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Translational Infection Research
Translation is the process of effectively transferring results from research into clinical practice. The aim is to develop new diagnostic, preventive and therapeutic procedures for the treatment of infectious diseases as quickly as possible.
At the Institute of Virology, various translational research projects are carried out in cooperation with partners from industry and science. The existing experience and expertise from research into highly pathogenic viruses is used for the testing and application of new vaccines and antiviral drugs (e.g. against Ebola virus and highly pathogenic coronaviruses). Model systems are also being established that only mirror certain aspects of viral replication cycles and enable work under lower safety levels.
Preclinical Projects and Infrastructure:
- Animal experimental studies in the BSL-4 high containment laboratory (BSL-3/-4 Animal Facility)
- Emergency vaccines – Alphavirus Replicons
- Investigation of new antiviral agents against highly pathogenic coronaviruses
- Development of virus surrogate systems for quantification of neutralising antibodies against highly pathogenic viruses
- Nucleosid Booster Project
Clinical Projects
- Clinical immunomonitoring
- Vaccine Development MVA-MERS-S
- Development of neutralizing antibodies against MVA-MERS-S