae.
Invest Radiol. 1997 Mar;32(3):180-6.

Pagenstecher A, Kirk J, Dermott E, Ostertag C, Volk B.
Large, virus-like sinuous tubules in the endoplasmic reticulum of human neurons: report from a case of encephalopathy and brief critical review.
Acta Neuropathol (Berl). 1996 Sep;92(3):294-9.

Kreth FW, Schatz CR, Pagenstecher A, Faist M, Volk B, Ostertag CB.
Stereotactic management of lesions of the pineal region.
Neurosurgery. 1996 Aug;39(2):280-9; discussion 289-91.

Pagenstecher A, Emmerich B, van Velthoven V, Korinthenberg R, Volk B.
Exclusively intracranial cranial fasciitis in a child. Case report.
J Neurosurg. 1995 Oct;83(4):744-7.

Pagenstecher A, Franz M, Volk B. 
[A case of paraneoplastic limbic encephalitis in autoptic occult primary malignancy]
Nervenarzt. 1994 Aug;65(8):549-52.

Lamminger C, Pagenstecher A, Schroter R. 
[Lichen ruber only in skin areas exposed to light]
Hautarzt. 1991 Jan;42(1):48-9.