Projects

• RP1 - Liefke Exploiting the tumor-suppressive role of the transcriptional repressor SAMD1 in pancreatic ductal adenocarcinoma (PDAC)
• RP2 - Reinartz Impact of the secretome of inflammatory macrophage subsets on the mesothelial architecture promoting ovarian carcinoma metastasis
• RP3 - Worzfeld B-plexin-mediated regulation of anti-tumor CD8+ T cell activity in the tumor microenvironment of pancreatic ductal adenocarcinoma
• RP4 - Huber CD8+ T cell dysfunction mediated by ovarian carcinoma ascites: role of lipid metabolism
• RP5 - Pogge von Strandmann / Alashkar Alhamwe Deciphering the tumor-promoting activity of the NKG2D/NKG2D-ligand system in OC
• RP6 - Gómez-Serrano Extracellular vesicles from tumor-associated adipocytes: characterization of their functional role in the ovarian cancer microenvironment
• RP7 - Stiewe Deciphering the mutant p53-instructed secretome
• RP8 - Kracht The role of CDK-NF-κB crosstalk in protein synthesis and secretion
• RP9 - Taudte / Gremke Thymidine phosphorylase secretion: a druggable metabolic alteration in the microenvironment of PI3K-inhibitor-resistant breast cancer
• RP10 - Schmitz Synthetic lethal targeting of metabolic pathways in ovarian cancer
• RP11 - Frech / Burchert Overcoming immunosuppressive mechanisms in leukemia
• Johannes Mayer Dendritic cell reprogramming through the tumor secretome leads to dysfunctional anti-tumor T cell responses