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Publications of subproject TP6new

Desmosomal hyper-adhesion and heterophilic desmoglein interactions in pemphigus

Original papers

Fuchs M, Kugelmann D, Schlegel N, Vielmuth F*, Waschke J*. Desmoglein 2 can undergo Ca 2+-dependent interactions with both desmosomal and classical cadherins including E-cadherin and N-cadherin. Biophys J. 2022 Feb 17:S0006-3495(22)00147-3. *contributed equally. https://doi.org/10.1016/j.bpj.2022.02.023

Büchau F, Vielmuth F, Waschke J, Magin M. Bidirectional regulation of hyperadhesion by keratin filaments and desmosomal components Cell. Mol. Life Sciences. 2022 Apr 5;79(5):223. doi:10.1007/s00018-022-04244-y

Sigmund A., Steinert LS., Egu DT., Bayerbach FC., Waschke J., Vielmuth F. Dsg2 Upregulation as a Rescue Mechanism in Pemphigus. Front Immunol. 2020 Oct 28;11:581370. eCollection 2020. https://doi.org/10.3389/fimmu.2020.581370

Fuchs M., Sigmund A., Waschke J., Vielmuth F. Desmosomal hyper-adhesion of keratinocytes is accompanied with enhanced binding strength of desmoglein 3 molecules. Biophys J. 2020 Oct 20;119(8):1489-1500. Epub 2020 Sep 21. https://doi.org/10.1016/j.bpj.2020.09.008

Wanuske MT, Brantschen D, Schinner C, Stüdle C, Walter E, Hiermaier M, Vielmuth F, Waschke J, Spindler V. Clustering of desmosomal cadherins by desmoplakin is essential for cell-cell adhesion. Acta Physiol. 2022, 231(4): e13609. https://doi.org/10.1111/apha.13609