Hauptinhalt

• Publikationen

+ 2024 

• Zubeldia-Varela E, Blanco-Pérez F, Barker-Tejeda TC, Rojo D, Villaseñor A, Islam J, Gonzalez-Menendez I, Laiño J, Krause M, Steigerwald H, Martella M, Quintanilla-Martinez L, Yu P, Barbas C, Vieths S, Nochi T, Barber D, Toda M, Pérez-Gordo M. The impact of high-IgE levels on metabolome and microbiome in experimental allergic enteritis. Allergy. 2024 Jun 23. doi: 10.1111/all.16202. Epub ahead of print. PMID: 38932655.
• Vargas-Calderón H, Ortega-Robles E, Rocha L, Yu P, Arias-Carrión O. Motor, Cognitive, and Behavioral Impairment in TLR3 and TLR9 Deficient Male Mice: Insights into the Non-Immunological Roles of Toll-Like Receptors. Arch Med Res. 2024 Mar 22;55(3):102985. doi: 10.1016/j.arcmed.2024.102985. Epub ahead of print. PMID: 38520880.
• Venegas-Solis F, Staliunaite L, Rudolph E, Münch CC, Yu P, Freibert SA, Maeda T, Zimmer CL, Möbs C, Keller C, Kaufmann A, Bauer S. A type I interferon regulatory network for human plasmacytoid dendritic cells based on heparin, membrane-bound and soluble BDCA-2. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2312404121. doi: 10.1073/pnas.2312404121. Epub 2024 Mar 13. PMID: 38478694.
• Gerlach RG, Wittmann I, Heinrich L, Pinkenburg O, Meyer T, Elpers L, Schmidt C, Hensel M and Schnare M (2024) Subversion of a family of antimicrobial proteins by Salmonella enterica. Front. Cell. Infect. Microbiol. 14:1375887. doi: 10.3389/fcimb.2024.1375887
• Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian B. Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl , Ingo Burtscher, Sonja Dehnert, Chege Kuria, Alexandra Kupke, Stephanie Paul, Thomas Liehr, Marcus Lechner , Markus Schnare, Andreas Kaufmann, Magdalena Huber, Thomas H. Winkler , Stefan Bauer & Philipp Yu T-bet+ B cells are activated by and control endogenous retroviruses through TLR- dependent mechanisms; Nature Communications | (2024)15:1229

• Inhalt ausklappen Inhalt einklappen 2012

Jockel, S., G. Nees, R. Sommer, Y. Zhao, D. Cherkasov, H. Hori, G. Ehm, M. Schnare, M. Nain, A. Kaufmann, and S. Bauer. 2012. The 2'-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition. J Exp Med 209:235-241.

Obermann, H. L., and S. Bauer. 2012. Toll-like receptor 9, what o'clock is it? Immunity 36:159-161.

• Inhalt ausklappen Inhalt einklappen

  • Koppe, U., K. Hogner, J. M. Doehn, H. C. Muller, M. Witzenrath, B. Gutbier, S. Bauer, T. Pribyl, S. Hammerschmidt, J. Lohmeyer, N. Suttorp, S. Herold, and B. Opitz. 2012. Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J Immunol 188:811-817.
  • Dicke, T., I. Pali-Scholl, A. Kaufmann, S. Bauer, H. Renz, and H. Garn. 2012. Absence of unspecific innate immune cell activation by GATA-3-specific DNAzymes. Nucleic Acid Ther 22:117-126.

• Inhalt ausklappen Inhalt einklappen 2011

  • Prinz, N., N. Clemens, D. Strand, I. Putz, M. Lorenz, A. Daiber, P. Stein, A. Degreif, M. Radsak, H. Schild, S. Bauer, P. von Landenberg, and K. J. Lackner. 2011. Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells. Blood 118:2322-2332.
    
    
  • Lippmann, J., H. C. Muller, J. Naujoks, C. Tabeling, S. Shin, M. Witzenrath, K. Hellwig, C. J. Kirschning, G. A. Taylor, W. Barchet, S. Bauer, N. Suttorp, C. R. Roy, and B. Opitz. 2011. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol 13:1668-1682.
    
    
  • Klaffenbach, D., D. Friedrich, R. Strick, P. L. Strissel, M. W. Beckmann, W. Rascher, A. Gessner, J. Dotsch, U. Meissner, and M. Schnare. 2011. Contribution of different placental cells to the expression and stimulation of antimicrobial proteins (AMPs). Placenta 32:830-837.
  • Jantsch, J., M. Wiese, J. Schodel, K. Castiglione, J. Glasner, S. Kolbe, D. Mole, U. Schleicher, K. U. Eckardt, M. Hensel, R. Lang, C. Bogdan, M. Schnare, and C. Willam. 2011. Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1alpha (HIF1A) and result in differential HIF1A-dependent gene expression. J Leukoc Biol 90:551-562.
    
    
  • Groseth, A., T. Hoenen, M. Weber, S. Wolff, A. Herwig, A. Kaufmann, and S. Becker. 2011. Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. PLoS Negl Trop Dis 5:e1137.
    
    
  • Deshmukh, S. D., B. Kremer, M. Freudenberg, S. Bauer, D. T. Golenbock, and P. Henneke. 2011. Macrophages recognize streptococci through bacterial single-stranded RNA. EMBO Rep 12:71-76.
  • Brenner, S., D. Drewel, T. Steinbart, F. Weisel, E. Hartel, S. Potzsch, H. Welzel, A. Brandl, P. Yu, G. C. Mudde, A. Schweizer, L. Nitschke, and T. H. Winkler. 2011. A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing. Embo J 30:2705-2718.
    
    
  • Abe, K., H. Fuchs, A. Boersma, W. Hans, P. Yu, S. Kalaydjiev, M. Klaften, T. Adler, J. Calzada-Wack, I. Mossbrugger, B. Rathkolb, J. Rozman, C. Prehn, M. Maraslioglu, Y. Kametani, S. Shimada, J. Adamski, D. H. Busch, I. Esposito, M. Klingenspor, E. Wolf, W. Wurst, V. Gailus-Durner, M. Katan, S. Marschall, D. Soewarto, S. Wagner, and M. H. de Angelis. 2011. A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cgamma2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis Rheum 63:1301-1311.

• Inhalt ausklappen Inhalt einklappen 2010

  • Lafferty, E. I., S. T. Qureshi, and M. Schnare. 2010. The role of toll-like receptors in acute and chronic lung inflammation. J Inflamm (Lond) 7:57.
    
    
  • Hamm, S., E. Latz, D. Hangel, T. Muller, P. Yu, D. Golenbock, T. Sparwasser, H. Wagner, and S. Bauer. 2010. Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist. Immunobiology 215:559-569.
    
    
  • Elvers, M., R. Pozgaj, I. Pleines, F. May, M. J. Kuijpers, J. M. Heemskerk, P. Yu, and B. Nieswandt. 2010. Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase Cgamma2. J Thromb Haemost 8:1353-1363.
    
    
  • Doring, Y., J. Hurst, M. Lorenz, N. Prinz, N. Clemens, M. D. Drechsler, S. Bauer, J. Chapman, Y. Shoenfeld, M. Blank, K. J. Lackner, and P. von Landenberg. 2010. Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8. Immunobiology 215:230-241.
    
    
  • Bauer, S., B. Bathke, H. Lauterbach, J. Patzold, R. Kassub, C. A. Luber, B. Schlatter, S. Hamm, P. Chaplin, M. Suter, and H. Hochrein. 2010. A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC? Proc Natl Acad Sci U S A 107:E139; author reply E140.

• Inhalt ausklappen Inhalt einklappen 2009

  • Tluk, S., M. Jurk, A. Forsbach, R. Weeratna, U. Samulowitz, A. M. Krieg, S. Bauer, and J. Vollmer. 2009. Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses. Int Immunol 21:607-619.
    
    
  • Shibamiya, A., K. Hersemeyer, T. Schmidt Woll, D. Sedding, J. M. Daniel, S. Bauer, T. Koyama, K. T. Preissner, and S. M. Kanse. 2009. A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells. Blood 113:714-722.
    
    
  • Rad, R., W. Ballhorn, P. Voland, K. Eisenacher, J. Mages, L. Rad, R. Ferstl, R. Lang, H. Wagner, R. M. Schmid, S. Bauer, C. Prinz, C. J. Kirschning, and A. Krug. 2009. Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori. Gastroenterology 136:2247-2257.
    
    
  • Kiemer, A. K., R. H. Senaratne, J. Hoppstadter, B. Diesel, L. W. Riley, K. Tabeta, S. Bauer, B. Beutler, and B. L. Zuraw. 2009. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun 1:29-45.
    
    
  • Hurst, J., N. Prinz, M. Lorenz, S. Bauer, J. Chapman, K. J. Lackner, and P. von Landenberg. 2009. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells. Immunobiology 214:683-691.
    
    
  • Hecker, A., A. Kaufmann, M. Hecker, W. Padberg, and V. Grau. 2009. Expression of interleukin-21, interleukin-21 receptor alpha and related type I cytokines by intravascular graft leukocytes during acute renal allograft rejection. Immunobiology 214:41-49.
    
    
  • Everett, K. L., T. D. Bunney, Y. Yoon, F. Rodrigues-Lima, R. Harris, P. C. Driscoll, K. Abe, H. Fuchs, M. H. de Angelis, P. Yu, W. Cho, and M. Katan. 2009. Characterization of phospholipase C gamma enzymes with gain-of-function mutations. J Biol Chem 284:23083-23093.
    
    
  • Bauer, S., T. Muller, and S. Hamm. 2009. Pattern recognition by Toll-like receptors. Adv Exp Med Biol 653:15-34.

• Inhalt ausklappen Inhalt einklappen 2008

  • Yu, P., P. Musette, and S. L. Peng. 2008. Toll-like receptor 9 in murine lupus: more friend than foe! Immunobiology 213:151-157.
    
    
  • Muller, T., S. Hamm, and S. Bauer. 2008. TLR9-mediated recognition of DNA. Handb Exp Pharmacol:51-70.
    
    
  • Kalali, B. N., G. Kollisch, J. Mages, T. Muller, S. Bauer, H. Wagner, J. Ring, R. Lang, M. Mempel, and M. Ollert. 2008. Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling. J Immunol 181:2694-2704.
    
    
  • Holler, J., A. Zakrzewicz, A. Kaufmann, J. Wilhelm, G. Fuchs-Moll, H. Dietrich, W. Padberg, J. Kuncova, W. Kummer, and V. Grau. 2008. Neuropeptide Y is expressed by rat mononuclear blood leukocytes and strongly down-regulated during inflammation. J Immunol 181:6906-6912.
    
    
  • Guggemoos, S., D. Hangel, S. Hamm, A. Heit, S. Bauer, and H. Adler. 2008. TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol 180:438-443.
    
    
  • Bauer, S., S. Pigisch, D. Hangel, A. Kaufmann, and S. Hamm. 2008. Recognition of nucleic acid and nucleic acid analogs by Toll-like receptors 7, 8 and 9. Immunobiology 213:315-328.

• Inhalt ausklappen Inhalt einklappen 2007

  • von Landenberg, P., and S. Bauer. 2007. Nucleic acid recognizing Toll-like receptors and autoimmunity. Curr Opin Immunol 19:606-610.
    
    
  • Sel, S., M. Wegmann, S. Sel, S. Bauer, H. Garn, G. Alber, and H. Renz. 2007. Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10. J Immunol 178:7805-7813.
    
    
  • Schwarz, H., K. Schneider, A. Ohnemus, M. Lavric, S. Kothlow, S. Bauer, B. Kaspers, and P. Staeheli. 2007. Chicken toll-like receptor 3 recognizes its cognate ligand when ectopically expressed in human cells. J Interferon Cytokine Res 27:97-101.
    
    
  • Schmidt, A., J. Sucke, G. Fuchs-Moll, P. Freitag, M. Hirschburger, A. Kaufmann, H. Garn, W. Padberg, and V. Grau. 2007. Macrophages in experimental rat lung isografts and allografts: infiltration and proliferation in situ. J Leukoc Biol 81:186-194.
    
    
  • Rad, R., L. Brenner, A. Krug, P. Voland, J. Mages, R. Lang, S. Schwendy, W. Reindl, A. Dossumbekova, W. Ballhorn, H. Wagner, R. M. Schmid, S. Bauer, and C. Prinz. 2007. Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori. Gastroenterology 133:150-163 e153.
    
    
  • Porter, M., M. Karp, S. Killedar, S. M. Bauer, J. Guo, D. Williams, P. Breysse, S. N. Georas, and M. A. Williams. 2007. Diesel-enriched particulate matter functionally activates human dendritic cells. Am J Respir Cell Mol Biol 37:706-719.
    
    
  • Hamm, S., A. Heit, M. Koffler, K. M. Huster, S. Akira, D. H. Busch, H. Wagner, and S. Bauer. 2007. Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo. Int Immunol 19:297-304.
    
    
  • Forsbach, A., J. G. Nemorin, K. Volp, U. Samulowitz, C. Montino, C. Muller, S. Tluk, S. Hamm, S. Bauer, G. B. Lipford, and J. Vollmer. 2007. Characterization of conserved viral leader RNA sequences that stimulate innate immunity through TLRs. Oligonucleotides 17:405-417.
    
    
  • Brustle, A., S. Heink, M. Huber, C. Rosenplanter, C. Stadelmann, P. Yu, E. Arpaia, T. W. Mak, T. Kamradt, and M. Lohoff. 2007. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol 8:958-966.
    
    
  • Blocher, S., S. Wilker, J. Sucke, U. Pfeil, H. Dietrich, R. Weimer, K. Steger, A. Kaufmann, M. Hirschburger, C. Plotz, W. Padberg, and V. Grau. 2007. Acute rejection of experimental lung allografts: characterization of intravascular mononuclear leukocytes. Clin Immunol 124:98-108.
    
    
  • Bauer, S., D. Hangel, and P. Yu. 2007. Immunobiology of toll-like receptors in allergic disease. Immunobiology 212:521-533.

• Inhalt ausklappen Inhalt einklappen 2006

  • Yu, P., U. Wellmann, S. Kunder, L. Quintanilla-Martinez, L. Jennen, N. Dear, K. Amann, S. Bauer, T. H. Winkler, and H. Wagner. 2006. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. Int Immunol 18:1211-1219.
    
    
  • Yasuda, K., M. Rutz, B. Schlatter, J. Metzger, P. B. Luppa, F. Schmitz, T. Haas, A. Heit, S. Bauer, and H. Wagner. 2006. CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA. Eur J Immunol 36:431-436.
    
    
  • Wagner, H., and S. Bauer. 2006. All is not Toll: new pathways in DNA recognition. J Exp Med 203:265-268.
    
    
  • von Meyenn, F., M. Schaefer, H. Weighardt, S. Bauer, C. J. Kirschning, H. Wagner, and T. Sparwasser. 2006. Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guerin by Flt3-ligand generated dendritic cells. Immunobiology 211:557-565.
    
    
  • Savarese, E., O. W. Chae, S. Trowitzsch, G. Weber, B. Kastner, S. Akira, H. Wagner, R. M. Schmid, S. Bauer, and A. Krug. 2006. U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 107:3229-3234.
    
    
  • Rad, R., L. Brenner, S. Bauer, S. Schwendy, L. Layland, C. P. da Costa, W. Reindl, A. Dossumbekova, M. Friedrich, D. Saur, H. Wagner, R. M. Schmid, and C. Prinz. 2006. CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology 131:525-537.
    
    
  • Loseke, S., E. Grage-Griebenow, H. Heine, A. Wagner, S. Akira, S. Bauer, and A. Bufe. 2006. In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells. Scand J Immunol 63:264-274.
    
    
  • Bauer, S. 2006. Toll-erating self DNA. Nat Immunol 7:13-15.
    
    
  • Baiyee, E. E., S. Flohe, S. Lendemans, S. Bauer, N. Mueller, E. Kreuzfelder, and H. Grosse-Wilde. 2006. Expression and function of Toll-like receptor 9 in severely injured patients prone to sepsis. Clin Exp Immunol 145:456-462.