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News and Highlights from the Meggers Laboratory
Newest Publications
Kuan Yin's work on α-amino acid synthesis (Synthesis 2024, 56, 2670) featured on the cover.
Peng Xiong's asymmetric photoelectrocatalysis (Nat. Catal. 2023, 6, 1186) published as Synfacts.
Xin Nie's oxyamination (Angew. Chem. Int. Ed. 2023, 62, e202314398) published as Synfacts.
Dominik Baran's stereogenic-at-iron publication in EurJIC becomes Reader's Choice!
Xin Nie's nitrene-mediated oxyamination published in Angewandte Chemie: Angew. Chem. Int. Ed. 2023, DOI: 10.1002/anie.202314398.
Peng Xiong's work on asymmetric photoelectrocatalysis published in Nature Catalysis: Nat. Catal. 2023, DOI: 10.1038/s41929-023-01050-y.
Our JACS 2021 paper (10.1021/jacs.1c06637) on photoderacemization of ketones is one of the most cited JACS publications from 2020-2021!
Account on chiral-at-Ru nitrene-mediated asymmetric C-H functionalizations: Acc. Chem. Res. 2023, 56, 1128-1141.
Review on the role of metal stereogenicity in asymmetric transition metal catalysis: Chem. Rev. 2023, 123, 4764-4794.
The most economic synthesis of amino acids: Just one step starting from carboxylic acids! Nat. Synth. 2023, 2, 645-652.
Nemrud Demirel's publication on chiral-at-iron catalyst design was selected for the coverpicture (Organometallics 2022, Vol. 41, Issue 24)!
Using transition metal nitrenes for enantioselective C-H-oxygenation: Angew. Chem. Int. Ed. 2022, 61, e202211971.
Synform Article by Prof. Matteo Zanda highlighting our invented amino acid synthesis by stereocontrolled 1,3-nitrogen migration.
Amino acid synthesis made easy by novel stereocontrolled 1,3-nitrogen migration: Nat. Chem. 2022, 14, 566-573. See also "Behind the Paper".
Catalytic asymmetric electrosynthesis: J. Am. Chem. Soc. 2022, 144, 6964.
Enantioselective ring-closing C(sp3)-H amination with sulfamoyl azides highlighted in Organic Chemistry Portal: Click here.
First catalytic photoderacemization of ketones: J. Am. Chem. Soc. 2021, 143, 13393.
Design of a new chiral iron catalyst: ACS Catal. 2021, 11, 7467.
Our work on asymmetric ring-closing aminooxygenation of alkenes (Org. Lett. 2020, 22, 6653) is highlighted by Douglass F. Taber: Org. Chem. Highlights 2021, July 26.
Highly efficient amination of unactivated C-H bonds with a simple iron catalyst: Angew. Chem. Int. Ed. 2021, 60, 6314-6319. This work has been highlighted in Synfacts: Synfacts 2021, 17, 0377.
Our nitrene-mediated C-H oxygenation highlighted in Synfacts: Synfacts 2020, 16, 1430.
A novel reaction: C-H oxygenation via nitrene chemistry! Angew. Chem. Int. Ed. 2020, 59, 21706-21710.
Enantioselective C(sp3)-H amination of urea derivatives:Chem 2020, 6, 2024. See also highlight by Bas de Bruin.
Atroposelective synthesis with chiral-at-Rh catalyst: Angew. Chem. Int. Ed. 2020, 59, 13552.
Teaching an old dog new tricks. Complementing Ru-Pybox with cyclometalated NHC ligand for enantioselective nitrene chemistry: Angew. Chem. Int. Ed. 2020, 59, 12392.
News & Highlights
October 2024: Great summary of the Chiral-at-Metal Catalysis of our group: Poster from Felix designed for the "Fachbereichstag" 2024. PDF file here.
May 2023: Our publication on Enantioselective and enantioconvergent Fe-catalyzed C(sp3)-H amination to access chiral 2-imidazolidinones (Chin. J. Chem. 2023, 41, 2065-2070) receives the NHU-CJC award!
October 2022: Summary of Chiral-at-Metal Catalysis by our group. Nemrud's and Dominik's prize-winning poster for "Fachbereichstag" 2022. PDF file.
September 2022: European Patent Application on the catalytic asymmetric synthesis of amino acids from carboxylic acids in a single step.
March 2022: European Patent Application on the catalytic asymmetric synthesis of amino acids by 1,3-nitrogen migration.
Oct. 2021: Eric Meggers joins Chinese Journal of Chemistry (CJC) as an Associate Editor.
ERC Advanced Grant on the development of earth-abundant chiral-at-metal catalysts starting in 2021!
How did we get from enzyme inhibitor design to asymmetric catalysis? Read this Essay: Angew. Chem. Int. Ed. 2017, 56, 5668.
Previous LOEWE Research Cluster "SynChemBio": Link to ProLOEWE
Nature Catalysis publication on asymmetric electrochemistry: Nat. Catal. 2019, 2, 34-40. See also "Behind the Paper".
Nature publication on asymmetric photocatalysis: Nature 2014, 515, 100-103. See also News & Views Feature by Skubi and Yoon.
Others
Introduction to chiral-at-metal catalyst design in the Meggers group: Click here for Youtube video.