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B05 - Social interaction predictors of symptom change in major depression

Nina Alexander, Philipp Kanske

Socio-affective processes, like empathic affect sharing, connect individual emotions to social interaction partners. Project B05 provides an in-depth understanding of social network predictors of disease trajectories in depression using multiple methods in both experimental and naturalistic settings. The study focuses on 200 dyads of depressed patients/healthy controls and their partners, examining the impact of negative affect transmission across multiple biological pathways on depressive symptom changes. Findings aim to reveal the role of maladaptive social interactions in depression, informing personalized interventions.