18.12.2024 Harnessing Click Chemistry and Light for Precise Analysis and Control of mRNA

Prof. Andrea Rentmeister from Ludwig-Maximilians Universität in Munich engaged in a lively discussion with a full house.

On 17 December, we welcomed Andrea Rentmeister to RTG 2937. The professor in Munich is also Chair of Organic and Biological Chemistry at her university. spoke about "Harnessing Click Chemistry and Light for Precise Analysis and Control of mRNA" in the SYNMIKRO lecture hall.

Research in Andrea Rentmeister's lab focuses on RNA at the interface of chemistry and biochemistry and aims to understand and ultimately control the processes affecting mRNA expression and turnover: "We aim to understand mechanisms and control processes governing mRNA expression and turnover. To address these fundamental problems, we take a chemical perspective and develop chemical and chemo-enzymatic tools for manipulation, analysis, and control of mRNA at the molecular level. Our broad methodological scope – comprising purely chemical as well as chemo-enzymatic approaches –allows us to choose the best strategy to achieve our goals, independent of the specific tool. Importantly, our work does not stop at chemical synthesis. We strive to implement chemical modifications in living human cells and push the limits further to applications in vivo. Our group has a track record of research in RNA chemical biology, cofactor and protein engineering." Click here to learn more about Andrea Rentmeister's research.

Thank you for the impulses you gave us! We hope you enjoyed your stay as much as we did.