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Publications 2024

Beutgen VM, Shinkevich V, Pörschke J, Meena C, Steitz AM, Pogge von Strandmann, Graumann J, Gómez-Serrano M. Secretome analysis using Affinity Proteomics and Immunoassays: a focus on Tumor Biology. Mol Cell Proteomics. 2024 Aug 13:100830. doi: 10.1016/j.mcpro.2024.100830
Simon C, Brunke ID, Stielow B, Forné I, Steitz AM, Geller M, Rohner I, Weber LM, Fischer S, Jeude LM, Huber M, Nist A, Stiewe T, Huber M, Buchholz M, Liefke R. SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma. PLos Biol. 2024 Aug 13;22(8):e3002739. doi: 101371/journal.pbio.3002739
Alashkar Alhamwe B, Ponath V, Alhamdan F, Dörsam B, Landwehr C, Linder M, Pauck Kim, Miethe S, Garn H, Finkernagel F, Brichkina A, Lauth M, Tiwari DK, Buchholz M, Bachurski D, Elmshäuser S, Nist A, Stiewe T, Pogge von Strandmann L, Szymański W, Beutgen V, Graumann J, Teply-Szymański J, Keber C, Denkert C, Jacob R, Preußer C, Pogge von Strandmann E. BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells. Cellular & Molecular Immunology; doi: 10.1038/s41423-024-01195-1 
Brichkina A, Ems MSuezov R, Singh R, Lutz V, Picard FSR, Nist A, Stiewe T, Graumann J, Daude M, Diederich WE, Finkernagel F, Chung HR, Bartsch DK, Roth K, Keber C, Denkert C, Huber M, Gress TM, Lauth M. DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer. GUT 2024 ;0:1-18. doi: 10.1136/gutjnl-2023-331854
Fischer S, Weber LM, Stielow B, Frech M, Simon C, Geller M, Könnecke J, Finkernagel F, Forné I, Nist A, Bauer UM, Stiewe T,  Neubauer A, Liefke R. IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells. Nucleic Acids Res . 2024 May 27:gkae437. doi: 10.1093/nar/gkae437
Alkhayer R, Ponath V, Pogge von Strandmann E. enChIP Protocol: Targeting a promoter region using the CRISPR/dCas9 system in human embryonic kidney cells (HEK293) for single-locus proteomics. STAR Protoc. 2024 Apr 30;5(2):103045. doi: 10.1016/j.xpro.2024.103045
Neuhaus F, Lieber S, Shinkevich VSteitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M (2024) Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells. Clin Transl Med. 2024 Apr;14(4):e1604. doi: 10.1002/ctm2.1604
Dreute J, Pfisterer M, Schmitz ML. A reductionist perspective on HIF-1α's role in cell proliferation under non-hypoxic conditions. Biochim Biophys Acta Mol Cell Res. 2024 Jan 30:119683. doi: 10.1016/j.bbamcr.2024.119683