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Katharina Höfer
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With the display of the video I consent to the data transfer to YouTube. Data Protection Declaration .
Our research aims at discovering and characterizing new epitranscriptomic mechanisms of gene regulation based on NAD-RNAs. Our inter-disciplinary group focuses on the interaction of proteins with NAD-RNA to identify novel and important connections between redox biology, gene expression and regulation. In the M4C initiative, we aim at understanding the role of NAD-RNA and their interaction with the proteome of the cell for the regulation of cellular and metabolic processes – and use RNA modifications to create novel genetic circuits for synthetic biology.
Research Focus:
Microbes as Responders; Microbes providing Solutions
Key Publication(s):
Wolfram-Schauerte M, Pozhydaieva N, Grawenhoff J, Welp LM, Silbern I, Wulf A, Billau FA, Glatter T, Urlaub H, Jäschke A, *Höfer K. A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature 2023, 620, 1054–1062
Wolfram-Schauerte M, *Höfer K. NAD-capped RNAs - a redox cofactor meets RNA. Trends in Biochemical Sciences 2023, Vol. 48, Iss. 2, 142-155
