AG Graumann

We are studying dynamic processes in bacteria, with a focus on chromosome dynamics and cell shape maintenance. We are interested in several questions that involve the spatial organization and biochemistry of the cell: how is the shape of a bacterium established? How is the cell cycle regulated and driven, and how is DNA transferred between bacteria? As a model for Gram positive bacteria, we use Bacillus subtilis cells, which offer a superb genetic and cell biological system. We are using a combination of state of the art biochemical tools and super resolution fluorescence microscopy to understand how the bacterial cell is organized in 3D, and how cyctosolic and membrane proteins are dynamically positioned within a non-compartmentalized cell.